Clark TW et al. |
Trial of 2009 influenza A (H1N1) monovalent MF59-adjuvanted vaccine. |
2009 |
N. Engl. J. Med. |
pmid:19745215
|
Gallin JI et al. |
Increased serum levels of seualene in patients with acute influenza. |
1970 |
N. Engl. J. Med. |
pmid:5442630
|
Villee CA |
Shark oil and medicine. |
1970 |
N. Engl. J. Med. |
pmid:5462581
|
Chen G et al. |
Optimization of nitrogen source for enhanced production of squalene from thraustochytrid Aurantiochytrium sp. |
2010 |
N Biotechnol |
pmid:20412873
|
Voyron S et al. |
Antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase. |
2010 |
Mycoses |
pmid:19549106
|
Airaudi D et al. |
In vitro susceptibility of fungi to acyclic inhibitors of 2,3-oxidosqualene cyclases. |
1996 Jan-Feb |
Mycoses |
pmid:8786759
|
Airaudi D et al. |
Preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes. |
1995 Jul-Aug |
Mycoses |
pmid:8559196
|
Campagnac E et al. |
Fenpropimorph slows down the sterol pathway and the development of the arbuscular mycorrhizal fungus Glomus intraradices. |
2009 |
Mycorrhiza |
pmid:19340463
|
Hamdan JS and Casali AK |
Effect of amphotericin B on the lipids of yeast cells of Sporothrix schenckii. |
1996-1997 |
Mycopathologia |
pmid:9276941
|
Fan SR et al. |
Squalene inhibits sodium arsenite-induced sister chromatid exchanges and micronuclei in Chinese hamster ovary-K1 cells. |
1996 |
Mutat. Res. |
pmid:8692222
|
Huang ZR et al. |
Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. |
2009 |
Molecules |
pmid:19169201
|
Fox CB |
Squalene emulsions for parenteral vaccine and drug delivery. |
2009 |
Molecules |
pmid:19783926
|
Lokvam J and Fine PV |
An oxidized squalene derivative from Protium subserratum Engl. (Engl.) growing in Peru. |
2012 |
Molecules |
pmid:22706374
|
Piccialli V et al. |
Isolation of a bis-iodurated tetra-THF as a trace product from the oxidation of squalene with RuOâ‚„ and its double ring expansion to a novel bis-THF-bis-THP compound. |
2011 |
Molecules |
pmid:21709619
|
AÄimoviÄ J and Rozman D |
Steroidal triterpenes of cholesterol synthesis. |
2013 |
Molecules |
pmid:23558541
|
Shenoy SD et al. |
Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes. |
2004 |
Mol. Pharmacol. |
pmid:15102959
|
Reddy LH et al. |
Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor. |
2009 Sep-Oct |
Mol. Pharm. |
pmid:19634915
|
Allison AC and Byars NE |
Immunological adjuvants: desirable properties and side-effects. |
1991 |
Mol. Immunol. |
pmid:1850114
|
Karst F and Lacroute F |
Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway. |
1977 |
Mol. Gen. Genet. |
pmid:200835
|
GarcÃa-Román N et al. |
Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. |
2001 |
Mol. Cell. Neurosci. |
pmid:11178870
|
Popják G and Agnew WS |
Squalene synthetase. |
1979 |
Mol. Cell. Biochem. |
pmid:41173
|
Lamb DC et al. |
Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis. |
2007 |
Mol. Biol. Evol. |
pmid:17567593
|
Vriet C et al. |
From squalene to brassinolide: the steroid metabolic and signaling pathways across the plant kingdom. |
2013 |
Mol Plant |
pmid:23761349
|
Granados-Principal S et al. |
Squalene ameliorates atherosclerotic lesions through the reduction of CD36 scavenger receptor expression in macrophages. |
2012 |
Mol Nutr Food Res |
pmid:22648620
|
O'Hagan DT et al. |
Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. |
1997 |
Mol Med Today |
pmid:9060004
|
HADORN H and JUNGKUNZ R |
[Further studies on squalene. 4]. |
1950 |
Mitt Lebensmittelunters Hyg |
pmid:14806249
|
Perzl M et al. |
Squalene-hopene cyclase from Bradyrhizobium japonicum: cloning, expression, sequence analysis and comparison to other triterpenoid cyclases. |
