| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Villee CA | Shark oil and medicine. | 1970 | N. Engl. J. Med. | pmid:5462581 |
| Miettinen TA et al. | Serum squalene and methyl sterols. | 1970 | N. Engl. J. Med. | pmid:5470273 |
| Peter G et al. | [Gas chromatographic examinations of sebaceous gland lipids. I. Total lipid determination]. | 1970 | Arch Klin Exp Dermatol | pmid:5477881 |
| el-Ibrashy MT and Mansour MH | Hormonal action of certain biologically active compounds in Agrotis ypsilon larvae. | 1970 | Experientia | pmid:5483755 |
| Pochi PE et al. | Sebaceous gland response in man to prolonged total caloric deprivation. | 1970 | J. Invest. Dermatol. | pmid:5483834 |
| Brooks CJ et al. | Lipids of human atheroma. VI. Hydrocarbons of the atheromatous plaque. | 1970 | Lipids | pmid:5488810 |
| Aaronson S | Inhibition of yeast multiplication by hypocholesteremic compounds and its annulment by lipids. | 1971 | Proc. Soc. Exp. Biol. Med. | pmid:5540639 |
| Corey EJ et al. | Conversion of des-6-methyl-2,3-oxidosqualene to 19-norlanosterol by 2,3-oxidosqualene-sterol cyclase. | 1971 | J. Am. Chem. Soc. | pmid:5548348 |
| Altman LJ et al. | Synthesis and conversion of presqualene alcohol to squalene. | 1971 | J. Am. Chem. Soc. | pmid:5550251 |
| Coates RM and Robinson WH | Stereoselective total synthesis of (plus or minus)-presqualene alcohol. | 1971 | J. Am. Chem. Soc. | pmid:5550252 |
| Mulheirn LJ and Caspi E | Mechanism of squalene cyclization. The biosynthesis of fusidic acid. | 1971 | J. Biol. Chem. | pmid:5553407 |
| Cotterill JA et al. | A semiquantitative method for the biochemical analysis of sebum. | 1971 | Br. J. Dermatol. | pmid:5557832 |
| Cunliffe WJ et al. | Variations in skin surface lipid composition with different sampling techniques. I. | 1971 | Br. J. Dermatol. | pmid:5557833 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. II. A comparison of in vitro and in vivo methods. | 1971 | Lipids | pmid:5559874 |
| Peter G et al. | [Gas-chromatography studies on sebaceous gland lipids. II. Composition of sebaceous gland lipids in various age groups]. | 1971 | Arch Dermatol Forsch | pmid:5560856 |
| Jones JP et al. | Lipid biosynthesis in neuron-enriched and glial-enriched fractions of rat brain: sterol formation. | 1971 | Life Sci. II | pmid:5569686 |
| Malhotra HC and Nes WR | The mechanism of introduction of alkyl groups at C-24 of sterols. IV. Inhibition by triparanol. | 1971 | J. Biol. Chem. | pmid:5570429 |
| Peter G and Peter R | [Studies on the composition of palmar skin surface fat in relation to age and its biochemical bases]. | 1971 | Arch Dermatol Forsch | pmid:5571755 |
| Ramsey RB et al. | The biosynthesis of cholesterol and other sterols by brain tissue. I. Subcellular biosynthesis in vitro. | 1971 | Lipids | pmid:5574907 |
| Daly MM | Biosynthesis of squalene and sterols by rat aorta. | 1971 | J. Lipid Res. | pmid:5579265 |
| Boar RB and Damps K | Resolution of 2,3-dihydrosqualene-2,3-diol, 10,11-dihydro-10,11-dihydroxyfarnesyl benzoate, and 6,7-dihydro-6,7-dihydroxygeranyl benzoate. Synthesis of (3R)- and (3S)-2,3-epoxy-2,3-dihydrosqualene. | 1977 | J. Chem. Soc. Perkin Trans. I | pmid:558213 |
| Kishi M et al. | Acid-catalyzed cyclization of squalene oxide. | 1967 | Chem. Pharm. Bull. | pmid:5583148 |
| Schubert K and Schumann W | [On the biosynthesis of sterines]. | 1967 | Acta Biol. Med. Ger. | pmid:5593407 |
| Blumer M | Hydrocarbons in digestive tract and liver of a basking shark. | 1967 | Science | pmid:5609822 |
| Markelova VF and Levachev MM | [Inclusion of C14-acetate in cholesterol and tissue squalene of rats in choline-protein deficiency]. | 1967 Nov-Dec | Vopr Pitan | pmid:5610866 |
