| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ramsey RB et al. | Distribution of alkanes in normal and atherosclerotic rabbit aortas. | 1972 May-Jun | Atherosclerosis | pmid:5051654 |
| Albro PW and Fishbein L | Intestinal absorption of polychlorinated biphenyls in rats. | 1972 | Bull Environ Contam Toxicol | pmid:4630020 |
| Edgren B and Hellström K | Lipid biosynthesis from DL (2- 14 C) mevalonic acid in intact mice and rabbits. | 1972 | Acta Physiol. Scand. | pmid:4640173 |
| Cuzzopoli M et al. | Effect of nephrectomy and cholesterol feeding on the metabolism of intravenously administered DL-mevalonate in the rat. | 1972 | Metab. Clin. Exp. | pmid:4641957 |
| Mak KM and Trier JS | Radioautographic and chemical evidence for (5- 3 H)mevalonate incorporation into cholesterol by rat villous absorptive cells. | 1972 | Biochim. Biophys. Acta | pmid:4642214 |
| Dennick RG | The intracellular organisation of cholesterol biosynthesis. A review. | 1972 | Steroids Lipids Res | pmid:4572325 |
| Salen G and Polito A | Biosynthesis of 5 -cholestan-3 -ol in cerebrotendinous xanthomatosis. | 1972 | J. Clin. Invest. | pmid:4550120 |
| Rilling HC | The effect of sterol carrier protein on squalene synthesis. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400440 |
| Gaskin F and Clayton RB | An interstrain difference in cholesterol synthesis in vitro in mice, dependent upon a difference in endogenous NADPH-generating capacity. | 1972 | J. Lipid Res. | pmid:4400581 |
| Ferezou JP et al. | [On the absence of biosynthesis of sterols and squalene in coelenterata (anthozoa), the sea anemone Calliactis parasitica]. | 1972 | Experientia | pmid:4401744 |
| Ferezou JP et al. | [The absence of sterol and squalene biosynthesis a coelenterata (anthozoa), the sea anemone Calliactis parasitica]. | 1972 | Experientia | pmid:4402545 |
| Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
| Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
| Qureshi AA et al. | Lycopersene and prelycopersene pyrophosphate. Intermediates in carotene biosynthesis. | 1972 | J. Biol. Chem. | pmid:4403969 |
| Green TR and Baisted DJ | Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. | 1972 | Biochem. J. | pmid:4348263 |
| Nitchuk WM and Ainsworth L | The de novo synthesis of sterols and cholesterol from acetate-1- 14 C by sheep and pig placental and fetal liver slices in vitro. | 1972 | Steroids | pmid:5028884 |
| Mullakhanbhai MF and Francis GW | Bacterial lipids. 1. Lipid constituents of a moderately halophilic bacterium. | 1972 | Acta Chem Scand | pmid:5049648 |
| Coates RM and Robinson WH | Solvolysis of trans-2,2-dimethyl-3-(2'-methylpropenyl)cyclobutyl tosylate. Model reactions relevant to squalene biosynthesis. | 1972 | J. Am. Chem. Soc. | pmid:5053868 |
| Ainsworth L and Nitchuk WM | Cholesterol biosynthesis by sheep foetal liver and placenta in vitro. | 1972 | J. Endocrinol. | pmid:5062219 |
| Goodfellow RD and Liu GC | Squalene metabolism in the larva of the fly, Sarcophaga bullata. | 1972 | J. Insect Physiol. | pmid:5009197 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection into developing brain of (2- 14 C)mevalonic. | 1972 | J. Neurochem. | pmid:5009889 |
| Gibbons GF and Mitropoulos KA | Inhibition of cholesterol biosynthesis by carbon monoxide: accumulation of lanosterol and 24,25-dihydrolanosterol. | 1972 | Biochem. J. | pmid:5073750 |
| Edkins E and Hansen IA | Wax esters secreted by the uropygial glands of some Australian waterfowl, including the magpie goose. | 1972 | Comp. Biochem. Physiol., B | pmid:5075378 |
| Cotterill JA et al. | Age and sex variation in skin surface lipid composition and sebum excretion rate. | 1972 | Br. J. Dermatol. | pmid:5077864 |
