| MeSH term | MeSH ID | Detail |
|---|---|---|
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Hepatitis | D006505 | 11 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Scalp Dermatoses | D012536 | 11 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mercer EI | Inhibitors of sterol biosynthesis and their applications. | 1993 | Prog. Lipid Res. | pmid:8309949 |
| Phleger CF et al. | Membrane biosynthesis in swimbladders of deep sea fishes Coryphaenoides acrolepis and Antimora rostrata. | 1977 | Comp. Biochem. Physiol., B | pmid:830467 |
| Florin-Christensen M et al. | Occurrence of specific sterols in Pneumocystis carinii. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8292026 |
| Ernst J et al. | The crystal structure of squalene. | 1976 | Angew. Chem. Int. Ed. Engl. | pmid:827944 |
| Balliano G et al. | 3-Carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase. | 1993 | Lipids | pmid:8246689 |
| Vanhanen HT et al. | Serum cholesterol, cholesterol precursors, and plant sterols in hypercholesterolemic subjects with different apoE phenotypes during dietary sitostanol ester treatment. | 1993 | J. Lipid Res. | pmid:8228636 |
| Ciosek CP et al. | Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo. | 1993 | J. Biol. Chem. | pmid:8227045 |
| Beck FW and Whitehouse MW | Modifications in the establishment of allergic encephalomyelitis (EAE) in rats; an imporved assay for immunosuppressant drugs. | 1976 | Agents Actions | pmid:822699 |
| Corsini A et al. | Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. | 1993 | Atherosclerosis | pmid:8216498 |
| Ohkawa S et al. | Immune responses induced by prototype vaccines for AIDS in rhesus monkeys. | 1994 | AIDS Res. Hum. Retroviruses | pmid:8179961 |