Palamarchuk VI et al. |
[Radiation-induced changes in the content of squalene, lathosterol and cholesterol in rat blood proteins]. |
1991 May-Jun |
Radiobiologiia |
pmid:1887013
|
Vuoristo M et al. |
Cholesterol malabsorption in pancreatic insufficiency: effects of enzyme substitution. |
1992 |
Gastroenterology |
pmid:1732134
|
Yeo HC and Shibamoto T |
Formation of formaldehyde and malonaldehyde by photooxidation of squalene. |
1992 |
Lipids |
pmid:1608304
|
Melnykovych G et al. |
Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1632790
|
Nikkilä K et al. |
Serum and hepatic cholestanol, squalene and noncholesterol sterols in man: a study on liver transplantation. |
1992 |
Hepatology |
pmid:1568728
|
Kamimura H et al. |
Enhanced elimination of theophylline, phenobarbital and strychnine from the bodies of rats and mice by squalane treatment. |
1992 |
J. Pharmacobio-dyn. |
pmid:1527697
|
Schulz S et al. |
Mechanisms of cell growth inhibition and cell cycle arrest in human colonic adenocarcinoma cells by dehydroepiandrosterone: role of isoprenoid biosynthesis. |
1992 |
Cancer Res. |
pmid:1531325
|
Allison AC and Byars NE |
Syntex adjuvant formulation. |
1992 |
Res. Immunol. |
pmid:1439132
|
Bai M et al. |
Epoxidation of 2,3-oxidosqualene to 2,3;22,23-squalene dioxide by squalene epoxidase. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1599468
|
Van Sickle WA et al. |
Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture. |
1992 |
Lipids |
pmid:1326069
|
Murakoshi M et al. |
Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis. |
1992 |
Int. J. Cancer |
pmid:1334056
|
Sherman DR et al. |
Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris. |
1992 |
Science |
pmid:1470914
|
Tait RM |
Development of a radiometric spot-wash assay for squalene synthase. |
1992 |
Anal. Biochem. |
pmid:1416027
|
Nikkilä K et al. |
Liver transplantation modifies serum cholestanol, cholesterol precursor and plant sterol levels. |
1992 |
Clin. Chim. Acta |
pmid:1499139
|
Cenedella RJ et al. |
Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1510688
|
Taton M et al. |
Inhibition of 2,3-oxidosqualene cyclases. |
1992 |
Biochemistry |
pmid:1510977
|
Boutaud O et al. |
Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1445330
|
Abe I et al. |
Affinity labeling of vertebrate oxidosqualene cyclases with a tritiated suicide substrate. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1520315
|
Ceruti M et al. |
2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase. |
1992 |
J. Med. Chem. |
pmid:1501233
|
Silva CJ and Djerassi C |
Biosynthetic studies of marine lipids 36. The origin of common sterol side chains in eleven sponges using [3-3H]-squalene. |
1992 Jan-Feb |
Comp. Biochem. Physiol., B |
pmid:1499273
|
Fujita H and Matsuo I |
Type I lipid photo-oxidation by the nonsteroidal anti-inflammatory drug suprofen: a possible key to its photosensitivity. |
1992-1993 Oct |
Photodermatol Photoimmunol Photomed |
pmid:1342189
|
Ciosek CP et al. |
Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo. |
1993 |
J. Biol. Chem. |
pmid:8227045
|
Vanhanen HT et al. |
Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment. |
1993 |
J. Lipid Res. |
pmid:8228636
|
Balliano G et al. |
3-Carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase. |
1993 |
Lipids |
pmid:8246689
|
Corsini A et al. |
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. |
1993 |
Atherosclerosis |
pmid:8216498
|
Mercer EI |
Inhibitors of sterol biosynthesis and their applications. |
1993 |
Prog. Lipid Res. |
pmid:8309949
|
Lohner K et al. |