| Slakey LL et al. | The effect of starvation and re-feeding on the rates of synthesis and degradation of enzyms effecting intermediate reactions in the synthesis of cholesterol and fatty acids in rat liver. | 1972 | Biochem. J. | pmid:5085557 |
| Ramsey RB et al. | Formation of methyl sterols in brain cholesterol biosynthesis. Sterol formation in vitro in actively myelinating rat brain. | 1972 | J. Biol. Chem. | pmid:5030627 |
| Bazzano G and Bazzano GS | Hypocholesterolemic effect of -ketoglutarate in the Mongolian gerbil. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5033114 |
| Tai HH and Bloch K | Squalene epoxidase of rat liver. | 1972 | J. Biol. Chem. | pmid:5033388 |
| Kramer JK et al. | Structure ditermination of the squalene, dihydrosqualene and tetrahydrosqualene in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5037322 |
| Kushwaha SC et al. | Isolation and identification of dehydrosqualene and C 40 -carotenoid pigments in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5038263 |
| Avigan J et al. | In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells. | 1972 | Biochim. Biophys. Acta | pmid:5041430 |
| Nicolosi RJ et al. | Lipid accumulation in muscular foci in White Carneau and Show Racer pigeon aortas. | 1972 | Exp. Mol. Pathol. | pmid:5043333 |
| Ogura K et al. | Enzymic formation of squalene homologs from farnesyl Pyrophosphate homologs. | 1972 | J. Am. Chem. Soc. | pmid:4332125 |
| Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
| Polito A et al. | Artificial substrates in squalene and sterol biosynthesis. | 1972 | J. Biol. Chem. | pmid:4337856 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Qureshi AA et al. | Squalene synthetase. I. Dissociation and reassociation of enzyme complex. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4341049 |
| Malhotra HC and Nes WR | The conversion of mevalonate to 24-methylenecycloartanol by a cell-free enzyme preparation from nonphotosynthetic tissue. | 1972 | J. Biol. Chem. | pmid:4651646 |
| Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
| Atkin SD et al. | The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. | 1972 | Biochem. J. | pmid:4655417 |
| Asakawa A et al. | The effect of nicotinamide on the cholesterol biosynthesis by cell-free rat brain extract. | 1972 | J Nihon Univ Sch Dent | pmid:4269195 |
| Cotterill JA et al. | Variations in skin surface lipid composition and sebum excretion rate with different sampling techniques. II. | 1972 | Br. J. Dermatol. | pmid:4260102 |
| Gloor M et al. | [Skin surface lipids: qualitative and quantitative determination in patients with acne vulgaris and controls. I]. | 1972 | Arch Dermatol Forsch | pmid:4260600 |
| Gloor M et al. | [Influence of skin surface lipids on the result of Burckhardt's alkali resistance determination]. | 1972 | Berufsdermatosen | pmid:4262349 |
| Cotterill JA et al. | Further observations on the pathogenesis of acne. | 1972 | Br Med J | pmid:4262616 |
| Gloor M et al. | Quantity and composition of skin surface lipids and alkaline-resistance in subjects with contact allergy and in healthy controls. | 1972 | Arch Dermatol Forsch | pmid:4264242 |
| Tronnier H | [Methodological problems in exogenous and endogenous influencing on the skin surface]. | 1972 | Arch Dermatol Forsch | pmid:4265238 |
| Singh EJ et al. | Hydrocarbons in human cervical mucus and the effect of oral contraception. | 1972 | J Reprod Med | pmid:4113025 |
| Voogt PA and Van der Horst DJ | Investigations of the capacity of synthesizing 3 -sterols in mollusca. 8. The biosynthesis of 3 -sterols in the pulmonates "Succinea putris" and "Arianta arbustorum". | 1972 | Arch. Int. Physiol. Biochim. | pmid:4114875 |
| Sipe JD and Holmlund CE | A comparison of the effects of some hypocholesteremic compounds on squalene metabolism in Tetrahymena pyriformis and rat liver. | 1972 | Biochim. Biophys. Acta | pmid:4116026 |