Sotiroudis TG and Kyrtopoulos SA |
Anticarcinogenic compounds of olive oil and related biomarkers. |
2008 |
Eur J Nutr |
pmid:18458836
|
Stella B et al. |
Nonpolymeric nanoassemblies for ocular administration of acyclovir: pharmacokinetic evaluation in rabbits. |
2012 |
Eur J Pharm Biopharm |
pmid:22008147
|
Chen CC et al. |
Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics. |
2010 |
Eur J Pharm Biopharm |
pmid:20060469
|
Bildstein L et al. |
Interaction of an amphiphilic squalenoyl prodrug of gemcitabine with cellular membranes. |
2011 |
Eur J Pharm Biopharm |
pmid:21784150
|
Lee JS et al. |
Exogenous lipoid pneumonia: high-resolution CT findings. |
1999 |
Eur Radiol |
pmid:10101652
|
Ochs D et al. |
Properties of purified squalene-hopene cyclase from Bacillus acidocaldarius. |
1990 |
Eur. J. Biochem. |
pmid:2253626
|
Cornforth JW et al. |
Substrate stereochemistry of 3-hydroxy-3-methylglutaryl-coenzyme A synthase. |
1974 |
Eur. J. Biochem. |
pmid:4597848
|
Parks LW et al. |
Sterol transmethylation during aerobic adaptation of yeast. |
1974 |
Eur. J. Biochem. |
pmid:4598750
|
Kribii R et al. |
Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase--involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway. |
1997 |
Eur. J. Biochem. |
pmid:9363754
|
Anding C et al. |
Sterol biosynthesis in Euglena gracilis Z. Sterol precursors in light-grown and dark-grown Euglena gracilis Z. |
1971 |
Eur. J. Biochem. |
pmid:5003307
|
Kushiro T et al. |
Beta-amyrin synthase--cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants. |
1998 |
Eur. J. Biochem. |
pmid:9746369
|
Phillips GT and Ross FP |
Stereochemistry of C-1,2-dehydrogenation during cholesterol degradation by Mycobacterium phlei. |
1974 |
Eur. J. Biochem. |
pmid:4838683
|
Bouvier P et al. |
Non-specific biosynthesis of gammacerane derivatives by a cell-free system from the protozoon Tetrahymena pyriformis. Conformations of squalene, (3S)-squalene epoxide and (3R)-squalene epoxide during the cyclization. |
1980 |
Eur. J. Biochem. |
pmid:6780347
|
Rohmer M et al. |
Non-specific lanosterol and hopanoid biosynthesis be a cell-free system from the bacterium Methylococcus capsulatus. |
1980 |
Eur. J. Biochem. |
pmid:6780348
|
Eneroth P et al. |
Steroids in newborns and infants. Identification of 24,25-dihydro-delta-9(ll)-lanosterol and 4 alpha, 14 alpha-dimethyl substituted sterols among the esterified and free sterols in human meconium. |
1969 |
Eur. J. Biochem. |
pmid:5368336
|
Goad LJ and Goodwin TW |
Studies in phytosterol biosynthesis: observations on the biosynthesis of fucosterol in the marine brown alga Fucus spiralis. |
1969 |
Eur. J. Biochem. |
pmid:5780485
|
Eppenberger U et al. |
[Anerobic cyclization of squalen-2,3-epoxide to cycloartenol in Nicotiana tabacum L. tissue cultures]. |
1969 |
Eur. J. Biochem. |
pmid:5781271
|
Dada OA et al. |
Biosynthesis of phytoquinones. Stereospecific biosynthesis of the polyprenyl side chains of terpenoid quinones and chromanols in maize shoots. |
1968 |
Eur. J. Biochem. |
pmid:5653765
|
Rohmer M et al. |
Non-specific biosynthesis of hopane triterpenes by a cell-free system from Acetobacter pasteurianum. |
1980 |
Eur. J. Biochem. |
pmid:7460938
|
Moreau JP et al. |
Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. |
1975 |
Eur. J. Biochem. |
pmid:1100393
|
Hendler RW et al. |
Purple membrane lipid control of bacteriorhodopsin conformational flexibility and photocycle activity. |
2003 |
Eur. J. Biochem. |
pmid:12709050
|
Das B et al. |
In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity. implications in cancer chemotherapy. |
2003 |
Eur. J. Cancer |
pmid:14602142
|
Khallouki F et al. |
Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects. |
2003 |
Eur. J. Cancer Prev. |
pmid:12548113
|
Miettinen TA and Gylling H |
Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose of statin treatment. |
2003 |
Eur. J. Clin. Invest. |
