| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nguyen HT et al. | Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. | 2013 | Plant Physiol. Biochem. | pmid:24036394 |
| Borchman D et al. | Confirmation of the presence of squalene in human eyelid lipid by heteronuclear single quantum correlation spectroscopy. | 2013 | Lipids | pmid:24081494 |
| Rajaram K et al. | Comparative bioactive studies between wild plant and callus culture of Tephrosia tinctoria pers. | 2013 | Appl. Biochem. Biotechnol. | pmid:24026411 |
| Villa M et al. | Safety of MF59-adjuvanted influenza vaccination in the elderly: results of a comparative study of MF59-adjuvanted vaccine versus nonadjuvanted influenza vaccine in northern Italy. | 2013 | Am. J. Epidemiol. | pmid:23863759 |
| Vono M et al. | The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24324152 |
| Pannkuk EL et al. | Sebaceous lipid profiling of bat integumentary tissues: quantitative analysis of free Fatty acids, monoacylglycerides, squalene, and sterols. | 2013 | Chem. Biodivers. | pmid:24327437 |
| Tegenge MA and Mitkus RJ | A physiologically-based pharmacokinetic (PBPK) model of squalene-containing adjuvant in human vaccines. | 2013 | J Pharmacokinet Pharmacodyn | pmid:23912214 |
| Hosogaya N et al. | The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 in Candida glabrata. | 2013 | FEMS Yeast Res. | pmid:23496820 |
| Rappuoli R | Vaccine adjuvants: the future is bright. Interview by Jenaid Rees. | 2013 | Expert Rev Vaccines | pmid:23829664 |
| Trung Bui D et al. | Polymer prodrug nanoparticles based on naturally occurring isoprenoid for anticancer therapy. | 2013 | Biomacromolecules | pmid:23829862 |
| Bruun Laursen A | [Catastrophic consequences of Pandemrix swine flu vaccine containing squalene]. | 2013 | Ugeskr. Laeg. | pmid:23833781 |
| Mølbak K | [Squalene unlikely sinner]. | 2013 | Ugeskr. Laeg. | pmid:23833782 |
| Gefenaite G et al. | Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination. | 2013 | PLoS ONE | pmid:23840413 |
| Fox CB and Haensler J | An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants. | 2013 | Expert Rev Vaccines | pmid:23885820 |
| Sisco E et al. | Evaluation of C60 secondary ion mass spectrometry for the chemical analysis and imaging of fingerprints. | 2013 | Forensic Sci. Int. | pmid:23890648 |
| King KL et al. | Inelastic scattering of OH radicals from organic liquids: isolating the thermal desorption channel. | 2013 | Phys Chem Chem Phys | pmid:23807737 |
| Son J et al. | Immunogenicity of low-dose MF59-adjuvanted 2009 influenza A/H1N1 vaccine in dialysis patients. | 2013 | Clin. Exp. Nephrol. | pmid:22990301 |
| Durier C et al. | Long-term immunogenicity of two doses of 2009 A/H1N1v vaccine with and without AS03(A) adjuvant in HIV-1-infected adults. | 2013 | AIDS | pmid:23018437 |
| Lin YK et al. | Squalene-containing nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of diphencyprone for treating alopecia areata. | 2013 | Pharm. Res. | pmid:23070602 |
| Ueda D et al. | Cyclization of squalene from both termini: identification of an onoceroid synthase and enzymatic synthesis of ambrein. | 2013 | J. Am. Chem. Soc. | pmid:24274794 |