(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Steatorrhea D045602 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Van Leusden H and Villee CA The de novo synthesis of sterols and steroids from acetate by preparations of human term placenta. 1965 Steroids pmid:5857495
SHORB MS et al. EFFECT OF TRIPARANOL ON SYNTHESIS OF SQUALENE AND TETRAHYMANOL BY TETRAHYMENA PYRIFORMIS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14277681
NUSBAUM-CASSUTO E and VILLOUTREIX J [DEMONSTRATION OF LYCOPERSENE IN HIGHER PLANTS]. 1965 C. R. Hebd. Seances Acad. Sci. pmid:14287016
NICHOLAS HJ and BOMBAUGH KJ CONSTITUENTS OF THE HYDROCARBON FRACTION OF BEEF BRAINS. 1965 Biochim. Biophys. Acta pmid:14320231
CAPSTACKE JR et al. SQUALENE IN PISUM SATIVUM. ITS CYCLIZATION TO BETA-AMYRIN AND LABELING PATTERN. 1965 J. Biol. Chem. pmid:14321361
HELLIG HR and SAVARD K BIOSYNTHESIS OF PROGESTERONE, STEROLS, AND SQUALENE FROM ACETATE-1-14-C AND MEVALONATE-2-14-C BY THE BOVINE CORPUS LUTEUM IN VITRO. 1965 J. Biol. Chem. pmid:14299614
Dalidowicz JE and McDonald HJ Site of the in vitro inhibition of cholesterol biosynthesis by tolbutamide and phenethylbiguanide. 1965 Biochemistry pmid:4284598
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Cornforth JW et al. Studies on the biosynthesis of cholesterol. XVII. The asymmetric synthesis of a symmetrical molecule. 1966 Proc. R. Soc. Lond., B, Biol. Sci. pmid:4379289
Cornforth JW et al. Studies on the biosynthesis of cholesterol XIX. Steric course of hydrogen eliminations and of C-C bond formations in squalene biosynthesis. 1966 Proc. R. Soc. Lond., B, Biol. Sci. pmid:4379291
Blondin GA et al. The biosynthesis of squalene and sterols in fish. 1966 Comp. Biochem. Physiol. pmid:4380202
Rilling HC A new intermediate in the biosynthesis of squalene. 1966 J. Biol. Chem. pmid:4287912
Gaylor JL et al. Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis. 1966 J. Lipid Res. pmid:4290536
Lynen F [The biochemical basis of the biosynthesis of cholesterol and fatty acids]. 1966 Wien. Klin. Wochenschr. pmid:4296920
Cory EJ et al. 2,3-oxidosqualene, an intermediate in the biological synthesis of sterols from squalene. 1966 J. Am. Chem. Soc. pmid:5918046
Corey EJ and Russey WE Metabolic fate of 10,11-dihydrosqualene in sterol-producing rat liver homogenate. 1966 J. Am. Chem. Soc. pmid:5918047
Van Tamelen EE et al. Enzymic conversion of squalene 2,3-oxide to lanosterol and cholesterol. 1966 J. Am. Chem. Soc. pmid:5918048
Cmelik SH and Webster GD Squalene in vernix caseosa from African neonates. 1966 Cent Afr J Med pmid:5919884
Hsia SL et al. Lipid metabolism in human skin. I. Lipogenesis from acetate-1-14C. 1966 J. Invest. Dermatol. pmid:5924299
Butterworth PH et al. In vivo incorporation of [2-14-C]-mevalonate into dolichol of rabbit and pig liver. 1966 Arch. Biochem. Biophys. pmid:5944963