pmid:14636301
|
Miettinen TA |
Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. |
1980 |
Eur. J. Clin. Invest. |
pmid:6768564
|
Gylling H et al. |
Effects of acipimox and cholestyramine on serum lipoproteins, non-cholesterol sterols and cholesterol absorption and elimination. |
1989 |
Eur. J. Clin. Pharmacol. |
pmid:2792164
|
Gloor M and Kohler H |
A contribution to a new test method for dandruff-inhibiting and "keratolytic" action of drugs. |
1977 |
Eur. J. Clin. Pharmacol. |
pmid:880976
|
Gasparini R et al. |
Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects. |
2001 |
Eur. J. Epidemiol. |
pmid:11599686
|
Tomasi M et al. |
Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. |
1997 |
Eur. J. Immunol. |
pmid:9368632
|
Dupuis M et al. |
Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis. |
2001 |
Eur. J. Immunol. |
pmid:11592066
|
Lippi G et al. |
Vaccination, squalene and anti-squalene antibodies: facts or fiction? |
2010 |
Eur. J. Intern. Med. |
pmid:20206873
|
Sawada M et al. |
Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells. |
2001 |
Eur. J. Pharmacol. |
pmid:11716837
|
Wepierre J et al. |
Percutaneous absorption and removal by the body fluids of 14C ethyl alcohol, 3H perhydrosqualene and 14C p-cymene. |
1968 |
Eur. J. Pharmacol. |
pmid:5654669
|
Gonzalez R et al. |
Studies of sterol synthesis, synthesis regulation and transport in cultured human kidney. |
1974 |
Exp. Cell Res. |
pmid:4841900
|
Chen JK et al. |
Biochemical characterization of the cholesterol-dependent growth of the NS-1 mouse myeloma cell line. |
1986 |
Exp. Cell Res. |
pmid:3943557
|
Chiba K et al. |
Skin roughness and wrinkle formation induced by repeated application of squalene-monohydroperoxide to the hairless mouse. |
1999 |
Exp. Dermatol. |
pmid:10597136
|
Tachi M and Iwamori M |
Mass spectrometric characterization of cholesterol esters and wax esters in epidermis of fetal, adult and keloidal human skin. |
2008 |
Exp. Dermatol. |
pmid:17979971
|
Hayashi N et al. |
Effect of sunlight exposure and aging on skin surface lipids and urate. |
2003 |
Exp. Dermatol. |
pmid:14756518
|
Tiffany JM |
Individual variations in human meibomian lipid composition. |
1978 |
Exp. Eye Res. |
pmid:710541
|
Fliesler SJ et al. |
Squalene is localized to the plasma membrane in bovine retinal rod outer segments. |
1997 |
Exp. Eye Res. |
pmid:9176062
|
Cenedella RJ |
Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols. |
1997 |
Exp. Eye Res. |
pmid:9237866
|
Fliesler SJ et al. |
Isoprenoid lipid metabolism in the retina: dynamics of squalene and cholesterol incorporation and turnover in frog rod outer segment membranes. |
1995 |
Exp. Eye Res. |
pmid:7720806
|
Aguilera Y et al. |
The protective role of squalene in alcohol damage in the chick embryo retina. |
2005 |
Exp. Eye Res. |
pmid:15781281
|
Takeuchi N et al. |
Impairment of hepatic cholesterol synthesis from squalene and the function of hepatic sterol carrier protein system by ageing. |
1978 |
Exp. Gerontol. |
pmid:639893
|
Bell FP |
Biosynthesis of various sterols, sterol esters, and squalene from [14C]mevalonate by normal swine intima and media in vitro: a comparative study. |
1976 |
Exp. Mol. Pathol. |
pmid:1001402
|
Asa PB et al. |
Antibodies to squalene in Gulf War syndrome. |
2000 |
Exp. Mol. Pathol. |
pmid:10640454
|
Alving CR and Grabenstein JD |
Re: Antibodies to squalene in Gulf War Syndrome. |
2000 |
Exp. Mol. Pathol. |
pmid:10816387
|
Lofland HB et al. |
Atherosclerosis in Cebus monkeys. II. Arterial metabolism. |
1968 |
Exp. Mol. Pathol. |
pmid:4969998
|
Nicolosi RJ et al. |
Lipid accumulation in muscular foci in White Carneau and Show Racer pigeon aortas. |
1972 |
Exp. Mol. Pathol. |
pmid:5043333
|
St Clair RW et al. |
Synthesis of squalene and sterols by isolated segments of human and pigeon arteries. |
1968 |
Exp. Mol. Pathol. |
pmid:5647248
|
Asa PB et al. |
