(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Demyelinating Diseases D003711 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Rosacea D012393 13 associated lipids
Keloid D007627 12 associated lipids
Otitis Media D010033 12 associated lipids
Dermatitis, Occupational D009783 12 associated lipids
Influenza, Human D007251 11 associated lipids
Hepatitis D006505 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Burkhart CN et al. Cerumen composition by flash pyrolysis-gas chromatography/mass spectrometry. 2001 Otol. Neurotol. pmid:11698786
Milla P et al. Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles. 2002 J. Biol. Chem. pmid:11706015
Sawada M et al. Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells. 2001 Eur. J. Pharmacol. pmid:11716837
Simonen P et al. Acute effects of weight reduction on cholesterol metabolism in obese type 2 diabetes. 2002 Clin. Chim. Acta pmid:11750274
He HP et al. Extraction and purification of squalene from amaranthus grain. 2002 J. Agric. Food Chem. pmid:11782209
Haralampidis K et al. Biosynthesis of triterpenoid saponins in plants. 2002 Adv. Biochem. Eng. Biotechnol. pmid:11783842
Corcelli A et al. Lipid-protein stoichiometries in a crystalline biological membrane: NMR quantitative analysis of the lipid extract of the purple membrane. 2002 J. Lipid Res. pmid:11792732
Saadatzadeh MR et al. Production of the mycelial phase of Malassezia in vitro. 2001 Med. Mycol. pmid:11798054
Psomiadou E and Tsimidou M Stability of virgin olive oil. 1. Autoxidation studies. 2002 J. Agric. Food Chem. pmid:11829634
Psomiadou E and Tsimidou M Stability of virgin olive oil. 2. Photo-oxidation studies. 2002 J. Agric. Food Chem. pmid:11829635