| MeSH term | MeSH ID | Detail |
|---|---|---|
| Photosensitivity Disorders | D010787 | 8 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Pregnancy Complications, Infectious | D011251 | 11 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Scalp Dermatoses | D012536 | 11 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamada Y et al. | Oxidative degradation of squalene by Arthrobacter species. | 1975 | Appl Microbiol | pmid:1115507 |
| Toh TH et al. | Quantification of plasma membrane ergosterol of Saccharomyces cerevisiae by direct-injection atmospheric pressure chemical ionization/tandem mass spectrometry. | 2001 | Anal. Biochem. | pmid:11141305 |
| Greer CE et al. | The comparison of the effect of LTR72 and MF59 adjuvants on mouse humoral response to intranasal immunisation with human papillomavirus type 6b (HPV-6b) virus-like particles. | 2000 | Vaccine | pmid:11137233 |
| Tansey TR and Shechter I | Structure and regulation of mammalian squalene synthase. | 2000 | Biochim. Biophys. Acta | pmid:11111077 |
| Pedersen A et al. | An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets. | 2000 | J. Lipid Res. | pmid:11108723 |
| Jones JP et al. | Rate of sterol formation by rat brain glia and neurons in vitro and in vivo. | 1975 | J. Neurochem. | pmid:1110355 |
| de la Puerta R et al. | Effect of minor components of virgin olive oil on topical antiinflammatory assays. | 2000 Sep-Oct | Z. Naturforsch., C, J. Biosci. | pmid:11098836 |
| Relas H et al. | Postprandial retinyl palmitate and squalene metabolism is age dependent. | 2000 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:11078083 |
| Finotti E et al. | Synergistic effects of alpha-tocopherol, beta-sitosterol and squalene on antioxidant activity assayed by crocin bleaching method. | 2000 | Nahrung | pmid:11075383 |
| Smith TJ | Squalene: potential chemopreventive agent. | 2000 | Expert Opin Investig Drugs | pmid:11060781 |
| Vendt VP | [Studies in the field of chemistry, biochemistry and photobiochemistry of sterols]. | 1975 Sep-Oct | Ukr Biokhim Zh | pmid:1105921 |
| Dang T and Prestwich GD | Site-directed mutagenesis of squalene-hopene cyclase: altered substrate specificity and product distribution. | 2000 | Chem. Biol. | pmid:11048954 |
| Matyas GR et al. | Induction and detection of antibodies to squalene. | 2000 | J. Immunol. Methods | pmid:11042279 |
| Matthan NR et al. | Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women. | 2000 | Lipids | pmid:11026626 |
| Bartfai E et al. | [Studies on the genotoxic effects of crude liver oils from 3 species of Mediterranean sharks by means of in vitro micronucleus test using human lymphocytes]. | 2000 Sep-Oct | Ann. Biol. Clin. (Paris) | pmid:11022102 |
| Berekaa MM and Steinbüchel A | Microbial degradation of the multiply branched alkane 2,6,10,15,19, 23-hexamethyltetracosane (Squalane) by Mycobacterium fortuitum and Mycobacterium ratisbonense. | 2000 | Appl. Environ. Microbiol. | pmid:11010899 |
| Moreau JP et al. | Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. | 1975 | Eur. J. Biochem. | pmid:1100393 |
| Relas H et al. | Dietary squalene increases cholesterol synthesis measured with serum non-cholesterol sterols after a single oral dose in humans. | 2000 | Atherosclerosis | pmid:10998465 |
| Giacomoni PU et al. | Aging of human skin: review of a mechanistic model and first experimental data. | 2000 | IUBMB Life | pmid:10995026 |
| Barton DH et al. | Investigations on the biosynthesis of steroids and terpenoids. Part XII. Biosynthesis of 3beta-hydroxy-triterpenoids and -steroids from (3S)-2,3-epoxy-2,3-dihydrosqualene. | 1975 | J. Chem. Soc. Perkin Trans. I | pmid:1099108 |