1997 |
Microbiology (Reading, Engl.) |
pmid:9141686
|
Kerwin JL et al. |
Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum. |
1995 |
Microbiology (Reading, Engl.) |
pmid:7704271
|
Huang MH et al. |
Enhancement of potent antibody and T-cell responses by a single-dose, novel nanoemulsion-formulated pandemic influenza vaccine. |
2009 May-Jun |
Microbes Infect. |
pmid:19344782
|
Colombatti M and Dosio F |
Synthesis of monensin derivatives and their effect on the activity of ricin A-chain immunotoxins. |
2001 |
Methods Mol. Biol. |
pmid:11217376
|
Allison AC |
Squalene and squalane emulsions as adjuvants. |
1999 |
Methods |
pmid:10525443
|
Nakano M et al. |
3-(4'-methyl-1'-naphthyl)propionic acid, 1',4'-endoperoxide for dioxygenation of squalene and for bacterial killing. |
2000 |
Meth. Enzymol. |
pmid:10907513
|
Maes D et al. |
Noninvasive techniques for measuring oxidation products on the surface of human skin. |
2000 |
Meth. Enzymol. |
pmid:10907548
|
Nishino T and Katsuki H |
Formation of 12-cis-dehydrosqualene catalyzed by squalene synthetase. |
1985 |
Meth. Enzymol. |
pmid:3894880
|
Cuzzopoli M et al. |
Effect of nephrectomy and cholesterol feeding on the metabolism of intravenously administered DL-mevalonate in the rat. |
1972 |
Metab. Clin. Exp. |
pmid:4641957
|
Gylling H et al. |
Hypolipidemic effect and mechanism of ketoconazole without and with cholestyramine in familial hypercholesterolemia. |
1991 |
Metab. Clin. Exp. |
pmid:1984567
|
Relas H et al. |
Effect of stanol ester on postabsorptive squalene and retinyl palmitate. |
2000 |
Metab. Clin. Exp. |
pmid:10778871
|
Salvioli G et al. |
Relationships between squalene and cholesterol in bile: effect of ursodeoxycholic acid administration in patients with radiolucent gallstones. |
1984 |
Metab. Clin. Exp. |
pmid:6738365
|
De Luca C and Valacchi G |
Surface lipids as multifunctional mediators of skin responses to environmental stimuli. |
2010 |
Mediators Inflamm. |
pmid:20981292
|
Saadatzadeh MR et al. |
Production of the mycelial phase of Malassezia in vitro. |
2001 |
Med. Mycol. |
pmid:11798054
|
Hernández-GarcÃa I et al. |
[Adverse events after administration of A/H1N1 vaccine to patients]. |
2011 |
Med Clin (Barc) |
pmid:20199781
|
Iannitti T and Palmieri B |
An update on the therapeutic role of alkylglycerols. |
2010 |
Mar Drugs |
pmid:20948908
|
Borchman D et al. |
Confirmation of the presence of squalene in human eyelid lipid by heteronuclear single quantum correlation spectroscopy. |
2013 |
Lipids |
pmid:24081494
|
Strandberg TE |
Sterol synthesis from biliary squalene in the jejunal mucosa of the rat in vivo. |
1983 |
Lipids |
pmid:6621260
|
Mercer EI |
Sterol biosynthesis inhibitors: their current status and modes of action. |
1991 |
Lipids |
pmid:1779706
|
Bell FP and Hubert EV |
Evidence that chlorpromazine inhibits sterologenesis at post-HMGCoA reductase sites in rat liver, in vitro. |
1983 |
Lipids |
pmid:6633175
|
Johnson RC and Shah SN |
Hepatic cholesterol synthesis from mevalonate and squalwne in rats: effect of feeding cholesterol supplemented diet during weaning and following starvation. |
1974 |
Lipids |
pmid:4444430
|
Yeo HC and Shibamoto T |
Formation of formaldehyde and malonaldehyde by photooxidation of squalene. |
1992 |
Lipids |
pmid:1608304
|
Lau HL et al. |
Simultaneous quantification of free fatty acids, free sterols, squalene, and acylglycerol molecular species in palm oil by high-temperature gas chromatography--flame ionization detection. |
2005 |
Lipids |
pmid:16094863
|
