MeSH term | MeSH ID | Detail |
---|---|---|
Pneumonia, Lipid | D011017 | 2 associated lipids |
Persian Gulf Syndrome | D018923 | 1 associated lipids |
Steatorrhea | D045602 | 2 associated lipids |
Hemorrhagic Septicemia, Viral | D031941 | 1 associated lipids |
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ferezou JP et al. | [The absence of sterol and squalene biosynthesis a coelenterata (anthozoa), the sea anemone Calliactis parasitica]. | 1972 | Experientia | pmid:4402545 |
Dugan RE and Porter JW | Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. | 1972 | Arch. Biochem. Biophys. | pmid:4403691 |
Walton MJ and Pennock JF | Some studies on the biosynthesis of ubiguinone, isoprenoid alcohols, squalene and sterols by marine invertebrates. | 1972 | Biochem. J. | pmid:4403925 |
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Green TR and Baisted DJ | Development of the activities of enzymes of the isoprenoid pathway during early stages of pea-seed germination. | 1972 | Biochem. J. | pmid:4348263 |
Nitchuk WM and Ainsworth L | The de novo synthesis of sterols and cholesterol from acetate-1- 14 C by sheep and pig placental and fetal liver slices in vitro. | 1972 | Steroids | pmid:5028884 |
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Coates RM and Robinson WH | Solvolysis of trans-2,2-dimethyl-3-(2'-methylpropenyl)cyclobutyl tosylate. Model reactions relevant to squalene biosynthesis. | 1972 | J. Am. Chem. Soc. | pmid:5053868 |
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Slakey LL et al. | The effect of starvation and re-feeding on the rates of synthesis and degradation of enzyms effecting intermediate reactions in the synthesis of cholesterol and fatty acids in rat liver. | 1972 | Biochem. J. | pmid:5085557 |
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Bazzano G and Bazzano GS | Hypocholesterolemic effect of -ketoglutarate in the Mongolian gerbil. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5033114 |
Tai HH and Bloch K | Squalene epoxidase of rat liver. | 1972 | J. Biol. Chem. | pmid:5033388 |
Kramer JK et al. | Structure ditermination of the squalene, dihydrosqualene and tetrahydrosqualene in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5037322 |
Kushwaha SC et al. | Isolation and identification of dehydrosqualene and C 40 -carotenoid pigments in Halobacterium cutirubrum. | 1972 | Biochim. Biophys. Acta | pmid:5038263 |
Avigan J et al. | In vitro biosynthesis of lipids, proteins and deoxyribonucleic acid in aortic tissue and in culture aortic cells. | 1972 | Biochim. Biophys. Acta | pmid:5041430 |
Nicolosi RJ et al. | Lipid accumulation in muscular foci in White Carneau and Show Racer pigeon aortas. | 1972 | Exp. Mol. Pathol. | pmid:5043333 |
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Slakey LL et al. | The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. | 1972 | J. Biol. Chem. | pmid:4337504 |
Polito A et al. | Artificial substrates in squalene and sterol biosynthesis. | 1972 | J. Biol. Chem. | pmid:4337856 |
Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
Qureshi AA et al. | Squalene synthetase. I. Dissociation and reassociation of enzyme complex. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4341049 |
Malhotra HC and Nes WR | The conversion of mevalonate to 24-methylenecycloartanol by a cell-free enzyme preparation from nonphotosynthetic tissue. | 1972 | J. Biol. Chem. | pmid:4651646 |
Heintz R et al. | Plant sterol metabolism. Demonstration and identification of a biosynthetic intermediate between farnesyl PP and squalene in a higher plant. | 1972 | Biochem. Biophys. Res. Commun. | pmid:4344813 |
Atkin SD et al. | The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. | 1972 | Biochem. J. | pmid:4655417 |
Asakawa A et al. | The effect of nicotinamide on the cholesterol biosynthesis by cell-free rat brain extract. | 1972 | J Nihon Univ Sch Dent | pmid:4269195 |
Cotterill JA et al. | Variations in skin surface lipid composition and sebum excretion rate with different sampling techniques. II. | 1972 | Br. J. Dermatol. | pmid:4260102 |
Gloor M et al. | [Skin surface lipids: qualitative and quantitative determination in patients with acne vulgaris and controls. I]. | 1972 | Arch Dermatol Forsch | pmid:4260600 |
Gloor M et al. | [Influence of skin surface lipids on the result of Burckhardt's alkali resistance determination]. | 1972 | Berufsdermatosen | pmid:4262349 |
Cotterill JA et al. | Further observations on the pathogenesis of acne. | 1972 | Br Med J | pmid:4262616 |
Gloor M et al. | Quantity and composition of skin surface lipids and alkaline-resistance in subjects with contact allergy and in healthy controls. | 1972 | Arch Dermatol Forsch | pmid:4264242 |
Tronnier H | [Methodological problems in exogenous and endogenous influencing on the skin surface]. | 1972 | Arch Dermatol Forsch | pmid:4265238 |
Singh EJ et al. | Hydrocarbons in human cervical mucus and the effect of oral contraception. | 1972 | J Reprod Med | pmid:4113025 |
Voogt PA and Van der Horst DJ | Investigations of the capacity of synthesizing 3 -sterols in mollusca. 8. The biosynthesis of 3 -sterols in the pulmonates "Succinea putris" and "Arianta arbustorum". | 1972 | Arch. Int. Physiol. Biochim. | pmid:4114875 |
Sipe JD and Holmlund CE | A comparison of the effects of some hypocholesteremic compounds on squalene metabolism in Tetrahymena pyriformis and rat liver. | 1972 | Biochim. Biophys. Acta | pmid:4116026 |