| MeSH term | MeSH ID | Detail |
|---|---|---|
| Viremia | D014766 | 4 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Simian Acquired Immunodeficiency Syndrome | D016097 | 4 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Persian Gulf Syndrome | D018923 | 1 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| TCHEN TT and BLOCH K | On the conversion of squalene to lanosterol in vitro. | 1957 | J. Biol. Chem. | pmid:13438881 |
| TCHEN TT and BLOCH K | On the mechanism of enzymatic cyclization of squalene. | 1957 | J. Biol. Chem. | pmid:13438882 |
| SOBEL H et al. | Determinations of squalene in sebum from the forehead of patients with skin cancer. | 1957 | J. Invest. Dermatol. | pmid:13491890 |
| DITURI F et al. | Precursors of squalene and cholesterol. | 1957 | J. Biol. Chem. | pmid:13502345 |
| VILLALBA GOMEZ GM | [Squalene index]. | 1956 May-Aug | Rev Sanid Asist Soc | pmid:13379961 |
| SQUALENE and cholesterol synthesis in the human skin. | 1956 | Nutr. Rev. | pmid:13309889 | |
| DITURI F et al. | Terpenoid intermediates in the biosynthesis of cholesterol. | 1956 | J. Biol. Chem. | pmid:13345809 |
| NICOLAIDES N and ROTHMAN S | The site of sterol and squalene synthesis in the human skin. | 1955 | J. Invest. Dermatol. | pmid:14354270 |
| BOUGHTON B et al. | Some observations of the nature, origin and possible function of the squalene and other hydrocarbons of human sebum. | 1955 | J. Invest. Dermatol. | pmid:14354278 |
| MACKENNA RM et al. | Squalene and other hydrocarbons in human sebum. | 1955 | J. Physiol. (Lond.) | pmid:14354699 |
| DICKHART W | The squalene contents of various oils. | 1955 | Am J Pharm Sci Support Public Health | pmid:13275573 |
| RABINOWITZ JL et al. | Branched chain acids in the biosynthesis of squalene and cholesterol. | 1955 | Fed. Proc. | pmid:13262139 |
| CORNFORTH JW and POPJAK G | Studies on the biosynthesis of cholesterol. 3. Distribution of 14C in squalene biosynthesized from [Me-14C]acetate. | 1954 | Biochem. J. | pmid:13208629 |
| SQUALENE, a precursor of cholesterol. | 1954 | Nutr. Rev. | pmid:13166142 | |
| EIDINOFF ML et al. | The biosynthesis of squalene from acetate in man. | 1954 | J. Clin. Invest. | pmid:13143078 |
| POPJAK G | Biosynthesis of squalene and cholesterol in vitro from acetate-1-C14. | 1954 | Arch. Biochem. Biophys. | pmid:13125576 |
| SCHWENK E et al. | Studies on the biosynthesis of cholesterol. VI. Companions of cholesterol-C14 in liver perfusions, including squalene-C14 as possible precursors in its biosynthesis. | 1954 | Arch. Biochem. Biophys. | pmid:13139684 |
| WHEATLEY VR | Studies of sebum. IV. The estimation of squalene in sebum and sebum-like materials. | 1953 | Biochem. J. | pmid:13115346 |
| LANGDON RG and BLOCH K | The biosynthesis of squalene. | 1953 | J. Biol. Chem. | pmid:13034767 |
| LANGDON RG and BLOCH K | The utilization of squalene in the biosynthesis of cholesterol. | 1953 | J. Biol. Chem. | pmid:13034768 |