(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

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Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Steatorrhea D045602 2 associated lipids
Fasciitis D005208 2 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
WOOTTON JM and WRIGHT LD Biosynthesis of squalene by the annelid Lumbricus terrestris. 1960 Nature pmid:13786660
GOODMAN DS and POPJAK G Studies on the biosynthesis of cholesterol. XII. Synthesis of allyl pyrophosphates from mevalonate and their conversion into squalene with liver enzymes. 1960 J. Lipid Res. pmid:13851061
PATTERSON JF Biosynthesis of squalene by rat preputial gland. 1960 Proc. Soc. Exp. Biol. Med. pmid:13733368
SCHOEN H and FAHSOLD W [Studies on the problem of resorption of squalene]. 1960 Klin. Wochenschr. pmid:14443328
MELCHIORRI-SANTOLINI U and RENZINI G [Detection of sterols and squalene in sporigenic bacteria]. 1960 Nov-Dec Nuovi Ann Ig Microbiol pmid:13769177
RENZINI G [Detection of sterols and squalene in B. coli aerogenes]. 1960 Nov-Dec Nuovi Ann Ig Microbiol pmid:13740904
GAYLOR JL Anaerobic conversion of acetate to squalene by rat skin. 1961 Proc. Soc. Exp. Biol. Med. pmid:13704081
GOODMAN DS Studies on the conversion of squalene to sterol with rat liver enzymes. 1961 J. Biol. Chem. pmid:13707027
GOSSELIN L and PODBER-WAGNER E [New observations on the particles interfering in the biosynthesis of squalene from mevalonic acid]. 1961 Arch. Int. Physiol. Biochim. pmid:13707370
SEDEE PD Intermediary metabolism in aseptically reared blowfly larvae, Calliphora erythrocephala (Meig.). I. Buosynthesis of squalene and cholesterol. 1961 Arch. Int. Physiol. Biochim. pmid:13749584