| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acne Vulgaris | D000152 | 35 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Cholestasis | D002779 | 23 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tascon M et al. | Determinations of gas-liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane. | 2013 | J Chromatogr A | pmid:23659974 |
| Mann JF et al. | Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection. | 2013 | J Control Release | pmid:23774102 |
| Vesikari T et al. | Assessment of squalene adjuvanted and non-adjuvanted vaccines against pandemic H1N1 influenza in children 6 months to 17 years of age. | 2012 | Hum Vaccin Immunother | pmid:22906943 |
| Della Cioppa G et al. | Superior immunogenicity of seasonal influenza vaccines containing full dose of MF59 (®) adjuvant: results from a dose-finding clinical trial in older adults. | 2012 | Hum Vaccin Immunother | pmid:22426371 |
| Ikematsu H et al. | Evaluation of immune response following one dose of an AS03A-adjuvanted H1N1 2009 pandemic influenza vaccine in Japanese adults 65 years of age or older. | 2012 | Hum Vaccin Immunother | pmid:22854661 |
| Vesikari T et al. | Homologous and heterologous antibody responses to a one-year booster dose of an MF59(®) adjuvanted A/H5N1 pre-pandemic influenza vaccine in pediatric subjects. | 2012 | Hum Vaccin Immunother | pmid:22777094 |
| Bencharitiwong R et al. | In vitro assessment of the allergenicity of novel MF59-adjuvanted pandemic H1N1 influenza vaccine produced in dog kidney cells. | 2012 | Hum Vaccin Immunother | pmid:22777093 |
| Siegrist CA et al. | Responses of solid organ transplant recipients to the AS03-adjuvanted pandemic influenza vaccine. | 2012 | Antivir. Ther. (Lond.) | pmid:22544169 |
| Yang M et al. | MF59 formulated with CpG ODN as a potent adjuvant of recombinant HSP65-MUC1 for inducing anti-MUC1+ tumor immunity in mice. | 2012 | Int. Immunopharmacol. | pmid:22595192 |
| Cabrera-Vique C et al. | Bioactive compounds and nutritional significance of virgin argan oil--an edible oil with potential as a functional food. | 2012 | Nutr. Rev. | pmid:22537213 |
| Stella B et al. | Nonpolymeric nanoassemblies for ocular administration of acyclovir: pharmacokinetic evaluation in rabbits. | 2012 | Eur J Pharm Biopharm | pmid:22008147 |
| Nakazawa A et al. | Optimization of culture conditions of the thraustochytrid Aurantiochytrium sp. strain 18W-13a for squalene production. | 2012 | Bioresour. Technol. | pmid:22023965 |
| Niehaus TD et al. | Functional identification of triterpene methyltransferases from Botryococcus braunii race B. | 2012 | J. Biol. Chem. | pmid:22241476 |
| Iorio AM et al. | Influenza viruses and cross-reactivity in healthy adults: humoral and cellular immunity induced by seasonal 2007/2008 influenza vaccination against vaccine antigens and 2009 A(H1N1) pandemic influenza virus. | 2012 | Vaccine | pmid:22245606 |
| Ambrose CS and Belshe RB | Influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22276839 |
| Heikkinen T and Heinonen S | Influenza vaccine in young children. | 2012 | N. Engl. J. Med. | pmid:22276840 |
| Gasparini R et al. | Aflunov(®): a prepandemic influenza vaccine. | 2012 | Expert Rev Vaccines | pmid:22309663 |
| Spanova M et al. | Influence of squalene on lipid particle/droplet and membrane organization in the yeast Saccharomyces cerevisiae. | 2012 | Biochim. Biophys. Acta | pmid:22342273 |
| Palma P et al. | Safety and immunogenicity of a monovalent MF59®-adjuvanted A/H1N1 vaccine in HIV-infected children and young adults. | 2012 | Biologicals | pmid:22261282 |
| Heikkinen T et al. | Safety of MF59-adjuvanted A/H1N1 influenza vaccine in pregnancy: a comparative cohort study. | 2012 | Am. J. Obstet. Gynecol. | pmid:22939717 |
| Mannino S et al. | Effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy. | 2012 | Am. J. Epidemiol. | pmid:22940713 |
| Wu S et al. | Engineering triterpene metabolism in tobacco. | 2012 | Planta | pmid:22729821 |
| Langley JM et al. | Randomized, multicenter trial of a single dose of AS03-adjuvanted or unadjuvanted H1N1 2009 pandemic influenza vaccine in children 6 months to <9 years of age: safety and immunogenicity. | 2012 | Pediatr. Infect. Dis. J. | pmid:22801094 |
| Block SL et al. | Dose-range study of MF59-adjuvanted versus nonadjuvanted monovalent A/H1N1 pandemic influenza vaccine in six- to less than thirty-six-month-old children. | 2012 | Pediatr. Infect. Dis. J. | pmid:22481427 |
