MeSH term | MeSH ID | Detail |
---|---|---|
Ossification, Heterotopic | D009999 | 2 associated lipids |
Pneumonia, Lipid | D011017 | 2 associated lipids |
Persian Gulf Syndrome | D018923 | 1 associated lipids |
Hemorrhagic Septicemia, Viral | D031941 | 1 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Emmons GT et al. | Effects of 20,25-diazacholesterol on cholesterol synthesis in cultured chick muscle cells: a radiogas chromatographic and mass spectrometric study of the post-squalene sector. | 1982 | Biomed. Mass Spectrom. | pmid:7126761 |
Morozova RP et al. | [Separation of lipid extract from animal blood and tissues and isolation of squalene and sterols from it]. | 1982 Jul-Aug | Ukr. Biokhim. Zh. | pmid:7135500 |
Maugh TH | Completing the puzzle of steroid synthesis, a mystery in the biological synthesis of steroids is solved, providing a new approach to chemical synthesis of the compounds. | 1982 | Science | pmid:7146911 |
Olugbade TA et al. | Chemical constituents of Cnestis ferruginea DC. I. Petroleum ether fraction. | 1982 | J Ethnopharmacol | pmid:7154704 |
Morin RJ and Srikantaiah MV | Inhibition of rat liver sterol formation by isoprenoid and conjugated ene compounds. | 1982 | Pharmacol Res Commun | pmid:7156175 |
Bell FP and Hubert EV | Stimulation of hepatic squalene and triglyceride synthesis by dimethylsulfoxide, in vitro. | 1982 | Lipids | pmid:7162368 |
PokrovskiÄ AA et al. | [Method of isolating, identifying and quantitatively determining alkanes, cycloalkanes, monocyclic arenes and squalene in animal organs and tissues]. | 1978 Sep-Oct | Vopr Pitan | pmid:716335 |
Bird S and Gower DB | Axillary 5 alpha-androst-16-en-3-one, cholesterol and squalene in men; preliminary evidence for 5 alpha-androst-16-en-3-one being a product of bacterial action. | 1982 | J. Steroid Biochem. | pmid:7176644 |
Albers-Jackson B et al. | Incorporation of 14C acetate into the sterols of rabbit lens in organ culture. | 1982-1983 | Curr. Eye Res. | pmid:7184713 |
Miettinen TA | Diurnal variation of cholesterol precursors squalene and methyl sterols in human plasma lipoproteins. | 1982 | J. Lipid Res. | pmid:7200504 |
Trocha PJ and Sprinson DB | Location and regulation of early enzymes of sterol biosynthesis in yeast. | 1976 | Arch. Biochem. Biophys. | pmid:7207 |
Yarkoni E et al. | Immunotherapy of experimental cancer with a mixture of synthetic muramyl dipeptide and trehalose dimycolate. | 1981 | Infect. Immun. | pmid:7216489 |
Lindholm JS and Downing DT | Occurrence of squalene in skin surface lipids of the otter, the beaver and the kinkajou. | 1980 | Lipids | pmid:7219074 |
Brassell SC et al. | Specific acyclic isoprenoids as biological markers of methanogenic bacteria in marine sediments. | 1981 | Nature | pmid:7219553 |
Sirtori CR et al. | Reduced triglyceridemia and increased high density lipoprotein cholesterol levels after treatment with acipimox, a new inhibitor of lipolysis. | 1981 Feb-Mar | Atherosclerosis | pmid:7225165 |
Pimm MV et al. | Suppression of an ascitic rat hepatoma with cord factor and Nocardia cell wall skeleton in squalene emulsions. | 1980 | Eur J Cancer | pmid:7227439 |
Anisimov MM et al. | [Effect of triterpene glycosides on the biosynthesis of sterols and fatty acids by the yeast Saccharomyces carlsbergensis]. | 1978 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:724665 |
Hunter MI et al. | The effect of temperature on the growth and lipid composition of the extremely halophilic coccus, Sarcina marina. | 1981 | Antonie Van Leeuwenhoek | pmid:7247392 |
Ito M et al. | Killing of tumor cells in vitro by macrophages from mice given injections of squalene-treated cell wall skeleton of Nocardia rubra. | 1981 | Cancer Res. | pmid:7248952 |
Kojima Y et al. | Protein-facilitated intermembrane transfer of squalene. Demonstration by density gradient centrifugation. | 1981 | J. Biol. Chem. | pmid:7251595 |
Wysocki SJ et al. | Lipids in forehead vernix from newborn infants. | 1981 | Biol. Neonate | pmid:7260215 |
Carelli C et al. | Persistent enhancement of cell-mediated and antibody immune responses after administration of muramyl dipeptide derivatives with antigen in metabolizable oil. | 1981 | Infect. Immun. | pmid:7263069 |