Squalene promotes the formation of non-bilayer structures in phospholipid model membranes. |
1993 |
Biochim. Biophys. Acta |
pmid:8399307
|
Kawakami T et al. |
Squalane as a possible carrier of bone morphogenetic protein. |
1993 |
Biomaterials |
pmid:8399948
|
Storm HM et al. |
Radioprotection of mice by dietary squalene. |
1993 |
Lipids |
pmid:8355581
|
Balliano G et al. |
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. |
1993 |
FEBS Lett. |
pmid:8462686
|
Crispino GA et al. |
Selective perhydroxylation of squalene: taming the arithmetic demon. |
1993 |
Science |
pmid:8418495
|
Asnis DS et al. |
Shark oil pneumonia. An overlooked entity. |
1993 |
Chest |
pmid:8449116
|
Henk G and Heinz T |
[Hydrocarbon content in the fat of meat pigs after feeding "Fermosin"]. |
1993 |
Arch Tierernahr |
pmid:8572916
|
Prashad M |
Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate. |
1993 |
J. Med. Chem. |
pmid:8496942
|
Horie M et al. |
An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells. |
1993 |
Biochim. Biophys. Acta |
pmid:8504141
|
Seo S et al. |
Effect of sterol biosynthesis inhibitor, SSF-109, on cholesterol synthesis in isolated rat hepatocytes. |
1993 |
Steroids |
pmid:8484187
|
Someya K et al. |
The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. |
1994 |
J. Nutr. Sci. Vitaminol. |
pmid:7844638
|
Balliano G et al. |
Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. |
1994 |
Antimicrob. Agents Chemother. |
pmid:7810997
|
Kamimura N et al. |
Construction of squalene-accumulating Saccharomyces cerevisiae mutants by gene disruption through homologous recombination. |
1994 |
Appl. Microbiol. Biotechnol. |
pmid:7765777
|
Rabiskova M et al. |
The influence of surface properties on uptake of oil into complex coacervate microcapsules. |
1994 |
J. Pharm. Pharmacol. |
pmid:7815274
|
Fujita H and Matsuo I |
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. |
1994 |
Photodermatol Photoimmunol Photomed |
pmid:7880759
|
Hilgers LA et al. |
A novel non-mineral oil-based adjuvant. I. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in laboratory animals. |
1994 |
Vaccine |
pmid:8085385
|
Hilgers LA et al. |
A novel non-mineral oil-based adjuvant. II. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in pigs. |
1994 |
Vaccine |
pmid:8085386
|
Wieland B et al. |
Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus. |
1994 |
J. Bacteriol. |
pmid:8002598
|
Byars NE et al. |
Vaccinating guinea pigs with recombinant glycoprotein D of herpes simplex virus in an efficacious adjuvant formulation elicits protection against vaginal infection. |
1994 |
Vaccine |
pmid:8165851
|
Dollis D and Schuber F |
Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2. |
1994 |
Biochem. Pharmacol. |
pmid:8043030
|
Gylling H and Miettinen TA |
Postabsorptive metabolism of dietary squalene. |
1994 |
Atherosclerosis |
pmid:8060377
|
Abe I |
[Bioorganic chemistry of squalene cyclase]. |
1994 |
Tanpakushitsu Kakusan Koso |
pmid:8090933
|
Pogliani L et al. |
An NMR and molecular mechanics study of squalene and squalene derivatives. |
1994 |
Chem. Phys. Lipids |
pmid:8013054
|
Giron MD et al. |
Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells. |
1994 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8022795
|
Domnas A et al. |
Squalene metabolism in two species of Lagenidium. |
1994 |
Can. J. Microbiol. |
pmid:8076247
|
Sunthornandh P and Ratanabanangkoon K |
A comparative study of three vehicles on antibody responses against elapid snake neurotoxin immunogens. |
1994 |
Toxicon |
pmid:8079368
|
Ren Z and Gould MN |
Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. |
