MeSH term | MeSH ID | Detail |
---|---|---|
Alzheimer Disease | D000544 | 76 associated lipids |
Alopecia Areata | D000506 | 6 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Acne Vulgaris | D000152 | 35 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fox CB et al. | Immunomodulatory and physical effects of phospholipid composition in vaccine adjuvant emulsions. | 2012 | AAPS PharmSciTech | pmid:22415641 |
Arias JL et al. | Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics. | 2011 | ACS Nano | pmid:21275408 |
Maksimenko A et al. | Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacy. | 2014 | ACS Nano | pmid:24555414 |
Sémiramoth N et al. | Self-assembled squalenoylated penicillin bioconjugates: an original approach for the treatment of intracellular infections. | 2012 | ACS Nano | pmid:22482704 |
Jawaid AM et al. | Shape-controlled colloidal synthesis of rock-salt lead selenide nanocrystals. | 2011 | ACS Nano | pmid:21770427 |
Schubert K and Schumann W | [On the biosynthesis of sterines]. | 1967 | Acta Biol. Med. Ger. | pmid:5593407 |
Mullakhanbhai MF and Francis GW | Bacterial lipids. 1. Lipid constituents of a moderately halophilic bacterium. | 1972 | Acta Chem Scand | pmid:5049648 |
Liu CI et al. | Structural insights into the catalytic mechanism of human squalene synthase. | 2014 | Acta Crystallogr. D Biol. Crystallogr. | pmid:24531458 |
Cunliffe WJ et al. | An explanation fro chloracne -- an industrial hazard. | 1975 | Acta Derm. Venereol. | pmid:50695 |
Cotterill JA et al. | Variation in skin surface lipid composition and sebum excretion rate with time. | 1973 | Acta Derm. Venereol. | pmid:4127454 |
van Leusden HA et al. | Squalene and lanosterol synthesis in the foeto-placental unit at midgestation. | 1971 | Acta Endocrinol. | pmid:5108099 |
Zadák Z et al. | Polyunsaturated fatty acids, phytosterols and cholesterol metabolism in the Mediterranean diet. | 2006 | Acta Medica (Hradec Kralove) | pmid:16696439 |
Arffmann E and Glavind J | Studies by the newt test on carcinogenic properties of rats. | 1967 | Acta Pathol Microbiol Scand | pmid:6050372 |
Ismail AA et al. | Interrelation between thyroid hormones and essential fatty acids. | 1966 | Acta Physiol Acad Sci Hung | pmid:5953398 |
Edgren B and Hellström K | Lipid biosynthesis from DL (2- 14 C) mevalonic acid in intact mice and rabbits. | 1972 | Acta Physiol. Scand. | pmid:4640173 |
KROENING F | [On the induction of leukemia in C57B1 mice following painting of the dorsal part of the skin with short-chain fatty acids, fatty acid esters and with squalene]. | 1959 | Acta Unio Int Contra Cancrum | pmid:13848508 |
Caron J et al. | Improving the antitumor activity of squalenoyl-paclitaxel conjugate nanoassemblies by manipulating the linker between paclitaxel and squalene. | 2013 | Adv Healthc Mater | pmid:23213041 |
Yasuda Y et al. | Comparison of half and full doses of an MF59-adjuvanted cell culture-derived A/H1N1v vaccine in Japanese children. | 2010 | Adv Ther | pmid:20586002 |
Haralampidis K et al. | Biosynthesis of triterpenoid saponins in plants. | 2002 | Adv. Biochem. Eng. Biotechnol. | pmid:11783842 |
Reddy LH and Couvreur P | Squalene: A natural triterpene for use in disease management and therapy. | 2009 | Adv. Drug Deliv. Rev. | pmid:19804806 |