(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Brain Diseases D001927 27 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Acne Vulgaris D000152 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Van Leusden H and Villee CA The de novo synthesis of sterols and steroids from acetate by preparations of human term placenta. 1965 Steroids pmid:5857495
Kipping D [Observations on skin surface fats]. 1965 Z Haut Geschlechtskr pmid:5860995
KARLSON P [NOBEL PRIZE FOR MEDICINE AND PHYSIOLOGY IN 1964]. 1965 Dtsch. Med. Wochenschr. pmid:14238764
CORNFORTH JW et al. THE MIGRATION AND ELIMINATION OF HYDROGEN DURING BIOSYNTHESIS OF CHOLESTEROL FROM SQUALENE. 1965 J. Am. Chem. Soc. pmid:14329430
DIPLOCK AT et al. VITAMIN A AND ISOPRENOID SYNTHESIS IN THE RAT. 1965 Biochem. J. pmid:14333548
Stone KJ and Hemming FW The incorporation of [2-14C, 4R-3H1] mevalonate and [2-14C, 4S-3H1] mevalonate into squalene, ubiquinone and ergosterol of Aspergillus fumigatus Fresenius. 1965 Biochem. J. pmid:4284430
Dalidowicz JE and McDonald HJ Site of the in vitro inhibition of cholesterol biosynthesis by tolbutamide and phenethylbiguanide. 1965 Biochemistry pmid:4284598
Gosselin L and Duvivier J [On the utilization of C14-2-mevalonic acid by cell fractions of bovine adrenal gland homogenates]. 1965 Arch. Int. Physiol. Biochim. pmid:4158100
Garbuzov AG et al. [The presence of squalene in the human aorta]. 1965 Arkh. Patol. pmid:5881137
Goodwin TW and Williams RJ A mechanism for the biosynthesis of alpha-carotene. 1965 Biochem. J. pmid:5881648