(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Cholelithiasis D002769 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Celiac Disease D002446 16 associated lipids
Brain Diseases D001927 27 associated lipids
Body Weight D001835 333 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Arthritis D001168 41 associated lipids
Arteriosclerosis D001161 86 associated lipids
Olfaction Disorders D000857 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
GRIESEMER RD and THOMAS RW LIPOGENESIS IN HUMAN SKIN. III. VARIATION WITH BODY SITE. 1963 J. Invest. Dermatol. pmid:14066602
PROSTENIK M and MUNK-WEINERT M The isolation of squalene from human brain. 1963 Biochim. Biophys. Acta pmid:13986372
BURGESS TL and WILSON JD Studies on hormonal regulation of squalene synthesis in preputial gland and skin of the rat. 1963 Proc. Soc. Exp. Biol. Med. pmid:14016990
CALTABIANO S and SPREMOLLA G [Histological and humoral aspects of experimental atherosclerosis induced by squalene in rabbits treated with triparanol]. 1963 Arch Sci Med (Torino) pmid:14017944
CARAVACA J et al. Inhibition of squalene and cholesterol biosynthesis by hepatocatalase (Caperase). 1963 Biochem. Biophys. Res. Commun. pmid:14018515
CORNFORTH JW et al. Stereospecific insertion of hydrogen atom into squalene from reduced nicotinamide-adenine dinucleotides. 1963 Biochem. Biophys. Res. Commun. pmid:14023096
Paroli E [Effect of beta-carotene and of squalene on analgesia and respiratory depression caused by morphine]. 1964 Boll. Soc. Ital. Biol. Sper. pmid:5877121
GOODMAN DS SQUALENE IN HUMAN AND RAT BLOOD PLASMA. 1964 J. Clin. Invest. pmid:14192529
SALOKANGAS RA et al. TERPENE METABOLISM IN THE RAT TESTIS. I. THE CONVERSION OF ISOPENTENYL PYROPHOSPHATE TO SQUALENE AND STEROLS. 1964 Biochemistry pmid:14211625
MCCARTHY MJ et al. COMPOSITION OF MOLECULAR DISTILLATES OF BUTTER OIL: ISOLATION AND IDENTIFICATION OF COMPONENTS OTHER THAN GLYCERIDES. 1964 J. Lipid Res. pmid:14221107