| MeSH term | MeSH ID | Detail |
|---|---|---|
| Persian Gulf Syndrome | D018923 | 1 associated lipids |
| Hemorrhagic Septicemia, Viral | D031941 | 1 associated lipids |
| Steatorrhea | D045602 | 2 associated lipids |
| Fasciitis | D005208 | 2 associated lipids |
| Ossification, Heterotopic | D009999 | 2 associated lipids |
| Pneumonia, Lipid | D011017 | 2 associated lipids |
| Gallbladder Diseases | D005705 | 3 associated lipids |
| Exostoses, Multiple Hereditary | D005097 | 3 associated lipids |
| Simian Acquired Immunodeficiency Syndrome | D016097 | 4 associated lipids |
| Hyperlipoproteinemia Type III | D006952 | 4 associated lipids |
| Coronavirus Infections | D018352 | 4 associated lipids |
| Viremia | D014766 | 4 associated lipids |
| Lipodystrophy | D008060 | 4 associated lipids |
| Parvoviridae Infections | D010322 | 4 associated lipids |
| Keratitis, Herpetic | D016849 | 5 associated lipids |
| Leukemia, Hairy Cell | D007943 | 5 associated lipids |
| Parasitemia | D018512 | 5 associated lipids |
| Tinea Versicolor | D014010 | 5 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nguyen HT et al. | Molecular characterization of Glycine max squalene synthase genes in seed phytosterol biosynthesis. | 2013 | Plant Physiol. Biochem. | pmid:24036394 |
| Vono M et al. | The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24324152 |
| Pannkuk EL et al. | Sebaceous lipid profiling of bat integumentary tissues: quantitative analysis of free Fatty acids, monoacylglycerides, squalene, and sterols. | 2013 | Chem. Biodivers. | pmid:24327437 |
| Tegenge MA and Mitkus RJ | A physiologically-based pharmacokinetic (PBPK) model of squalene-containing adjuvant in human vaccines. | 2013 | J Pharmacokinet Pharmacodyn | pmid:23912214 |
| Rappuoli R | Vaccine adjuvants: the future is bright. Interview by Jenaid Rees. | 2013 | Expert Rev Vaccines | pmid:23829664 |
| Trung Bui D et al. | Polymer prodrug nanoparticles based on naturally occurring isoprenoid for anticancer therapy. | 2013 | Biomacromolecules | pmid:23829862 |
| Bruun Laursen A | [Catastrophic consequences of Pandemrix swine flu vaccine containing squalene]. | 2013 | Ugeskr. Laeg. | pmid:23833781 |
| Mølbak K | [Squalene unlikely sinner]. | 2013 | Ugeskr. Laeg. | pmid:23833782 |
| Gefenaite G et al. | Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination. | 2013 | PLoS ONE | pmid:23840413 |
| Ueda D et al. | Cyclization of squalene from both termini: identification of an onoceroid synthase and enzymatic synthesis of ambrein. | 2013 | J. Am. Chem. Soc. | pmid:24274794 |