Antibodies to squalene in recipients of anthrax vaccine. |
2002 |
Exp. Mol. Pathol. |
pmid:12127050
|
Gajkowska B et al. |
The experimental squalene encephaloneuropathy in the rat. |
1999 |
Exp. Toxicol. Pathol. |
pmid:10048717
|
Bose AK and Hungund BL |
The role of glycine in the biosynthesis of steroids. |
1973 |
Experientia |
pmid:4582087
|
Grob EC and Csupor L |
[Information on the leaf lipids of Acer platanoides L. during autumn yellowing]. |
1967 |
Experientia |
pmid:6077859
|
Ferezou JP et al. |
[On the absence of biosynthesis of sterols and squalene in coelenterata (anthozoa), the sea anemone Calliactis parasitica]. |
1972 |
Experientia |
pmid:4401744
|
Ferezou JP et al. |
[The absence of sterol and squalene biosynthesis a coelenterata (anthozoa), the sea anemone Calliactis parasitica]. |
1972 |
Experientia |
pmid:4402545
|
el-Ibrashy MT and Mansour MH |
Hormonal action of certain biologically active compounds in Agrotis ypsilon larvae. |
1970 |
Experientia |
pmid:5483755
|
Gower DB et al. |
Axillary 5 alpha-androst-16-en-3-one in men and women: relationships with olfactory acuity to odorous 16-androstenes. |
1985 |
Experientia |
pmid:4043321
|
Durando P et al. |
MF59-adjuvanted vaccine: a safe and useful tool to enhance and broaden protection against seasonal influenza viruses in subjects at risk. |
2010 |
Expert Opin Biol Ther |
pmid:20218923
|
Celia C et al. |
Gemcitabine-loaded innovative nanocarriers vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity. |
2011 |
Expert Opin Drug Deliv |
pmid:22077480
|
Smith TJ |
Squalene: potential chemopreventive agent. |
2000 |
Expert Opin Investig Drugs |
pmid:11060781
|
Vera-Lastra O et al. |
Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum. |
2013 |
Expert Rev Clin Immunol |
pmid:23557271
|
Podda A and Del Giudice G |
MF59-adjuvanted vaccines: increased immunogenicity with an optimal safety profile. |
2003 |
Expert Rev Vaccines |
pmid:12899571
|
Gasparini R et al. |
Aflunov(®): a prepandemic influenza vaccine. |
2012 |
Expert Rev Vaccines |
pmid:22309663
|
Puig-Barberà J et al. |
MF59â„¢-adjuvanted seasonal influenza vaccine in young children. |
2011 |
Expert Rev Vaccines |
pmid:22043952
|
Garçon N et al. |
Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion. |
2012 |
Expert Rev Vaccines |
pmid:22380826
|
Rappuoli R |
Vaccine adjuvants: the future is bright. Interview by Jenaid Rees. |
2013 |
Expert Rev Vaccines |
pmid:23829664
|
Puig Barberà J and González Vidal D |
MF59-adjuvanted subunit influenza vaccine: an improved interpandemic influenza vaccine for vulnerable populations. |
2007 |
Expert Rev Vaccines |
pmid:17931147
|
O'Hagan DT |
MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection. |
2007 |
Expert Rev Vaccines |
pmid:17931151
|
Fox CB and Haensler J |
An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants. |
2013 |
Expert Rev Vaccines |
pmid:23885820
|
O'Hagan DT et al. |
The history of MF59(®) adjuvant: a phoenix that arose from the ashes. |
2013 |
Expert Rev Vaccines |
pmid:23256736
|
Walker WT and Faust SN |
Monovalent inactivated split-virion AS03-adjuvanted pandemic influenza A (H1N1) vaccine. |
2010 |
Expert Rev Vaccines |
pmid:21105775
|
O'Hagan DT et al. |
MF59 adjuvant: the best insurance against influenza strain diversity. |
2011 |
Expert Rev Vaccines |
pmid:21506643
|
El Sahly H |
MF59™ as a vaccine adjuvant: a review of safety and immunogenicity. |
2010 |
Expert Rev Vaccines |
pmid:20923265
|
Viola F et al. |
22,23-Epoxy-2-aza-2,3-dihydrosqualene derivatives: potent new inhibitors of squalene 2,3-oxide-lanosterol cyclase. |
1990 |
Farmaco |
pmid:2282128
|
Saenz MT et al. |
Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil. |
1998 |
Farmaco |
pmid:9786644
|
Cherkes AI and Klebanov BM |
[Cholesterine synthesis as an object of the action of drugs. (Review of the literature)]. |
1966 Nov-Dec |
Farmakol Toksikol |
pmid:6000378
|
Ito R et al. |