Choo YM et al. |
Application of supercritical fluid chromatography in the quantitative analysis of minor components (carotenes, vitamin E, sterols, and squalene) from palm oil. |
2005 |
Lipids |
pmid:16028723
|
Cherayil GD et al. |
Abnormal lipid composition of fat tissue in human mesenteric panniculitis. |
1981 |
Lipids |
pmid:6163941
|
Strandberg TE et al. |
Effects of cholestyramine and squalene feeding on hepatic and serum plant sterols in the rat. |
1989 |
Lipids |
pmid:2586228
|
Eilenberg H and Shechter I |
A possible regulatory role of squalene epoxidase in Chinese hamster ovary cells. |
1984 |
Lipids |
pmid:6087072
|
Scallen TJ et al. |
Studies on the enzymatic synthesis of cholesterol: use of a liver acetone powder. |
1971 |
Lipids |
pmid:4396848
|
Shah SN |
Regulation of hepatic cholesterol synthesis from mevalonate in suckling and weaned rats. |
1973 |
Lipids |
pmid:4713377
|
McKean ML and Nes WR |
Delayed conversion of squalene to sterols during development of Pinus pinea seeds. |
1977 |
Lipids |
pmid:853880
|
Oliaro-Bosso S et al. |
Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae. |
2005 |
Lipids |
pmid:16477810
|
Viola F et al. |
Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase. |
2000 |
Lipids |
pmid:10783007
|
Matthan NR et al. |
Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women. |
2000 |
Lipids |
pmid:11026626
|
Nes WR |
Regulation of the sequencing in sterol biosynthesis. |
1971 |
Lipids |
pmid:4997338
|
Cattel L et al. |
The squalene-2,3-epoxide cyclase as a model for the development of new drugs. |
1986 |
Lipids |
pmid:3515096
|
Nes WR |
Role of sterols in membranes. |
1974 |
Lipids |
pmid:4607429
|
Koivisto PV and Miettinen TA |
Increased amounts of cholesterol precursors in lipoproteins after ileal exclusion. |
1988 |
Lipids |
pmid:3200122
|
Lees ND et al. |
Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae--a review. |
1995 |
Lipids |
pmid:7791529
|
Abe I and Prestwich GD |
Identification of the active site of vertebrate oxidosqualene cyclase. |
1995 |
Lipids |
pmid:7791531
|
Cattel L et al. |
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors. |
1995 |
Lipids |
pmid:7791532
|
Buttke TM et al. |
Regulation of squalene epoxidase activity by membrane fatty acid composition in yeast. |
1988 |
Lipids |
pmid:3280941
|
Balliano G et al. |
3-Carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase. |
1993 |
Lipids |
pmid:8246689
|
Storm HM et al. |
Radioprotection of mice by dietary squalene. |
1993 |
Lipids |
pmid:8355581
|
Milla P et al. |
19-Azasqualene-2,3-epoxide and its N-oxide: metabolic fate and inhibitory effect on sterol biosynthesis in Saccharomyces cerevisiae. |
1999 |
Lipids |
pmid:10478925
|
Mallory FB and Conner RL |
Dehydrogenation and dealkylation of various sterols by Tetrahymena pyriformis. |
1971 |
Lipids |
pmid:4102490
|
Lutsky BN et al. |
In vitro incorporation of 14C-acetate into lipids of hamster flank organ (costovertebral organ) sebaceous glands and epidermis. |
1974 |
Lipids |
pmid:4810504
|
Brooks CJ et al. |
Lipids of human atheroma. VI. Hydrocarbons of the atheromatous plaque. |
1970 |
Lipids |
pmid:5488810
|
Ceruti M et al. |
Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases. |
2001 |
Lipids |
pmid:11485168
|
Tilvis RS and Miettinen TA |
Dietary squalene increases tissue sterols and fecal bile acids in the rat. |
1983 |
Lipids |
pmid:6835033
|
Tilvis RS and Miettinen TA |
Absorption and metabolic fate of dietary 3H-squalene in the rat. |
1983 |
Lipids |
pmid:6855483
|
Ramsey RB et al. |
