(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alopecia Areata D000506 6 associated lipids
Alzheimer Disease D000544 76 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
TSAI SC et al. TESTICULAR STEROLS. 1. INCORPORATION OF MEVALONATE AND ACETATE INTO STEROLS BY TESTICULAR TISSUE FROM RATS. 1964 Arch. Biochem. Biophys. pmid:14186739
VAN DEN OORD A THE ABSENCE OF CHOLESTEROL SYNTHESIS IN THE CRAB, CANCER PAGURUS L. 1964 Comp. Biochem. Physiol. pmid:14246359
DILLER ER and HARVEY OA INTERRELATIONSHIP OF STEROL AND FATTY ACID BIOSYNTHESIS IN RAT LIVER SLICES AS RELATED TO DIETARY LIPID. 1964 Biochemistry pmid:14269326
SAMUELSSON B and GOODMAN DS STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL. 1964 J. Biol. Chem. pmid:14114881
ALEXANDER GJ and ALEXANDER RB INHIBITION OF CHOLESTEROL SYNTHESIS IN VIVO BY A CONVULSANT, METRAZOL. 1964 Proc. Soc. Exp. Biol. Med. pmid:14117448
BROOKS SC and GODEFROI VC QUANITITATIVE COLLECTION OF MICRO AMOUNTS OF STEROIDS FROM GAS-LIQUID CHROMATOGRAPHY. 1964 Anal. Biochem. pmid:14134426
LUCY JA and DINGLE JT FAT-SOLUBLE VITAMINS AND BIOLOGICAL MEMBRANES. 1964 Nature pmid:14222261
Krishna G et al. An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene. 1964 Biochem. Biophys. Res. Commun. pmid:4284347
Gosselin L [Utilization of farnesyl pyrophosphate by rat liver microsomes in the absence of nicotinamide adenine dinucleotides]. 1964 Arch. Int. Physiol. Biochim. pmid:4157959
Paroli E [Effect of beta-carotene and of squalene on analgesia and respiratory depression caused by morphine]. 1964 Boll. Soc. Ital. Biol. Sper. pmid:5877121