Purification, kinetics, inhibitors and CD for recombinant β-amyrin synthase from Euphorbia tirucalli L and functional analysis of the DCTA motif, which is highly conserved among oxidosqualene cyclases. |
2013 |
FEBS J. |
pmid:23294602
|
Ta MT et al. |
Accumulation of squalene is associated with the clustering of lipid droplets. |
2012 |
FEBS J. |
pmid:23013491
|
Astruc M et al. |
The binding of squalene by human placental cytosol: role in conversion of squalene to lanosterol. |
1974 |
FEBS Lett. |
pmid:4426400
|
Furubayashi M et al. |
Directed evolution of squalene synthase for dehydrosqualene biosynthesis. |
2014 |
FEBS Lett. |
pmid:25093296
|
Ryder NS et al. |
Inhibition of fungal and mammalian sterol biosynthesis by 2-aza-2,3-dihydrosqualene. |
1986 |
FEBS Lett. |
pmid:3525224
|
Nakano M et al. |
Useful 1O2 (1delta g) generator, 3-(4'-methyl-1'-naphthyl)-propionic acid, 1',4'-endoperoxide (NEPO), for dioxygenation of squalence (a skin surface lipid) in an organic solvent and bacterial killing in aqueous medium. |
1998 |
FEBS Lett. |
pmid:9710240
|
Balliano G et al. |
Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene. |
1993 |
FEBS Lett. |
pmid:8462686
|
Dracheva S et al. |
Chemical and functional studies on the importance of purple membrane lipids in bacteriorhodopsin photocycle behavior. |
1996 |
FEBS Lett. |
pmid:8612754
|
Tabacik C et al. |
The squalene epoxidase-cyclase activity of human term placenta. |
1973 |
FEBS Lett. |
pmid:4747843
|
Arthington-Skaggs BA et al. |
Positive and negative regulation of a sterol biosynthetic gene (ERG3) in the post-squalene portion of the yeast ergosterol pathway. |
1996 |
FEBS Lett. |
pmid:8772195
|
Garbuzov AG et al. |
Presence of squalene in human aorta. |
1966 May-Jun |
Fed Proc Transl Suppl |
pmid:5222095
|
Scallen TJ et al. |
Proceedings: Sterol carrier protein hypothesis. |
1974 |
Fed. Proc. |
pmid:4827525
|
RABINOWITZ JL et al. |
Branched chain acids in the biosynthesis of squalene and cholesterol. |
1955 |
Fed. Proc. |
pmid:13262139
|
Fukasawa LO et al. |
Adjuvant can improve protection induced by OMV vaccine against Neisseria meningitidis serogroups B/C in neonatal mice. |
2004 |
FEMS Immunol. Med. Microbiol. |
pmid:15196569
|
Kuchta T et al. |
Inhibition of ergosterol biosynthesis is not accompanied by a change in fatty acid composition in Saccharomyces cerevisiae treated with the antifungal agent 6-amino-2-n-pentylthiobenzothiazole. |
1997 |
FEMS Microbiol. Lett. |
pmid:9163904
|
Hronská L et al. |
Low concentrations of the non-ionic detergent Nonidet P-40 interfere with sterol biogenesis and viability of the yeast Saccharomyces cerevisiae. |
2004 |
FEMS Microbiol. Lett. |
pmid:15336428
|
Douka E et al. |
Structural diversity of the triterpenic hydrocarbons from the bacterium Zymomonas mobilis: the signature of defective squalene cyclization by the squalene/hopene cyclase. |
2001 |
FEMS Microbiol. Lett. |
pmid:11377875
|
Mantzouridou F and Tsimidou MZ |
Observations on squalene accumulation in Saccharomyces cerevisiae due to the manipulation of HMG2 and ERG6. |
2010 |
FEMS Yeast Res. |
pmid:20550581
|
Veen M et al. |
Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. |
2003 |
FEMS Yeast Res. |
pmid:14554200
|
Hosogaya N et al. |
The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 in Candida glabrata. |
2013 |
FEMS Yeast Res. |
pmid:23496820
|
Klesius PH et al. |
The macrophage chemotactic activity of Streptococcus agalactiae and Streptococcus iniae extracellular products (ECP). |
2007 |
Fish Shellfish Immunol. |
pmid:17212985
|
Koval'ova VA et al. |
[Effects of natural antioxidants on the content of lipids, proteins and carbohydrates in rat's gastric mucosal cells under experimental ulceration]. |
2014 |
Fiziol Zh |
pmid:25007524
|
Nováková Z et al. |
Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus. |
2010 |
Folia Microbiol. (Praha) |
pmid:20680571
|