The biosynthesis of cholesterol and other sterols by brain tissue. II. A comparison of in vitro and in vivo methods. |
1971 |
Lipids |
pmid:5559874
|
Porcellati G et al. |
Inhibition of cholesterol synthesis by beta-benzal butyric acid and derivatives. |
1969 |
Lipids |
pmid:5785689
|
Ramsey RB et al. |
The biosynthesis of cholesterol and other sterols by brain tissue. I. Subcellular biosynthesis in vitro. |
1971 |
Lipids |
pmid:5574907
|
Van Sickle WA et al. |
Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture. |
1992 |
Lipids |
pmid:1326069
|
Morin RJ et al. |
Effect of age and cholestyramine feeding on rat liver 3-hydroxy-3-methyl glutaryl CoA reductase, sterol carrier protein 1 and sterol carrier protein 2 activities. |
1982 |
Lipids |
pmid:7121212
|
Nakagawa K et al. |
gamma-Tocotrienol reduces squalene hydroperoxide-induced inflammatory responses in HaCaT keratinocytes. |
2010 |
Lipids |
pmid:20714817
|
Lewis RW |
Effect of alimentation on human serum squalene levels. |
1976 |
Lipids |
pmid:180373
|
Lindholm JS and Downing DT |
Occurrence of squalene in skin surface lipids of the otter, the beaver and the kinkajou. |
1980 |
Lipids |
pmid:7219074
|
Bell FP and Hubert EV |
Stimulation of hepatic squalene and triglyceride synthesis by dimethylsulfoxide, in vitro. |
1982 |
Lipids |
pmid:7162368
|
Kushwaha SC and Kates M |
Lipid composition of Neurospora crassa. |
1976 |
Lipids |
pmid:136584
|
Rocco F et al. |
Conjugated methyl sulfide and phenyl sulfide derivatives of oxidosqualene as inhibitors of oxidosqualene and squalene-hopene cyclases. |
2003 |
Lipids |
pmid:12784859
|
Srikantaiah MV et al. |
Inhibition of rat hepatic sterol formation from squalene by plasma lipoproteins. |
1980 |
Lipids |
pmid:7432102
|
Bell FP |
Inhibition of hepatic sterol and squalene biosynthesis in rats fed di-i-ethylhexyl phthalate. |
1976 |
Lipids |
pmid:994746
|
Johnson RC and Shah SN |
Binding of squalene, lanosterol, desmosterol, and cholesterol to proteins in brain and liver 105,000 g supernatant fractions: evidence for specific binding sites. |
1976 |
Lipids |
pmid:994754
|
Peyronel D et al. |
Fatty acid and squalene compositions of Mediterranean Centrophorus SPP egg and liver oils in relation to age. |
1984 |
Lipids |
pmid:6503627
|
Egwim PO and Kummerow FA |
In vitro hepatic cholesterogenesis in rats fed corn oil and fat-free diets. |
1973 |
Life Sci. II |
pmid:4708203
|
Jones JP et al. |
Lipid biosynthesis in neuron-enriched and glial-enriched fractions of rat brain: sterol formation. |
1971 |
Life Sci. II |
pmid:5569686
|
Scallen TJ et al. |
Sterol carrier protein hypothesis: requirement for three substrate-specific soluble proteins in liver cholesterol biosynthesis. |
1975 |
Life Sci. |
pmid:165341
|
Miettinen TA |
Serum squalene and methyl sterols as indicators of cholesterol synthesis in vivo. |
1969 |
Life Sci. |
pmid:5801489
|
Foti L et al. |
Biosynthesis of cholesterol from long-chain fatty acids in cell-free systems from rat liver. |
1969 |
Life Sci. |
pmid:5804653
|
Rasch MR et al. |
Chains, sheets, and droplets: assemblies of hydrophobic gold nanocrystals with saturated phosphatidylcholine lipid and squalene. |
2012 |
Langmuir |
pmid:23033891
|
Arias JL et al. |
Magnetoresponsive squalenoyl gemcitabine composite nanoparticles for cancer active targeting. |
2008 |
Langmuir |
pmid:18540685
|
Shrestha LK et al. |
Effect of water on foaming properties of diglycerol fatty acid ester-oil systems. |
2007 |
Langmuir |
pmid:17523681
|
Gilmore SF et al. |
Role of squalene in the organization of monolayers derived from lipid extracts of Halobacterium salinarum. |
2013 |
Langmuir |
pmid:23713788
|