MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rao KS and Olson RE | The effect of exogenous cholesterol on the synthesis in vivo of cholesterol, ubiquinone, and squalene in rat liver. | 1967 | Biochem. Biophys. Res. Commun. | pmid:6030977 |
Johnson WS | Nonenzymic biogenetic-like olefinic cyclizations. | 1967 | Trans N Y Acad Sci | pmid:5237390 |
Benveniste P et al. | [Biosynthesis of squalene with the help of microsomes originating from the tissue of tobacco cultivated in vitro]. | 1967 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:4967365 |
Willett JD et al. | Squalene-2,3oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol. | 1967 | J. Biol. Chem. | pmid:6061706 |
van Tamelen EE et al. | Enzymic cyclization of trans,trans,trans-18,19-dihydrosqualene 2,3-oxide. | 1967 | J. Am. Chem. Soc. | pmid:6064361 |
Kishi M et al. | Acid-catalyzed cyclization of squalene oxide. | 1967 | Chem. Pharm. Bull. | pmid:5583148 |
Katsuki H and Bloch K | Studies on the biosynthesis of ergosterol in yeast. Formation of methylated intermediates. | 1967 | J. Biol. Chem. | pmid:6016607 |
Kellum RE | Human sebaceous gland lipids. Analysis by thin-layer chromatography. | 1967 | Arch Dermatol | pmid:6019001 |
Matschiner JT et al. | Effect of indigestible oils on vitamin K deficiency in the rat. | 1967 | J. Nutr. | pmid:6021812 |
Matschiner JT et al. | Mechanism of the effect of retinoic acid and squalene on vitamin K deficiency in the rat. | 1967 | J. Nutr. | pmid:6021953 |