| MeSH term | MeSH ID | Detail |
|---|---|---|
| Demyelinating Diseases | D003711 | 15 associated lipids |
| Hyperlipoproteinemias | D006951 | 15 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Keloid | D007627 | 12 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Influenza, Human | D007251 | 11 associated lipids |
| Hepatitis | D006505 | 11 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Scalp Dermatoses | D012536 | 11 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rilling HC | The effect of sterol carrier protein on squalene synthesis. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4400440 |
| Scallen TJ et al. | Studies on the enzymatic synthesis of cholesterol: use of a liver acetone powder. | 1971 | Lipids | pmid:4396848 |
| Fiser RH et al. | Effects of acute infection on cholesterogenesis in the rhesus monkey. | 1971 | Proc. Soc. Exp. Biol. Med. | pmid:4399094 |
| Edmond J et al. | Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. | 1971 | J. Biol. Chem. | pmid:4399596 |
| Ferne M et al. | [Isolation and characterization of various membrane fractions type active in the synthesis in vitro of squalene and obtained from anergic tissue cultures of tobacco]. | 1971 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:4997022 |
| Nes WR | Regulation of the sequencing in sterol biosynthesis. | 1971 | Lipids | pmid:4997338 |
| Anding C et al. | Sterol biosynthesis in Euglena gracilis Z. Sterol precursors in light-grown and dark-grown Euglena gracilis Z. | 1971 | Eur. J. Biochem. | pmid:5003307 |
| Dean PD | The cyclases of triterpene and sterol biosynthesis. | 1971 | Steroidologia | pmid:5004310 |
| Shamberger RJ | Inhibitory effect of vitamin A on carcinogenesis. | 1971 | J. Natl. Cancer Inst. | pmid:5157584 |
| Bird CW et al. | Steroids and squalene in Methylococcus capsulatus grown on methane. | 1971 | Nature | pmid:4929985 |
| van Leusden HA et al. | Squalene and lanosterol synthesis in the foeto-placental unit at midgestation. | 1971 | Acta Endocrinol. | pmid:5108099 |
| Oesch F et al. | Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes. | 1971 | Arch. Biochem. Biophys. | pmid:5117530 |
| Woods RA | Nystatin-resistant mutants of yeast: alterations in sterol content. | 1971 | J. Bacteriol. | pmid:5122815 |
| Popják G | Specificity of enzymes of sterol biosynthesis. | 1971 | Harvey Lect. | pmid:5123650 |
| Smith AG and Goad LJ | Sterol biosynthesis in the starfish Asterias rubens and Henricia sanguinolenta. | 1971 | Biochem. J. | pmid:5126917 |
| Ramsey RB et al. | Squalene-like isoprenoid hydrocarbons in bovine brain. | 1971 | J. Neurochem. | pmid:5129357 |
| Taylor RF and Ikawa M | Gas chromatography of carotenoids. | 1971 | Anal. Biochem. | pmid:5130948 |
| Boguslawski W and Zelewski L | Inhibition of cholesterol biosynthesis by the respiratory chain inhibitors in human placenta and in rat liver. | 1971 | Biochem. Pharmacol. | pmid:5132889 |
| Wells JW | Steroids in the pineal gland of the domestic fowl (Gallus domesticus): cholesterol and its biosynthesis. | 1971 | Comp. Biochem. Physiol., B | pmid:5133342 |
| van Tamelen EE et al. | Formation of A-B cis- and trans-19-norlanosterols by enzymic cyclization of 6'-norsqualene 2,3-oxide. | 1971 | J. Am. Chem. Soc. | pmid:5135874 |
| Chida N and Okamura T | Increased cholesterol-biosynthesis in familial hypercholesterolemia. | 1971 | Tohoku J. Exp. Med. | pmid:5140375 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. Distribution in subcellular fractions as a function of time after intracerebral injection of [2-14C]-mevalonic acid. | 1971 | J. Neurochem. | pmid:5092868 |
| Mallory FB and Conner RL | Dehydrogenation and dealkylation of various sterols by Tetrahymena pyriformis. | 1971 | Lipids | pmid:4102490 |
| Goodwin TW | Biosynthesis of carotenoids and plant triterpenes. | 1971 | Biochem. J. | pmid:4331177 |
