| MeSH term | MeSH ID | Detail |
|---|---|---|
| Precancerous Conditions | D011230 | 48 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rasch MR et al. | Chains, sheets, and droplets: assemblies of hydrophobic gold nanocrystals with saturated phosphatidylcholine lipid and squalene. | 2012 | Langmuir | pmid:23033891 |
| Hoshino T et al. | Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring. | 2012 | Chemistry | pmid:22933236 |
| Wilson KR et al. | The statistical evolution of multiple generations of oxidation products in the photochemical aging of chemically reduced organic aerosol. | 2012 | Phys Chem Chem Phys | pmid:22158973 |
| Xue Z et al. | Divergent evolution of oxidosqualene cyclases in plants. | 2012 | New Phytol. | pmid:22150097 |
| Oral E et al. | A new mechanism of oxidation in ultrahigh molecular weight polyethylene caused by squalene absorption. | 2012 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:22190411 |
| Sancho A et al. | More on influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22738111 |
| Yang P et al. | Two concise enantioselective total syntheses of (-)-glabrescol implicate alternative biosynthetic pathways starting from squalene. | 2012 | Org. Lett. | pmid:22817611 |
| RamÃrez-Torres A et al. | Proteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis. | 2012 | J Proteomics | pmid:22796066 |
| Surls J et al. | Increased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory response. | 2012 | PLoS ONE | pmid:22723880 |
| Calmy A et al. | Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients. | 2012 | HIV Med. | pmid:22093373 |
| Dell'Era L et al. | Immunogenicity, safety and tolerability of MF59-adjuvanted seasonal influenza vaccine in children with juvenile idiopathic arthritis. | 2012 | Vaccine | pmid:22138210 |
| Allain V et al. | Self-assembled nucleolipids: from supramolecular structure to soft nucleic acid and drug delivery devices. | 2012 | Nucleic Acids Res. | pmid:22075995 |
| Caproni E et al. | MF59 and Pam3CSK4 boost adaptive responses to influenza subunit vaccine through an IFN type I-independent mechanism of action. | 2012 | J. Immunol. | pmid:22351935 |
| Kim SK and Karadeniz F | Biological importance and applications of squalene and squalane. | 2012 | Adv. Food Nutr. Res. | pmid:22361190 |
| Dey AK et al. | Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein. | 2012 | Vaccine | pmid:22366638 |
| Garçon N et al. | Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion. | 2012 | Expert Rev Vaccines | pmid:22380826 |
| RamÃrez-Torres A et al. | Proteomics and gene expression analyses of mitochondria from squalene-treated apoE-deficient mice identify short-chain specific acyl-CoA dehydrogenase changes associated with fatty liver amelioration. | 2012 | J Proteomics | pmid:22402057 |
| Tronchoni J et al. | Lipid composition of wine strains of Saccharomyces kudriavzevii and Saccharomyces cerevisiae grown at low temperature. | 2012 | Int. J. Food Microbiol. | pmid:22405355 |
| Liu Y et al. | [Researches on influence of squalene synthase gene polymorphism on catalytic efficiency of its encode enzyme in Glycyrrhiza uralensis]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23627178 |
| Yockel S and Schatz GC | Dynamic QM/MM: a hybrid approach to simulating gas-liquid interactions. | 2012 | Top Curr Chem | pmid:21506003 |