1994 |
Cancer Lett. |
pmid:8149348
|
Mookhtiar KA et al. |
Yeast squalene synthase. A mechanism for addition of substrates and activation by NADPH. |
1994 |
J. Biol. Chem. |
pmid:8157649
|
Florin-Christensen M et al. |
Occurrence of specific sterols in Pneumocystis carinii. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8292026
|
Miettinen TA and Vanhanen H |
Serum concentration and metabolism of cholesterol during rapeseed oil and squalene feeding. |
1994 |
Am. J. Clin. Nutr. |
pmid:8310985
|
Inoue H et al. |
Phosphorylation of farnesol by a cell-free system from Botryococcus braunii. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8179579
|
Ohkawa S et al. |
Immune responses induced by prototype vaccines for AIDS in rhesus monkeys. |
1994 |
AIDS Res. Hum. Retroviruses |
pmid:8179961
|
Valensi JP et al. |
Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants. |
1994 |
J. Immunol. |
pmid:7930610
|
Kahn JO et al. |
Clinical and immunologic responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers. |
1994 |
J. Infect. Dis. |
pmid:7963729
|
Hoffman SL et al. |
Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant. |
1994 |
Am. J. Trop. Med. Hyg. |
pmid:7985753
|
Abe I et al. |
Inhibitors of squalene biosynthesis and metabolism. |
1994 |
Nat Prod Rep |
pmid:15200015
|
Yoshino S and Yoshino J |
Recruitment of pathogenic T cells to synovial tissues of rats injected intraarticularly with nonspecific agents. |
1994 |
Cell. Immunol. |
pmid:7522973
|
Gylling H et al. |
Postprandial vitamin A and squalene clearances and cholesterol synthesis off and on lovastatin treatment in type III hyperlipoproteinemia. |
1995 |
Atherosclerosis |
pmid:7669084
|
Lees ND et al. |
Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. |
1995 |
Lipids |
pmid:7791529
|
Abe I and Prestwich GD |
Identification of the active site of vertebrate oxidosqualene cyclase. |
1995 |
Lipids |
pmid:7791531
|
Cattel L et al. |
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. |
1995 |
Lipids |
pmid:7791532
|
Houston L et al. |
Response of guinea pigs to a vaccine containing a new adjuvant (SAF) and gram-negative bacteria. |
1995 |
Lab. Anim. Sci. |
pmid:7752616
|
Langenberg AG et al. |
A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]. |
1995 |
Ann. Intern. Med. |
pmid:7755223
|
Yamamoto A et al. |
Impaired water barrier function in acne vulgaris. |
1995 |
Arch. Dermatol. Res. |
pmid:7763094
|
Vanhanen HT and Miettinen TA |
Cholesterol absorption and synthesis during pravastatin, gemfibrozil and their combination. |
1995 |
Atherosclerosis |
pmid:7661873
|
Fliesler SJ et al. |
Isoprenoid lipid metabolism in the retina: dynamics of squalene and cholesterol incorporation and turnover in frog rod outer segment membranes. |
1995 |
Exp. Eye Res. |
pmid:7720806
|
Kerwin JL et al. |
Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum. |
1995 |
Microbiology (Reading, Engl.) |
pmid:7704271
|
Ott G et al. |
Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59. |
1995 |
Vaccine |
pmid:8578842
|
Piretti MV et al. |
Simultaneous reversed-phase high-performance liquid chromatographic separation of non-polar isoprenoid lipids and their determination. |
1995 |
J. Chromatogr. B, Biomed. Appl. |
pmid:8788146
|
Socaciu C et al. |
In vitro yeast (Saccharomyces cerevisiae) presqualene and squalene synthesis related to substrate and cofactor availability. |
1995 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:8521075
|
Boutaud O et al. |
