(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Viremia D014766 4 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Xanthomatosis D014973 17 associated lipids
Weight Gain D015430 101 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Coronavirus Infections D018352 4 associated lipids
Parasitemia D018512 5 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Ryder NS Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent. 1985 Antimicrob. Agents Chemother. pmid:4039119
Buckner FS et al. Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors. 2001 Antimicrob. Agents Chemother. pmid:11257036
Ryder NS et al. Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. 1984 Antimicrob. Agents Chemother. pmid:6375557
Siegrist CA et al. Responses of solid organ transplant recipients to the AS03-adjuvanted pandemic influenza vaccine. 2012 Antivir. Ther. (Lond.) pmid:22544169
Hunter MI et al. The effect of temperature on the growth and lipid composition of the extremely halophilic coccus, Sarcina marina. 1981 Antonie Van Leeuwenhoek pmid:7247392
Yamada Y et al. Oxidative degradation of squalene by Arthrobacter species. 1975 Appl Microbiol pmid:1115507
Williams DK et al. Analysis of latent fingerprint deposits by infrared microspectroscopy. 2004 Appl Spectrosc pmid:15035712
Rajaram K et al. Comparative bioactive studies between wild plant and callus culture of Tephrosia tinctoria pers. 2013 Appl. Biochem. Biotechnol. pmid:24026411
Yamada Y et al. Oxidation of linear terpenes and squalene variants by Arthrobacter sp. 1977 Appl. Environ. Microbiol. pmid:869527
Donald KA et al. Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae. 1997 Appl. Environ. Microbiol. pmid:9292983