(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

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Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Persian Gulf Syndrome D018923 1 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Fasciitis D005208 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Steatorrhea D045602 2 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Boutaud O et al. Retention of the label during the conversion of [3-3H] squalene into (3S)-2,3-oxidosqualene catalyzed by mammalian squalene oxidase. 1995 Biochem. Biophys. Res. Commun. pmid:7887959
Fujita H and Matsuo I In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. 1994 Photodermatol Photoimmunol Photomed pmid:7880759
Someya K et al. The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. 1994 J. Nutr. Sci. Vitaminol. pmid:7844638
Rabiskova M et al. The influence of surface properties on uptake of oil into complex coacervate microcapsules. 1994 J. Pharm. Pharmacol. pmid:7815274
Balliano G et al. Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide. 1994 Antimicrob. Agents Chemother. pmid:7810997
Cattel L et al. 2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. 1995 Lipids pmid:7791532
Abe I and Prestwich GD Identification of the active site of vertebrate oxidosqualene cyclase. 1995 Lipids pmid:7791531
Lees ND et al. Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. 1995 Lipids pmid:7791529
Kamimura N et al. Construction of squalene-accumulating Saccharomyces cerevisiae mutants by gene disruption through homologous recombination. 1994 Appl. Microbiol. Biotechnol. pmid:7765777
Yamamoto A et al. Impaired water barrier function in acne vulgaris. 1995 Arch. Dermatol. Res. pmid:7763094