| MeSH term | MeSH ID | Detail |
|---|---|---|
| Photosensitivity Disorders | D010787 | 8 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Scalp Dermatoses | D012536 | 11 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
| Viremia | D014766 | 4 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Simian Acquired Immunodeficiency Syndrome | D016097 | 4 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Persian Gulf Syndrome | D018923 | 1 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Arias JL et al. | Magnetoresponsive squalenoyl gemcitabine composite nanoparticles for cancer active targeting. | 2008 | Langmuir | pmid:18540685 |
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| Tong R and McDonald FE | Mimicking biosynthesis: total synthesis of the triterpene natural product abudinol B from a squalene-like precursor. | 2008 | Angew. Chem. Int. Ed. Engl. | pmid:18459096 |
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| Schultze V et al. | Safety of MF59 adjuvant. | 2008 | Vaccine | pmid:18462843 |
| Zhang JX et al. | Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. | 2008 | Chem. Senses | pmid:18515819 |
| Metzger P et al. | Braunicetals: acetals from condensation of macrocyclic aldehydes and terpene diols in Botryococcus braunii. | 2008 | Phytochemistry | pmid:18639308 |
| Catalán J et al. | The photophysics of all-trans polyenes from ttbP5, a nonphotolabile pentaene. | 2008 | J Chem Phys | pmid:18624481 |
| Mosca F et al. | Molecular and cellular signatures of human vaccine adjuvants. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18650390 |
| Huber VC and McCullers JA | Vaccines against pandemic influenza: what can be done before the next pandemic? | 2008 | Pediatr. Infect. Dis. J. | pmid:18820570 |
| Nováková Z et al. | Membrane proteins and squalene-hydrosqualene profile in methanoarchaeon Methanothermobacter thermautotrophicus resistant to N,N'-dicyclohexylcarbodiimide. | 2008 | Folia Microbiol. (Praha) | pmid:18661300 |
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| Radosević K et al. | Antibody and T-cell responses to a virosomal adjuvanted H9N2 avian influenza vaccine: impact of distinct additional adjuvants. | 2008 | Vaccine | pmid:18514980 |
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| Miettinen TA et al. | Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study. | 2008 | Atherosclerosis | pmid:18178213 |
| Wack A et al. | Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice. | 2008 | Vaccine | pmid:18162266 |
| Zhang W et al. | Feeding with supplemental squalene enhances the productive performance in boars. | 2008 | Anim. Reprod. Sci. | pmid:18164149 |
| Couvreur P et al. | Discovery of new hexagonal supramolecular nanostructures formed by squalenoylation of an anticancer nucleoside analogue. | 2008 | Small | pmid:18247384 |
| Babiychuk E et al. | Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18287026 |
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| Chang MH et al. | The isolation and characterization of Pseudozyma sp. JCC 207, a novel producer of squalene. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18299826 |
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| Lee S and Poulter CD | Cloning, solubilization, and characterization of squalene synthase from Thermosynechococcus elongatus BP-1. | 2008 | J. Bacteriol. | pmid:18375558 |
| Seubert A et al. | The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells. | 2008 | J. Immunol. | pmid:18390722 |
| Yoon J et al. | Rubritalea sabuli sp. nov., a carotenoid- and squalene-producing member of the family Verrucomicrobiaceae, isolated from marine sediment. | 2008 | Int. J. Syst. Evol. Microbiol. | pmid:18398208 |
| Helske S et al. | Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves. | 2008 | J. Lipid Res. | pmid:18398220 |
| Tan MA et al. | Antitubercular triterpenes and phytosterols from Pandanus tectorius Soland. var. laevis. | 2008 | J Nat Med | pmid:18404330 |
| Kwon SM et al. | In vivo time-dependent gene expression of cationic lipid-based emulsion as a stable and biocompatible non-viral gene carrier. | 2008 | J Control Release | pmid:18384902 |
| Kanaji N et al. | Positron emission tomography-positive squalene-induced lipoid pneumonia confirmed by gas chromatography-mass spectrometry of bronchoalveolar lavage fluid. | 2008 | Am. J. Med. Sci. | pmid:18414072 |