| MeSH term | MeSH ID | Detail |
|---|---|---|
| Niemann-Pick Diseases | D009542 | 25 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Ossification, Heterotopic | D009999 | 2 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Parvoviridae Infections | D010322 | 4 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Langenberg AG et al. | A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]. | 1995 | Ann. Intern. Med. | pmid:7755223 |
| Houston L et al. | Response of guinea pigs to a vaccine containing a new adjuvant (SAF) and gram-negative bacteria. | 1995 | Lab. Anim. Sci. | pmid:7752616 |
| Fliesler SJ et al. | Isoprenoid lipid metabolism in the retina: dynamics of squalene and cholesterol incorporation and turnover in frog rod outer segment membranes. | 1995 | Exp. Eye Res. | pmid:7720806 |
| Kerwin JL et al. | Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum. | 1995 | Microbiology (Reading, Engl.) | pmid:7704271 |
| Gylling H et al. | Postprandial vitamin A and squalene clearances and cholesterol synthesis off and on lovastatin treatment in type III hyperlipoproteinemia. | 1995 | Atherosclerosis | pmid:7669084 |
| Vanhanen HT and Miettinen TA | Cholesterol absorption and synthesis during pravastatin, gemfibrozil and their combination. | 1995 | Atherosclerosis | pmid:7661873 |
| Pittler SJ et al. | In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure. | 1995 | J. Cell Biol. | pmid:7615641 |
| Nagumo A et al. | Purification and characterization of recombinant squalene epoxidase. | 1995 | J. Lipid Res. | pmid:7595073 |
| Viola F et al. | Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. | 1995 | Biochem. Pharmacol. | pmid:7575639 |
| Ott G et al. | MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. | 1995 | Pharm Biotechnol | pmid:7551221 |
| Yoshino S and Yoshino J | Recruitment of pathogenic T cells to synovial tissues of rats injected intraarticularly with nonspecific agents. | 1994 | Cell. Immunol. | pmid:7522973 |
| PerederiÄ OF and Morozova RP | [Squalene and sterols of rat stomach tissue and the effect of acetylsalicylic acid on their content]. | 1978 Nov-Dec | Ukr. Biokhim. Zh. | pmid:749299 |
| Lewis D et al. | Enzyme inhibition during the conversion of squalene to cholesterol. | 1995 | Steroids | pmid:7482633 |
| Robuccio JA et al. | Comparison of the effects of five adjuvants on the antibody response to influenza virus antigen in guinea pigs. | 1995 | Lab. Anim. Sci. | pmid:7474883 |
| Soloway AH and LeQuesne PW | Potential endogenous mutagens/carcinogens. | 1980 | J. Theor. Biol. | pmid:7464159 |
| Morin RJ and Srikantaiah MV | In vitro conversion of squalene from squalene-phospholipid liposomes into sterols by rat liver microsomes and cytosol. | 1980 | J. Lipid Res. | pmid:7462811 |
| Rohmer M et al. | Non-specific biosynthesis of hopane triterpenes by a cell-free system from Acetobacter pasteurianum. | 1980 | Eur. J. Biochem. | pmid:7460938 |
| Nelson JA et al. | Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. | 1981 | J. Biol. Chem. | pmid:7451488 |
| Srikantaiah MV et al. | Inhibition of rat hepatic sterol formation from squalene by plasma lipoproteins. | 1980 | Lipids | pmid:7432102 |
| Matsumoto G and Hanya T | Presence of squalane in urban aquatic environments. | 1980 | J. Chromatogr. | pmid:7410506 |