| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kribii R et al. | Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase--involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway. | 1997 | Eur. J. Biochem. | pmid:9363754 |
| Cataldo DM and Van Nest G | The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. | 1997 | Vaccine | pmid:9364672 |
| Tomasi M et al. | Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. | 1997 | Eur. J. Immunol. | pmid:9368632 |
| Salamon Z et al. | Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties. | 1997 | Biophys. J. | pmid:9370473 |
| Toews AD et al. | Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. | 1997 | Brain Res. Mol. Brain Res. | pmid:9387870 |
| Gloor M et al. | Biochemical and physiological parameters on the healthy skin surface of patients with common warts. | 1976 | Dermatologica | pmid:939341 |
| Law S et al. | Skin surface lipids inhibit adherence of Candida albicans to stratum corneum. | 1997 | Dermatology (Basel) | pmid:9407165 |
| Newmark HL | Squalene, olive oil, and cancer risk: a review and hypothesis. | 1997 | Cancer Epidemiol. Biomarkers Prev. | pmid:9419410 |
| Ceruti M et al. | 29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. | 1998 | J. Med. Chem. | pmid:9484504 |
| Rao CV et al. | Chemopreventive effect of squalene on colon cancer. | 1998 | Carcinogenesis | pmid:9498278 |
| O'Hagan DT | Recent advances in vaccine adjuvants for systemic and mucosal administration. | 1998 | J. Pharm. Pharmacol. | pmid:9504429 |
| Lopez D et al. | Compensatory responses to inhibition of hepatic squalene synthase. | 1998 | Arch. Biochem. Biophys. | pmid:9514656 |
| Basáñez G et al. | Effect of single chain lipids on phospholipase C-promoted vesicle fusion. A test for the stalk hypothesis of membrane fusion. | 1998 | Biochemistry | pmid:9521711 |
| Stoskopf MK et al. | The impact of water temperature on core body temperature of North American river otters (Lutra canadensis) during simulated oil spill recovery washing protocols. | 1997 | J. Zoo Wildl. Med. | pmid:9523634 |
| Sato T et al. | Overexpression of squalene-hopene cyclase by the pET vector in Escherichia coli and first identification of tryptophan and aspartic acid residues inside the QW motif as active sites. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9532806 |
| Zheng YF et al. | Inhibition kinetics and affinity labeling of bacterial squalene:hopene cyclase by thia-substituted analogues of 2, 3-oxidosqualene. | 1998 | Biochemistry | pmid:9558334 |
| Saat YA and Bloch KE | Effect of a supernatant protein on microsomal squalene epoxidase and 2,3-oxidosqualene-lanosterol cyclase. | 1976 | J. Biol. Chem. | pmid:956181 |
| Smith TJ et al. | Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis by dietary olive oil and squalene. | 1998 | Carcinogenesis | pmid:9600360 |
| Sajbidor J et al. | Influence of new fenpropimorph fungicides on the growth and sterol composition in Saccharomyces cerevisiae: relationship between structure and activity. | 1998 | J. Pharm. Pharmacol. | pmid:9600722 |
| Patt TE and Hanson RS | Intracytoplasmic membrane, phospholipid, and sterol content of Methylobacterium organophilum cells grown under different conditions. | 1978 | J. Bacteriol. | pmid:96093 |