Retention of the label during the conversion of [3-3H] squalene into (3S)-2,3-oxidosqualene catalyzed by mammalian squalene oxidase. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7887959
|
Robuccio JA et al. |
Comparison of the effects of five adjuvants on the antibody response to influenza virus antigen in guinea pigs. |
1995 |
Lab. Anim. Sci. |
pmid:7474883
|
Lewis D et al. |
Enzyme inhibition during the conversion of squalene to cholesterol. |
1995 |
Steroids |
pmid:7482633
|
Pittler SJ et al. |
In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure. |
1995 |
J. Cell Biol. |
pmid:7615641
|
Viola F et al. |
Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. |
1995 |
Biochem. Pharmacol. |
pmid:7575639
|
Ott G et al. |
MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. |
1995 |
Pharm Biotechnol |
pmid:7551221
|
Nagumo A et al. |
Purification and characterization of recombinant squalene epoxidase. |
1995 |
J. Lipid Res. |
pmid:7595073
|
Airaudi D et al. |
Preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes. |
1995 Jul-Aug |
Mycoses |
pmid:8559196
|
Bonté F et al. |
Simarouba amara extract increases human skin keratinocyte differentiation. |
1996 |
J Ethnopharmacol |
pmid:8844461
|
Traquina P et al. |
MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates. |
1996 |
J. Infect. Dis. |
pmid:8940205
|
Rangel H et al. |
Naturally azole-resistant Leishmania braziliensis promastigotes are rendered susceptible in the presence of terbinafine: comparative study with azole-susceptible Leishmania mexicana promastigotes. |
1996 |
Antimicrob. Agents Chemother. |
pmid:9124841
|
Gylling H et al. |
Delayed postprandial retinyl palmitate and squalene removal in a patient heterozygous for apolipoprotein A-IFIN mutation (Leu 159-->Arg) and low HDL cholesterol level without coronary artery disease. |
1996 |
Atherosclerosis |
pmid:9125314
|
Fujie T et al. |
Culture of cells derived from the human sebaceous gland under serum-free conditions without a biological feeder layer or specific matrices. |
1996 |
Arch. Dermatol. Res. |
pmid:8931874
|
Grimes DS et al. |
Sunlight, cholesterol and coronary heart disease. |
1996 |
QJM |
pmid:8935479
|
Krisans SK |
Cell compartmentalization of cholesterol biosynthesis. |
1996 |
Ann. N. Y. Acad. Sci. |
pmid:8993542
|
Nikkilä K et al. |
Serum squalene and noncholesterol sterols before and after delivery in normal and cholestatic pregnancy. |
1996 |
J. Lipid Res. |
pmid:9017519
|
Keefer MC et al. |
Safety and immunogenicity of Env 2-3, a human immunodeficiency virus type 1 candidate vaccine, in combination with a novel adjuvant, MTP-PE/MF59. NIAID AIDS Vaccine Evaluation Group. |
1996 |
AIDS Res. Hum. Retroviruses |
pmid:8744579
|
Dracheva S et al. |
Chemical and functional studies on the importance of purple membrane lipids in bacteriorhodopsin photocycle behavior. |
1996 |
FEBS Lett. |
pmid:8612754
|
Ito T et al. |
Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterol. |
1996 |
Gastroenterology |
pmid:8613070
|
Chan C et al. |
The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors. |
1996 |
J. Med. Chem. |
pmid:8568810
|
Miquel K et al. |
Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8780704
|
Higgins DA et al. |
MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice. |
1996 |
Vaccine |
pmid:8782343
|
Mark M et al. |
Effects of a novel 2,3-oxidosqualene cyclase inhibitor on the regulation of cholesterol biosynthesis in HepG2 cells. |
1996 |
J. Lipid Res. |
pmid:8820110
|
Arthington-Skaggs BA et al. |
Positive and negative regulation of a sterol biosynthetic gene (ERG3) in the post-squalene portion of the yeast ergosterol pathway. |
1996 |
FEBS Lett. |
pmid:8772195
|