| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
| Okada S et al. | Molecular characterization of squalene synthase from the green microalga Botryococcus braunii, race B. | 2000 | Arch. Biochem. Biophys. | pmid:10620354 |
| Laden BP et al. | Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase. | 2000 | Arch. Biochem. Biophys. | pmid:10666321 |
| Trocha PJ and Sprinson DB | Location and regulation of early enzymes of sterol biosynthesis in yeast. | 1976 | Arch. Biochem. Biophys. | pmid:7207 |
| Lopez D et al. | Compensatory responses to inhibition of hepatic squalene synthase. | 1998 | Arch. Biochem. Biophys. | pmid:9514656 |
| Field RB and Holmlund CE | Isolation of 2,3;22,23-dioxidosqualene and 24,25-oxidolanosterol from yeast. | 1977 | Arch. Biochem. Biophys. | pmid:327938 |
| Fujita H et al. | Chlorpromazine-sensitized photooxidation of squalene. | 1986 | Arch. Dermatol. Res. | pmid:3729541 |
| Fujie T et al. | Culture of cells derived from the human sebaceous gland under serum-free conditions without a biological feeder layer or specific matrices. | 1996 | Arch. Dermatol. Res. | pmid:8931874 |
| Yamamoto A et al. | Impaired water barrier function in acne vulgaris. | 1995 | Arch. Dermatol. Res. | pmid:7763094 |
| Saxena SC and Zandee DI | Biosynthesis of fatty acids and cholesterol in a fresh-water carp, "Scardinius erythrophthalmus" from sodium acetate-1-14C. | 1969 | Arch. Int. Physiol. Biochim. | pmid:4188405 |