(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

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Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Fatigue D005221 10 associated lipids
Fibrosarcoma D005354 8 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Chronic Disease D002908 7 associated lipids
Alopecia Areata D000506 6 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Parasitemia D018512 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Peter G et al. [Gas chromatographic examinations of sebaceous gland lipids. I. Total lipid determination]. 1970 Arch Klin Exp Dermatol pmid:5477881
Rodas B and Bressani R [The oil, fatty acid and squalene content of varieties of raw and processed amaranth grain]. 2009 Arch Latinoam Nutr pmid:19480349
Schlösser E et al. Sterols in species of Pythium. 1969 Arch Mikrobiol pmid:5384630
CALTABIANO S and SPREMOLLA G [Histological and humoral aspects of experimental atherosclerosis induced by squalene in rabbits treated with triparanol]. 1963 Arch Sci Med (Torino) pmid:14017944
Henk G and Heinz T [Hydrocarbon content in the fat of meat pigs after feeding "Fermosin"]. 1993 Arch Tierernahr pmid:8572916
Dugan RE and Porter JW Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. 1972 Arch. Biochem. Biophys. pmid:4403691
Okada S et al. Molecular characterization of squalene synthase from the green microalga Botryococcus braunii, race B. 2000 Arch. Biochem. Biophys. pmid:10620354
Laden BP et al. Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase. 2000 Arch. Biochem. Biophys. pmid:10666321
Lopez D et al. Compensatory responses to inhibition of hepatic squalene synthase. 1998 Arch. Biochem. Biophys. pmid:9514656
Field RB and Holmlund CE Isolation of 2,3;22,23-dioxidosqualene and 24,25-oxidolanosterol from yeast. 1977 Arch. Biochem. Biophys. pmid:327938