| Wepierre J | [Impermeability of mouse skin to tritiated perhydrosqualene]. | 1967 Jul-Aug | Ann Pharm Fr | pmid:5618585 |
| McLaren L et al. | Dense-gas chromatography of nonvolatile substances of high molecular weight. | 1968 | Science | pmid:5634909 |
| Chorbanian AV | Sterol synthesis in the human arterial intima. | 1968 | J. Clin. Invest. | pmid:5637146 |
| Clayton RB et al. | The role of substrate structure in the initiation of enzymic cyclization of squalene 2,3-oxide. Studies with 2,3-cis-1'-norsqual ene 2,3-oxide and 2,3-trans-1'-norsqualene 2,3-oxide. | 1968 | J. Am. Chem. Soc. | pmid:5638313 |
| Rees HH et al. | The biosynthesis of beta-amyrin. Mechanism of squalene cyclization. | 1968 | Biochem. J. | pmid:5639923 |
| Rees HH et al. | Cyclization of 2,3-oxidosqualene to cycloartenol in a cell-free system from higher plants. | 1968 | Tetrahedron Lett. | pmid:5640097 |
| Aaronson S and Fulco L | Effect of hypocholesteremic compounds on bacterial multiplication. | 1968 | J. Gen. Microbiol. | pmid:5640227 |
| Chesterton CJ | Distribution of cholesterol precursors and other lipids among rat liver intracellular structures. | 1968 | J. Biol. Chem. | pmid:5646164 |
| St Clair RW et al. | Synthesis of squalene and sterols by isolated segments of human and pigeon arteries. | 1968 | Exp. Mol. Pathol. | pmid:5647248 |
| Suzue G et al. | Presence of squalene in Staphylococcus. | 1968 | Arch. Biochem. Biophys. | pmid:5650319 |
| Scallen TJ et al. | Enzymatic conversion of squalene to cholesterol by an acetone powder of rat liver microsomes. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5653642 |
| Dada OA et al. | Biosynthesis of phytoquinones. Stereospecific biosynthesis of the polyprenyl side chains of terpenoid quinones and chromanols in maize shoots. | 1968 | Eur. J. Biochem. | pmid:5653765 |
| Wepierre J et al. | Percutaneous absorption and removal by the body fluids of 14C ethyl alcohol, 3H perhydrosqualene and 14C p-cymene. | 1968 | Eur. J. Pharmacol. | pmid:5654669 |
| Locke DC | Chromatographic study of solutions of hydrocarbons in acetonitrile. | 1968 | J. Chromatogr. | pmid:5656425 |
| Bighi C et al. | Interpretation of gas chromatographic data. Hydrocarbons and aromatic compounds on Carbowax 400. | 1968 | J. Chromatogr. | pmid:5658564 |
| Giddings JC et al. | High pressure gas chromatography of nonvolatile species. Compressed gas is used to cause migration of intractable solutes. | 1968 | Science | pmid:5675186 |
| De Souza NJ and Nes WR | Sterols: isolation from a blue-green alga. | 1968 | Science | pmid:5677529 |
| White HB et al. | The occurrence of squalene in kipid of fowlpox virus. | 1968 | J. Biol. Chem. | pmid:5684008 |
| Godtfredsen WO et al. | Biosynthesis of fusidic acid from squalene 2,3-oxide. | 1968 | J. Am. Chem. Soc. | pmid:5688690 |
| Merdinger E et al. | Composition of lipids in extracts of Pullularia pullulans. | 1968 | Can. J. Microbiol. | pmid:5693067 |
| Caspi E et al. | The biosynthesis of tetrahymanol in vitro. | 1968 | Biochem. J. | pmid:5696872 |
| Ackman RG et al. | Unusual occurrence of squalene in a fish, the eulachon Thaleichthys pacificus. | 1968 | Nature | pmid:5701840 |
| Conner RL et al. | Cholesterol inhibition of pentacyclic triterpenoid biosynthesis in Tetrahymena pyriformis. | 1968 | J. Protozool. | pmid:5703082 |
| Frayha GJ | A study of the synthesis and absorption of cholesterol in hydatid cysts (Echinococcus granulosus). | 1968 | Comp. Biochem. Physiol. | pmid:5710286 |
| Suzuki R | Specific requirements of bile salts for absorption of cholesterol from the intestine. | 1968 | Keio J Med | pmid:5715537 |