(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Persian Gulf Syndrome D018923 1 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Ossification, Heterotopic D009999 2 associated lipids
Fasciitis D005208 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Steatorrhea D045602 2 associated lipids
Gallbladder Diseases D005705 3 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Hyperlipoproteinemia Type III D006952 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Lipodystrophy D008060 4 associated lipids
Viremia D014766 4 associated lipids
Tinea Versicolor D014010 5 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Parasitemia D018512 5 associated lipids
Alopecia Areata D000506 6 associated lipids
Chronic Disease D002908 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

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Authors Title Published Journal PubMed Link
Cataldo DM and Van Nest G The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. 1997 Vaccine pmid:9364672
Stephenson I et al. Boosting immunity to influenza H5N1 with MF59-adjuvanted H5N3 A/Duck/Singapore/97 vaccine in a primed human population. 2003 Vaccine pmid:12639491
Romera SA et al. Adjuvant effects of sulfolipo-cyclodextrin in a squalane-in-water and water-in-mineral oil emulsions for BHV-1 vaccines in cattle. 2000 Vaccine pmid:10924795
Süli J et al. Experimental squalene adjuvant. I. Preparation and testing of its effectiveness. 2004 Vaccine pmid:15308373
Benísek Z et al. Experimental squalene adjuvant. II. Harmlessness and local reactogenity. 2004 Vaccine pmid:15308374
Morel S et al. Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity. 2011 Vaccine pmid:21256188
de Roux A et al. Impact of corticosteroids on the immune response to a MF59-adjuvanted influenza vaccine in elderly COPD-patients. 2006 Vaccine pmid:16288937
Candela S et al. An early (3-6 weeks) active surveillance study to assess the safety of pandemic influenza vaccine Focetria in a province of Emilia-Romagna region, Italy - part one. 2013 Vaccine pmid:22766247
Ventura R et al. Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia. 2013 Vaccine pmid:22884665
Moro ML et al. A population based cohort study to assess the safety of pandemic influenza vaccine Focetria in Emilia-Romagna region, Italy - part two. 2013 Vaccine pmid:22885015