(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

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Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Niemann-Pick Diseases D009542 25 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Cholestasis D002779 23 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Periodontitis D010518 22 associated lipids
Olfaction Disorders D000857 17 associated lipids
Xanthomatosis D014973 17 associated lipids
Cholelithiasis D002769 16 associated lipids
Celiac Disease D002446 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Pascaud A et al. [Turnover of the endogenous free cholesterol of the hepatic cell plasma membrane sinusoids]. 1979 Biochimie pmid:534664
Kushwaha SC and Kates M Effect of glycerol on carotenogenesis in the extreme halophile, Halobacterium cutirubrum. 1979 Can. J. Microbiol. pmid:540254
Kushwaha SC and Kates M Studies of the biosynthesis of C50 carotenoids in Halobacterium cutirubrum. 1979 Can. J. Microbiol. pmid:540255
Popják G and Agnew WS Squalene synthetase. 1979 Mol. Cell. Biochem. pmid:41173
Hirayama C et al. Serum cholesterol and squalene in hepatocellular carcinoma. 1979 Clin. Chim. Acta pmid:216506
Frier BM and Saudek CD Cholesterol metabolism in diabetes: the effect of insulin on the kinetics of plasma squalene. 1979 J. Clin. Endocrinol. Metab. pmid:511973
Adrangui M et al. [Water-surfactant-oil diagrams based on perhydrosqualene and triglycerides (Miglyol 812). Study of emulsion phases and stability]. 1979 Pharm Acta Helv pmid:515109
PokrovskiÄ­ AA et al. [Method of isolating, identifying and quantitatively determining alkanes, cycloalkanes, monocyclic arenes and squalene in animal organs and tissues]. 1978 Sep-Oct Vopr Pitan pmid:716335
PerederiÄ­ OF and Morozova RP [Squalene and sterols of rat stomach tissue and the effect of acetylsalicylic acid on their content]. 1978 Nov-Dec Ukr. Biokhim. Zh. pmid:749299
Anisimov MM et al. [Effect of triterpene glycosides on the biosynthesis of sterols and fatty acids by the yeast Saccharomyces carlsbergensis]. 1978 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:724665
Wood SG and Gottlieb D Evidence from mycelial studies for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. 1978 Biochem. J. pmid:637849
Wood SG and Gottlieb D Evidence from cell-free systems for differences in the sterol biosynthetic pathway of Rhizoctonia solani and Phytophthora cinnamomi. 1978 Biochem. J. pmid:637850
Wielgosz GJ and Armstrong DT Effects of prolactin, progesterone, and 17beta-hydroxy-5alpha-androstan-3-one on squalene production by the preputial gland of the immature female rat. 1978 Can. J. Physiol. Pharmacol. pmid:638868
Takeuchi N et al. Impairment of hepatic cholesterol synthesis from squalene and the function of hepatic sterol carrier protein system by ageing. 1978 Exp. Gerontol. pmid:639893
Amdur BH et al. Presence of squalene in gram-positive bacteria. 1978 J. Bacteriol. pmid:670148
Gavey KL and Scallen TJ Studies on the conversion of enzymatically generated, microsome-bound squalene to sterol. 1978 J. Biol. Chem. pmid:670211
Yamanishi Y et al. Serum squalene levels in hepatobiliary diseases. 1978 Clin. Chim. Acta pmid:679482
Kudchodkar BJ et al. Mechanisms of hypolipidemic action of nicotinic acid. 1978 Clin. Pharmacol. Ther. pmid:688728
Douglas TJ et al. Inhibition of cholesterol biosynthesis in ovine ovarian follicles in vitro by human chorionic gonadotrophin. 1978 Aust. J. Biol. Sci. pmid:571711
Tornabene TG Non-aerated cultivation of Halobacterium cutirubrum and its effect on cellular squalenes. 1978 J. Mol. Evol. pmid:691076
Tornabene TG et al. Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. 1978 J. Mol. Evol. pmid:691077
White SH Formation of "solvent-free" black lipid bilayer membranes from glyceryl monooleate dispersed in squalene. 1978 Biophys. J. pmid:698340
Tilvis RS et al. Release of newly synthesized squalene, methyl sterols and cholesterol from human adipocytes in the presence of lipoproteins. 1978 Scand. J. Clin. Lab. Invest. pmid:628820
Tiffany JM Individual variations in human meibomian lipid composition. 1978 Exp. Eye Res. pmid:710541
