| MeSH term | MeSH ID | Detail |
|---|---|---|
| Precancerous Conditions | D011230 | 48 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Radisky ES and Poulter CD | Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies. | 2000 | Biochemistry | pmid:10677224 |
| Sporn MB and Suh N | Chemoprevention of cancer. | 2000 | Carcinogenesis | pmid:10688873 |
| O'Hagan DT et al. | Microparticles in MF59, a potent adjuvant combination for a recombinant protein vaccine against HIV-1. | 2000 | Vaccine | pmid:10699327 |
| Moebius FF et al. | Genetic defects in postsqualene cholesterol biosynthesis. | 2000 | Trends Endocrinol. Metab. | pmid:10707051 |
| Drulak MW et al. | Vaccination of seropositive subjects with CHIRON CMV gB subunit vaccine combined with MF59 adjuvant for production of CMV immune globulin. | 2000 | Viral Immunol. | pmid:10733168 |
| Rajaratnam RA et al. | Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women. | 2000 | J. Am. Coll. Cardiol. | pmid:10758959 |
| Relas H et al. | Effect of stanol ester on postabsorptive squalene and retinyl palmitate. | 2000 | Metab. Clin. Exp. | pmid:10778871 |
| Viola F et al. | Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase. | 2000 | Lipids | pmid:10783007 |
| Alving CR and Grabenstein JD | Re: Antibodies to squalene in Gulf War Syndrome. | 2000 | Exp. Mol. Pathol. | pmid:10816387 |
| Rhodes CJ et al. | "Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition. | 2000 | Free Radic. Res. | pmid:10826923 |
| Chiba K et al. | Comedogenicity of squalene monohydroperoxide in the skin after topical application. | 2000 | J Toxicol Sci | pmid:10845185 |
| Carlson BC et al. | The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. | 2000 | Am. J. Pathol. | pmid:10854227 |
| Kohashi O and Pearson CM | Arthritogenicity of Mycobacterium smegmatis subfractions, related to different oil vehicle and different composition. | 1976 | Int. Arch. Allergy Appl. Immunol. | pmid:1085757 |
| Nakano M et al. | 3-(4'-methyl-1'-naphthyl)propionic acid, 1',4'-endoperoxide for dioxygenation of squalene and for bacterial killing. | 2000 | Meth. Enzymol. | pmid:10907513 |
| Maes D et al. | Noninvasive techniques for measuring oxidation products on the surface of human skin. | 2000 | Meth. Enzymol. | pmid:10907548 |
| Owen RW et al. | Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene. | 2000 | Food Chem. Toxicol. | pmid:10908812 |
| Nurminen T et al. | Neutral lipids in the cells and cell envelope fractions of aerobic baker's yeast and anaerobic brewer's yeast. | 1975 | Chem. Phys. Lipids | pmid:1091369 |
| Newmark HL | Is oleic acid or squalene the important preventive agent? | 2000 | Am. J. Clin. Nutr. | pmid:10919949 |
| Romera SA et al. | Adjuvant effects of sulfolipo-cyclodextrin in a squalane-in-water and water-in-mineral oil emulsions for BHV-1 vaccines in cattle. | 2000 | Vaccine | pmid:10924795 |
| Segura MJ et al. | Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol. | 2000 | Org. Lett. | pmid:10930257 |