| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lewis RW | The squalene content of atheromatous plaques. A re-examination. | 1975 Nov-Dec | Atherosclerosis | pmid:1201156 |
| Sanina OL and Datsenko ZM | [Sterol composition of sarcolemma in normal rabbits and in experimental muscular dystrophy]. | 1975 Nov-Dec | Ukr Biokhim Zh | pmid:1202710 |
| Liu GC et al. | Measurement of cholesterol synthesis in man by isotope kinetics of squalene. | 1975 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1060141 |
| Radwan SS and Mangold HK | Lipids in plant tissue cultures. V. Effect of environmental conditions on the lipids of Glycine soja and Brassica napus cultures. | 1975 | Chem. Phys. Lipids | pmid:1168102 |
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| Teshima S and Kanazawa A | Biosynthesis of sterols in abalone, Haliotis gurneri, and mussel, Mytilus edulis. | 1974 | Comp. Biochem. Physiol., B | pmid:4452229 |
| Mas J et al. | Effect of O2, ergosterol and sterol precursors on the mating ability of Kluyveromyces lactic. | 1974 | Biochem. Biophys. Res. Commun. | pmid:4455239 |
| Johnson RC and Shah SN | Microsomal synthesis of cholesterol from squalene, Lanosterol, and desmosterol. Evidence for the presence of two noncatalytic activator proteins in the 105,000 g supernatant fraction from brain, heart, and kidney. | 1974 | Arch. Biochem. Biophys. | pmid:4460877 |
| Astruc M et al. | The binding of squalene by human placental cytosol: role in conversion of squalene to lanosterol. | 1974 | FEBS Lett. | pmid:4426400 |
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| Beck FW and Whitehouse MW | I. Drug sensitivity of rat adjuvant arthritis, induced with "adjuvants" containing no mineral oil components. | 1974 | Proc. Soc. Exp. Biol. Med. | pmid:4841187 |
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