| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Ossification, Heterotopic | D009999 | 2 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Parvoviridae Infections | D010322 | 4 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vanhanen HT and Miettinen TA | Cholesterol absorption and synthesis during pravastatin, gemfibrozil and their combination. | 1995 | Atherosclerosis | pmid:7661873 |
| Gylling H et al. | Postprandial vitamin A and squalene clearances and cholesterol synthesis off and on lovastatin treatment in type III hyperlipoproteinemia. | 1995 | Atherosclerosis | pmid:7669084 |
| Kerwin JL et al. | Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum. | 1995 | Microbiology (Reading, Engl.) | pmid:7704271 |
| Fliesler SJ et al. | Isoprenoid lipid metabolism in the retina: dynamics of squalene and cholesterol incorporation and turnover in frog rod outer segment membranes. | 1995 | Exp. Eye Res. | pmid:7720806 |
| Houston L et al. | Response of guinea pigs to a vaccine containing a new adjuvant (SAF) and gram-negative bacteria. | 1995 | Lab. Anim. Sci. | pmid:7752616 |
| Langenberg AG et al. | A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]. | 1995 | Ann. Intern. Med. | pmid:7755223 |
| Yamamoto A et al. | Impaired water barrier function in acne vulgaris. | 1995 | Arch. Dermatol. Res. | pmid:7763094 |
| Kamimura N et al. | Construction of squalene-accumulating Saccharomyces cerevisiae mutants by gene disruption through homologous recombination. | 1994 | Appl. Microbiol. Biotechnol. | pmid:7765777 |
| Lees ND et al. | Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. | 1995 | Lipids | pmid:7791529 |
| Abe I and Prestwich GD | Identification of the active site of vertebrate oxidosqualene cyclase. | 1995 | Lipids | pmid:7791531 |
| Cattel L et al. | 2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. | 1995 | Lipids | pmid:7791532 |
| Balliano G et al. | Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. | 1994 | Antimicrob. Agents Chemother. | pmid:7810997 |
| Rabiskova M et al. | The influence of surface properties on uptake of oil into complex coacervate microcapsules. | 1994 | J. Pharm. Pharmacol. | pmid:7815274 |
| Someya K et al. | The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. | 1994 | J. Nutr. Sci. Vitaminol. | pmid:7844638 |
| Fujita H and Matsuo I | In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. | 1994 | Photodermatol Photoimmunol Photomed | pmid:7880759 |
| Boutaud O et al. | Retention of the label during the conversion of [3-3H] squalene into (3S)-2,3-oxidosqualene catalyzed by mammalian squalene oxidase. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7887959 |
| Coates RM | Biogenetic-type rearrangements of terpenes. | 1976 | Fortschr Chem Org Naturst | pmid:791779 |
| Valensi JP et al. | Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants. | 1994 | J. Immunol. | pmid:7930610 |
| Kahn JO et al. | Clinical and immunologic responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers. | 1994 | J. Infect. Dis. | pmid:7963729 |
| Hoffman SL et al. | Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant. | 1994 | Am. J. Trop. Med. Hyg. | pmid:7985753 |