Saudek CD et al. Plasma squalene: lipoprotein distribution and kinetic analysis. 1978 J. Lipid Res. pmid:712242
Mironova VN and Chaialo PP [Cholesterol biosynthesis in the blood of rabbits with experimental atherosclerosis]. 1978 Biull Eksp Biol Med pmid:728610
Nishino T et al. Synthesis of dehydrosqualene in microsomal fraction of Saccharomyces cerevisiae. 1978 Biochem. Biophys. Res. Commun. pmid:32886
Yamawaki M et al. Antitumor activity of squalene-treated cell-wall skeleton of Nocardia rubra in mice. 1978 Gan pmid:103768
Patt TE and Hanson RS Intracytoplasmic membrane, phospholipid, and sterol content of Methylobacterium organophilum cells grown under different conditions. 1978 J. Bacteriol. pmid:96093
Goldberg I and Shechter I Occurrence of squalene in methanol-grown bacteria. 1978 J. Bacteriol. pmid:98521
Weeks OB and Francesconi MD Occurrence of squalene and sterols in Cellulomonas dehydrogenans (Arnaudi 1942) comb. nov. Hester 1971. 1978 J. Bacteriol. pmid:101527
Bertolino A et al. Polyisoprenoid amphiphilic compounds as inhibitors of squalene synthesis and other microsomal enzymes. 1978 Biochim. Biophys. Acta pmid:210830
Mills OH et al. Enhancement of comedogenic substances by ultraviolet radiation. 1978 Br. J. Dermatol. pmid:147099
Strauss JS et al. Surface lipid composition in children with protein-calorie malnutrition. 1978 Am. J. Clin. Nutr. pmid:414616
Cicchini T et al. [The importance of man, mouse and rat skin surface lipid fractions on the "in vitro" penetration of "Schistosoma mansoni" cercariae (author's transl)]. 1977 Sep-Oct Ann Sclavo pmid:616258
Boar RB and Damps K Resolution of 2,3-dihydrosqualene-2,3-diol, 10,11-dihydro-10,11-dihydroxyfarnesyl benzoate, and 6,7-dihydro-6,7-dihydroxygeranyl benzoate. Synthesis of (3R)- and (3S)-2,3-epoxy-2,3-dihydrosqualene. 1977 J. Chem. Soc. Perkin Trans. I pmid:558213
Wiss O and Wiss V On the influence of cholesterol feeding and of a lipogenic diet on the cholesterogenesis in rat liver in vivo. 1977 Helv. Chim. Acta pmid:599043
Puhvel SM and Sakamoto M An in vivo evaluation of the inflammatory effect of purified comedonal components in human skin. 1977 J. Invest. Dermatol. pmid:143497
Gloor M and Karenfeld A Effect of ultraviolet light therapy, given over a period of several weeks, on the amount and composition of the skin surface lipids. 1977 Dermatologica pmid:844642
Kohasi O et al. Arthritogenicity of wax D from various mycobacteria related to oil vehicle composition and to the combination with poly I:C, cord factor and acetylated wax D. 1977 Int. Arch. Allergy Appl. Immunol. pmid:852904
McKean ML and Nes WR Delayed conversion of squalene to sterols during development of Pinus pinea seeds. 1977 Lipids pmid:853880
Ferguson JB and Bloch K Purification and properties of a soluble protein activator of rat liver squalene epoxidase. 1977 J. Biol. Chem. pmid:885856
Dogliotti M et al. Nutritional influences of pellagra on sebum composition. 1977 Br. J. Dermatol. pmid:889695
Kohashi O et al. Effect of oil composition on both adjuvant-induced arthritis and delayed hypersensitivity to purified protein derivative and peptidoglycans in various rat strains. 1977 Infect. Immun. pmid:892904
Downing DT et al. The time course of lipid formation in human sebaceous glands. 1977 J. Invest. Dermatol. pmid:903669
Wiss O and Wiss V On metabolic degradations of squalene, lanosterol and cholesterol in rat liver in vivo. Evidence for recycling of metabolites for the synthesis of isoprene compounds. 1977 Helv. Chim. Acta pmid:914630
Cornforth J Symmetry of squalene epoxidation in vivo. 1977 Proc. R. Soc. Lond., B, Biol. Sci. pmid:22855
Karst F and Lacroute F Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway. 1977 Mol. Gen. Genet. pmid:200835
McNamara DJ et al. Measurement of daily cholesterol synthesis rates in man by assay of the fractional conversion of mevalonic acid to cholesterol. 1977 Proc. Natl. Acad. Sci. U.S.A. pmid:268653
Ono T et al. Involvement of NADPH-cytochrome c reductase in the rat liver squalene epoxidase system. 1977 Biochim. Biophys. Acta pmid:403952