| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Holm BC et al. | The arthritogenic adjuvant squalene does not accumulate in joints, but gives rise to pathogenic cells in both draining and non-draining lymph nodes. | 2002 | Clin. Exp. Immunol. | pmid:11966758 |
| Andersson HC | Disorders of post-squalene cholesterol biosynthesis leading to human dysmorphogenesis. | 2002 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:11990452 |
| Lewis RW | The squalene content of atheromatous plaques. A re-examination. | 1975 Nov-Dec | Atherosclerosis | pmid:1201156 |
| Sanina OL and Datsenko ZM | [Sterol composition of sarcolemma in normal rabbits and in experimental muscular dystrophy]. | 1975 Nov-Dec | Ukr Biokhim Zh | pmid:1202710 |
| Uchino T et al. | Effect of squalene monohydroperoxide on cytotoxicity and cytokine release in a three-dimensional human skin model and human epidermal keratinocytes. | 2002 | Biol. Pharm. Bull. | pmid:12033500 |
| Nestel PJ and Kudchodkar B | Plasma squalene as an index of cholesterol synthesis. | 1975 | Clin Sci Mol Med | pmid:1204294 |
| Visioli F and Galli C | Biological properties of olive oil phytochemicals. | 2002 | Crit Rev Food Sci Nutr | pmid:12058980 |
| Spanggord RJ et al. | Development and application of an analytical method for the determination of squalene in formulations of anthrax vaccine adsorbed. | 2002 | J Pharm Biomed Anal | pmid:12062677 |
| Gauci C et al. | Molecular cloning of a vaccine antigen against infection with the larval stage of Echinococcus multilocularis. | 2002 | Infect. Immun. | pmid:12065546 |
| Passi S et al. | Lipophilic antioxidants in human sebum and aging. | 2002 | Free Radic. Res. | pmid:12069113 |
| Morimoto Y et al. | Asymmetric total synthesis of highly symmetric squalene-derived cytotoxic polyethers. | 2002 | Chirality | pmid:12112332 |
| Hoshino T and Ohashi S | Importance of the methyl group at C10 of squalene for hopene biosynthesis and novel carbocyclic skeletons with 6/5 + 5/5 + (6) ring system(s). | 2002 | Org. Lett. | pmid:12123374 |
| Asa PB et al. | Antibodies to squalene in recipients of anthrax vaccine. | 2002 | Exp. Mol. Pathol. | pmid:12127050 |
| Asano KG et al. | Chemical composition of fingerprints for gender determination. | 2002 | J. Forensic Sci. | pmid:12136987 |
| Pérez-Camino MC et al. | Determination of esters of fatty acids with low molecular weight alcohols in olive oils. | 2002 | J. Agric. Food Chem. | pmid:12137504 |
| Jarstfer MB et al. | Recombinant squalene synthase. Synthesis of non-head-to-tail isoprenoids in the absence of NADPH. | 2002 | J. Am. Chem. Soc. | pmid:12137536 |
| Blagg BS et al. | Recombinant squalene synthase. A mechanism for the rearrangement of presqualene diphosphate to squalene. | 2002 | J. Am. Chem. Soc. | pmid:12137537 |
| Matyas GR et al. | Induction and detection of antibodies to squalene. II. Optimization of the assay for murine antibodies. | 2002 | J. Immunol. Methods | pmid:12165433 |
| Connolly JD and Hill RA | Triterpenoids. | 2002 | Nat Prod Rep | pmid:12195814 |
| Hess BA | Concomitant C-ring Expansion and D-ring formation in lanosterol biosynthesis from squalene without violation of Markovnikov's rule. | 2002 | J. Am. Chem. Soc. | pmid:12197724 |