| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia P388 | D007941 | 43 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Lipodystrophy | D008060 | 4 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shimizu I and Katsuki H | Effect of temperature on ergosterol biosynthesis in yeast. | 1975 | J. Biochem. | pmid:1099086 |
| Ikeda U et al. | Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells. | 2000 | Hypertension | pmid:10988259 |
| Fernández-MartÃn R et al. | ent-Kaurene and squalene synthesis in Fusarium fujikuroi cell-free extracts. | 2000 | Phytochemistry | pmid:10975508 |
| Viola F et al. | Stereospecific syntheses of trans-vinyldioxidosqualene and 3-hydroxysulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors. | 2000 | Bioorg. Med. Chem. | pmid:10968281 |
| Gaber BP and Goodsell DS | The art of molecular graphics. Escape from flatland. | 2000 | J. Mol. Graph. Model. | pmid:10935209 |
| Boyce TG et al. | Safety and immunogenicity of adjuvanted and unadjuvanted subunit influenza vaccines administered intranasally to healthy adults. | 2000 | Vaccine | pmid:10930676 |
| Segura MJ et al. | Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol. | 2000 | Org. Lett. | pmid:10930257 |
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| Newmark HL | Is oleic acid or squalene the important preventive agent? | 2000 | Am. J. Clin. Nutr. | pmid:10919949 |
| Nurminen T et al. | Neutral lipids in the cells and cell envelope fractions of aerobic baker's yeast and anaerobic brewer's yeast. | 1975 | Chem. Phys. Lipids | pmid:1091369 |
| Owen RW et al. | Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene. | 2000 | Food Chem. Toxicol. | pmid:10908812 |
| Maes D et al. | Noninvasive techniques for measuring oxidation products on the surface of human skin. | 2000 | Meth. Enzymol. | pmid:10907548 |
| Nakano M et al. | 3-(4'-methyl-1'-naphthyl)propionic acid, 1',4'-endoperoxide for dioxygenation of squalene and for bacterial killing. | 2000 | Meth. Enzymol. | pmid:10907513 |
| Kohashi O and Pearson CM | Arthritogenicity of Mycobacterium smegmatis subfractions, related to different oil vehicle and different composition. | 1976 | Int. Arch. Allergy Appl. Immunol. | pmid:1085757 |
| Carlson BC et al. | The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. | 2000 | Am. J. Pathol. | pmid:10854227 |
| Chiba K et al. | Comedogenicity of squalene monohydroperoxide in the skin after topical application. | 2000 | J Toxicol Sci | pmid:10845185 |
| Rhodes CJ et al. | "Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition. | 2000 | Free Radic. Res. | pmid:10826923 |
| Alving CR and Grabenstein JD | Re: Antibodies to squalene in Gulf War Syndrome. | 2000 | Exp. Mol. Pathol. | pmid:10816387 |
| Viola F et al. | Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase. | 2000 | Lipids | pmid:10783007 |
| Relas H et al. | Effect of stanol ester on postabsorptive squalene and retinyl palmitate. | 2000 | Metab. Clin. Exp. | pmid:10778871 |