Tornabene TG | Formation of hydrocarbons by bacteria and algae. | 1981 | Basic Life Sci. | pmid:7271715 |
Ivashkevich SP et al. | [Effects of sterols having different chemical structure and squalene on osmotic resistance of erythrocytes]. | 1981 | Biokhimiia | pmid:7272362 |
McGinley KJ et al. | Regional variations in density of cutaneous propionibacteria: correlation of Propionibacterium acnes populations with sebaceous secretion. | 1980 | J. Clin. Microbiol. | pmid:7276142 |
Downing DT et al. | Estimation of sebum production rates in man by measurement of the squalene content of skin biopsies. | 1981 | J. Invest. Dermatol. | pmid:7276619 |
Mironova VN and Chaialo PP | [Cholesterol biosynthesis in the blood of rabbits with experimental atherosclerosis]. | 1978 | Biull Eksp Biol Med | pmid:728610 |
Miettinen TA and Tilvis R | Comparison of different components in the fractional conversion of mevalonate to cholesterol with cholesterol synthesis and serum methyl sterols. | 1981 | Scand. J. Clin. Lab. Invest. | pmid:7313530 |
Miettinen TA and Tilvis RS | Cholesterol synthesis and storage in adipose tissue. | 1981 | Int J Obes | pmid:7319685 |
Strandberg TE et al. | Squalene and sterol synthesis in isolated small-intestinal cells of the rat. | 1981 | Scand. J. Gastroenterol. | pmid:7323711 |
Bell FP | Effect of di-2-ethylhexyl phthalate in the female rat: inhibition of hepatic and adrenal sterologenesis in vitro. | 1980 | Bull Environ Contam Toxicol | pmid:7357111 |
Falcone DJ et al. | Enhancement of cholesterol and cholesteryl ester accumulation in re-endothelialized aorta. | 1980 | Am. J. Pathol. | pmid:7361865 |
Caras IW et al. | Interactions of supernatant protein factor with components of the microsomal squalene epoxidase system. Binding of supernatant protein factor to anionic phospholipids. | 1980 | J. Biol. Chem. | pmid:7364757 |
Shao MJ and Lei KY | Conversion of [2-14C] mevalonate into cholesterol, lanosterol and squalene in copper-deficient rats. | 1980 | J. Nutr. | pmid:7373433 |
Shechter I et al. | A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes. | 1980 | J. Lipid Res. | pmid:7381322 |
Friedlander EJ et al. | Supernatant protein factor facilitates intermembrane transfer of squalene. | 1980 | J. Biol. Chem. | pmid:7410347 |
Matsumoto G and Hanya T | Presence of squalane in urban aquatic environments. | 1980 | J. Chromatogr. | pmid:7410506 |
Srikantaiah MV et al. | Inhibition of rat hepatic sterol formation from squalene by plasma lipoproteins. | 1980 | Lipids | pmid:7432102 |
Nelson JA et al. | Biosynthesis of 24,25-epoxycholesterol from squalene 2,3;22,23-dioxide. | 1981 | J. Biol. Chem. | pmid:7451488 |
Rohmer M et al. | Non-specific biosynthesis of hopane triterpenes by a cell-free system from Acetobacter pasteurianum. | 1980 | Eur. J. Biochem. | pmid:7460938 |
Morin RJ and Srikantaiah MV | In vitro conversion of squalene from squalene-phospholipid liposomes into sterols by rat liver microsomes and cytosol. | 1980 | J. Lipid Res. | pmid:7462811 |
Soloway AH and LeQuesne PW | Potential endogenous mutagens/carcinogens. | 1980 | J. Theor. Biol. | pmid:7464159 |
Robuccio JA et al. | Comparison of the effects of five adjuvants on the antibody response to influenza virus antigen in guinea pigs. | 1995 | Lab. Anim. Sci. | pmid:7474883 |
Lewis D et al. | Enzyme inhibition during the conversion of squalene to cholesterol. | 1995 | Steroids | pmid:7482633 |
PerederiÄ OF and Morozova RP | [Squalene and sterols of rat stomach tissue and the effect of acetylsalicylic acid on their content]. | 1978 Nov-Dec | Ukr. Biokhim. Zh. | pmid:749299 |
Yoshino S and Yoshino J | Recruitment of pathogenic T cells to synovial tissues of rats injected intraarticularly with nonspecific agents. | 1994 | Cell. Immunol. | pmid:7522973 |
Ott G et al. | MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. | 1995 | Pharm Biotechnol | pmid:7551221 |
Viola F et al. | Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. | 1995 | Biochem. Pharmacol. | pmid:7575639 |
Nagumo A et al. | Purification and characterization of recombinant squalene epoxidase. | 1995 | J. Lipid Res. | pmid:7595073 |
Pittler SJ et al. | In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure. | 1995 | J. Cell Biol. | pmid:7615641 |