MeSH term | MeSH ID | Detail |
---|---|---|
Alzheimer Disease | D000544 | 76 associated lipids |
Alopecia Areata | D000506 | 6 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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SQUALENE and cholesterol synthesis in the human skin. | 1956 | Nutr. Rev. | pmid:13309889 | |
VILLALBA GOMEZ GM | [Squalene index]. | 1956 May-Aug | Rev Sanid Asist Soc | pmid:13379961 |
BOUGHTON B et al. | Studies of sebum. VIII. Observations on the squalene and cholesterol content and the possible functions of squalene in human sebum. | 1957 | Biochem. J. | pmid:13426103 |
HELLER JH et al. | Squalene content of various shark livers. | 1957 | Nature | pmid:13430738 |
TCHEN TT and BLOCH K | On the conversion of squalene to lanosterol in vitro. | 1957 | J. Biol. Chem. | pmid:13438881 |
TCHEN TT and BLOCH K | On the mechanism of enzymatic cyclization of squalene. | 1957 | J. Biol. Chem. | pmid:13438882 |
SOBEL H et al. | Determinations of squalene in sebum from the forehead of patients with skin cancer. | 1957 | J. Invest. Dermatol. | pmid:13491890 |
DITURI F et al. | Precursors of squalene and cholesterol. | 1957 | J. Biol. Chem. | pmid:13502345 |
CORNFORTH JW et al. | Studies on the biosynthesis of cholesterol. 5. Biosynthesis of squalene from DL-3-hydroxy-3-methyl [2-14C] pentano-5-lactone. | 1958 | Biochem. J. | pmid:13535596 |
WOLFF RE and GODEFROY N | [Transformation of synthetic squalene (11, 1414C) to cholesterol in rats]. | 1958 | C. R. Hebd. Seances Acad. Sci. | pmid:13537384 |
WOLFF RE and PICHAT L | [Synthesis of 11,14-C14-squalene]. | 1958 | C. R. Hebd. Seances Acad. Sci. | pmid:13537435 |
EIDINOFF ML et al. | Cholesterol biosynthesis: studies related to the metabolic role of squalene. | 1958 | J. Clin. Invest. | pmid:13539207 |
POPJAK G et al. | Studies on the biosynthesis of cholesterol. 6. Coenzyme requirements of liver enzymes for synthesis of squalene and of sterol from DL-3-hydroxy-3-methyl-[2-14C] pentano-5-lactone. | 1958 | Biochem. J. | pmid:13546172 |
LOUD AV and BUCHER NL | The turnover of squalene in relation to the biosynthesis of cholesterol. | 1958 | J. Biol. Chem. | pmid:13563436 |
WITTING LA and PORTER JW | Intermediates in the conversion of mevalonic acid to squalene by a rat liver enzyme system. | 1959 | J. Biol. Chem. | pmid:13845505 |
KROENING F | [On the induction of leukemia in C57B1 mice following painting of the dorsal part of the skin with short-chain fatty acids, fatty acid esters and with squalene]. | 1959 | Acta Unio Int Contra Cancrum | pmid:13848508 |
NICHOLAS HJ and THOMAS BE | Intracerebral incorporation of [2-14C]mevalonic acid into adult rat brain squalene and cholesterol. | 1959 | Biochim. Biophys. Acta | pmid:13854106 |
MARKLEY K and GURIN S | Decarboxylation of mevalonic acid and conversion to squalene; enzyme fractionation and cofactors. | 1959 | Biochim. Biophys. Acta | pmid:13628647 |
RILLING HC and BLOCH K | On the mechanism of squaiene biogenesis from mevalonic acid. | 1959 | J. Biol. Chem. | pmid:13654391 |
WOOTTON JM and WRIGHT LD | Biosynthesis of squalene by the annelid Lumbricus terrestris. | 1960 | Nature | pmid:13786660 |