MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Luan Z et al. | Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12663370 |
Schulz-Gasch T and Stahl M | Mechanistic insights into oxidosqualene cyclizations through homology modeling. | 2003 | J Comput Chem | pmid:12666166 |
Banzhoff A et al. | A new MF59-adjuvanted influenza vaccine enhances the immune response in the elderly with chronic diseases: results from an immunogenicity meta-analysis. | 2003 May-Jun | Gerontology | pmid:12679609 |
Hendler RW et al. | Purple membrane lipid control of bacteriorhodopsin conformational flexibility and photocycle activity. | 2003 | Eur. J. Biochem. | pmid:12709050 |
Ahrens EH | Sterol balance in hyperlipidemic patients after dietary exchange of carbohydrate for fat. | 1976 | J. Lipid Res. | pmid:1270936 |
Lu HT et al. | Preparative separation and purification of squalene from the microalga Thraustochytrium ATCC 26185 by high-speed counter-current chromatography. | 2003 | J Chromatogr A | pmid:12779217 |
Chiba K et al. | Characteristics of skin wrinkling and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin. | 2003 Jul-Aug | Skin Pharmacol. Appl. Skin Physiol. | pmid:12784064 |
Rocco F et al. | Conjugated methyl sulfide and phenyl sulfide derivatives of oxidosqualene as inhibitors of oxidosqualene and squalene-hopene cyclases. | 2003 | Lipids | pmid:12784859 |
Ekanayake Mudiyanselage S et al. | Ultraviolet a induces generation of squalene monohydroperoxide isomers in human sebum and skin surface lipids in vitro and in vivo. | 2003 | J. Invest. Dermatol. | pmid:12787115 |
Madani KA | Effects of trace components of dietary fat on cholesterol metabolism: phytosterols, oxysterols, and squalene. | 2003 | Nutr. Rev. | pmid:12795450 |