| Bloxham DP and Akhtar M | Studies on the control of cholesterol biosynthesis: the adenosine 3':5'-cyclic monophosphate-dependent accumulation of a steroid carboxylic acid. | 1971 | Biochem. J. | pmid:4331371 |
| Green TR and Baisted DJ | Development of the squalene-synthesizing system during early stages of pea seed germination. | 1971 | Biochem. J. | pmid:4335540 |
| Tamelen EE and Schwartz MA | Mechanism of presqualene pyrophosphate-squalene biosynthesis. | 1971 | J. Am. Chem. Soc. | pmid:4323745 |
| Rilling HC et al. | Studies on the mechanism of squalene biosynthesis. Presqualene pyrophosphate, stereochemistry and a mechanism for its conversion to squalene. | 1971 | J. Am. Chem. Soc. | pmid:4323746 |
| Cotterill JA et al. | Sebum excretion rate and biochemistry in patients with acne vulgaris treated by oral fenfluramine. | 1971 | Br. J. Dermatol. | pmid:4255130 |
| Cotterill JA et al. | The effect of trimethoprim-sulphamethoxazole on sebum excretion rate and biochemistry in acne vulgaris. | 1971 | Br. J. Dermatol. | pmid:4255131 |
| Summerly R and Woodbury S | The in vitro incorporation of 14 C-acetate into the isolated sebaceous glands and appendage-freed epidermis of human skin. A technique for the study of lipid synthesis in the isolated sebaceous gland. | 1971 | Br. J. Dermatol. | pmid:4257140 |
| Cuncliffe WJ et al. | Skin surface lipids in acne. | 1971 | Br. J. Dermatol. | pmid:4257142 |
| Mulheirn LJ and Caspi E | Mechanism of squalene cyclization. The biosynthesis of fusidic acid. | 1971 | J. Biol. Chem. | pmid:5553407 |
| Cotterill JA et al. | A semiquantitative method for the biochemical analysis of sebum. | 1971 | Br. J. Dermatol. | pmid:5557832 |
| Cunliffe WJ et al. | Variations in skin surface lipid composition with different sampling techniques. I. | 1971 | Br. J. Dermatol. | pmid:5557833 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. II. A comparison of in vitro and in vivo methods. | 1971 | Lipids | pmid:5559874 |
| Peter G et al. | [Gas-chromatography studies on sebaceous gland lipids. II. Composition of sebaceous gland lipids in various age groups]. | 1971 | Arch Dermatol Forsch | pmid:5560856 |
| Peter G and Peter R | [Studies on the composition of palmar skin surface fat in relation to age and its biochemical bases]. | 1971 | Arch Dermatol Forsch | pmid:5571755 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. I. Subcellular biosynthesis in vitro. | 1971 | Lipids | pmid:5574907 |
| Daly MM | Biosynthesis of squalene and sterols by rat aorta. | 1971 | J. Lipid Res. | pmid:5579265 |
| Aaronson S | Inhibition of yeast multiplication by hypocholesteremic compounds and its annulment by lipids. | 1971 | Proc. Soc. Exp. Biol. Med. | pmid:5540639 |
| Corey EJ et al. | Conversion of des-6-methyl-2,3-oxidosqualene to 19-norlanosterol by 2,3-oxidosqualene-sterol cyclase. | 1971 | J. Am. Chem. Soc. | pmid:5548348 |
| Altman LJ et al. | Synthesis and conversion of presqualene alcohol to squalene. | 1971 | J. Am. Chem. Soc. | pmid:5550251 |
| Coates RM and Robinson WH | Stereoselective total synthesis of (plus or minus)-presqualene alcohol. | 1971 | J. Am. Chem. Soc. | pmid:5550252 |
| Jones JP et al. | Lipid biosynthesis in neuron-enriched and glial-enriched fractions of rat brain: sterol formation. | 1971 | Life Sci. II | pmid:5569686 |
| Malhotra HC and Nes WR | The mechanism of introduction of alkyl groups at C-24 of sterols. IV. Inhibition by triparanol. | 1971 | J. Biol. Chem. | pmid:5570429 |
| Habczyńska D et al. | [The effect of squalene and cholesterol on the histological picture of the periodontium in white rats]. | 1970 Oct-Nov | Czas Stomatol | pmid:5274119 |
| Stefanovich V and Kajiyama G | Squalene and cholestanol in normal rabbit aorta. | 1970 May-Jun | Atherosclerosis | pmid:5433085 |
| Rilling HC | Biosynthesis of presqualene pyrophosphate by liver microsomes. | 1970 | J. Lipid Res. | pmid:4322765 |
| Sloviter HA et al. | Biosynthesis of cholesterol in rabbit reticulocytes and its exchange with plasma. | 1970 | J. Lipid Res. | pmid:5418482 |