| Sémiramoth N et al. | Self-assembled squalenoylated penicillin bioconjugates: an original approach for the treatment of intracellular infections. | 2012 | ACS Nano | pmid:22482704 |
| Langley JM et al. | Safety and immunogenicity of 2010-2011 H1N12009-containing trivalent inactivated influenza vaccine in children 12-59 months of age previously given AS03-adjuvanted H1N12009 pandemic vaccine: a PHAC/CIHR Influenza Research Network (PCIRN) study. | 2012 | Vaccine | pmid:22469860 |
| Fukase H et al. | Assessment of the immunogenicity and safety of varying doses of an MF59®-adjuvanted cell culture-derived A/H1N1 pandemic influenza vaccine in Japanese paediatric, adult and elderly subjects. | 2012 | Vaccine | pmid:22472791 |
| Suthiwong J et al. | A new phenolic compound from the stem of Hymenocardia wallichii. | 2012 | J Asian Nat Prod Res | pmid:22423644 |
| Zhang XH et al. | Chemical composition of volatile oils from the pericarps of Indian sandalwood (Santalum album) by different extraction methods. | 2012 | Nat Prod Commun | pmid:22428257 |
| Guzmán Herrador BR et al. | Usefulness of health registries when estimating vaccine effectiveness during the influenza A(H1N1)pdm09 pandemic in Norway. | 2012 | BMC Infect. Dis. | pmid:22429643 |
| Hatz C et al. | A randomized clinical trial to identify the optimal antigen and MF59(®) adjuvant dose of a monovalent A/H1N1 pandemic influenza vaccine in healthy adult and elderly subjects. | 2012 | Vaccine | pmid:22446638 |
| Lai RP et al. | Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants. | 2012 | PLoS ONE | pmid:22509385 |
| Marinaro M et al. | A caprine herpesvirus 1 vaccine adjuvanted with MF59â„¢ protects against vaginal infection and interferes with the establishment of latency in goats. | 2012 | PLoS ONE | pmid:22511971 |
| Cosco D et al. | Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases. | 2012 | Int J Nanomedicine | pmid:22679366 |
| O'Hagan DT et al. | The mechanism of action of MF59 - an innately attractive adjuvant formulation. | 2012 | Vaccine | pmid:22682289 |
| Lokvam J and Fine PV | An oxidized squalene derivative from Protium subserratum Engl. (Engl.) growing in Peru. | 2012 | Molecules | pmid:22706374 |
| Yu S et al. | Novel Th1-biased adjuvant, SPO1, enhances mucosal and systemic immunogenicity of vaccines administered intranasally in mice. | 2012 | Vaccine | pmid:22709954 |
| Fox CB et al. | Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines. | 2012 | Clin. Vaccine Immunol. | pmid:22896687 |
| Reynales H et al. | A prospective observational safety study on MF59(®) adjuvanted cell culture-derived vaccine, Celtura(®) during the A/H1N1 (2009) influenza pandemic. | 2012 | Vaccine | pmid:22902681 |
| Desmaële D et al. | Squalenoylation: a generic platform for nanoparticular drug delivery. | 2012 | J Control Release | pmid:21840355 |
| Naziri E et al. | Recovery of squalene from wine lees using ultrasound assisted extraction-a feasibility study. | 2012 | J. Agric. Food Chem. | pmid:22888984 |
| Peric M et al. | Electron paramagnetic resonance line shifts and line shape changes due to heisenberg spin exchange and dipole-dipole interactions of nitroxide free radicals in liquids 8. Further experimental and theoretical efforts to separate the effects of the two interactions. | 2012 | J Phys Chem A | pmid:22288424 |
| Czajka H et al. | A phase II, randomised clinical trial to demonstrate the non-inferiority of low-dose MF59-adjuvanted pre-pandemic A/H5N1 influenza vaccine in adult and elderly subjects. | 2012 | J Prev Med Hyg | pmid:23362618 |
| Takami T et al. | A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast. | 2012 | PLoS ONE | pmid:23145048 |
| Langley JM et al. | A randomized, controlled non-inferiority trial comparing A(H1N1)pmd09 vaccine antigen, with and without AS03 adjuvant system, co-administered or sequentially administered with an inactivated trivalent seasonal influenza vaccine. | 2012 | BMC Infect. Dis. | pmid:23110320 |
| Bihari I et al. | Assessment of antigen-specific and cross-reactive antibody responses to an MF59-adjuvanted A/H5N1 prepandemic influenza vaccine in adult and elderly subjects. | 2012 | Clin. Vaccine Immunol. | pmid:23081815 |
| Tetsutani K and Ishii KJ | Adjuvants in influenza vaccines. | 2012 | Vaccine | pmid:23084848 |
| Liu YT et al. | Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase. | 2012 | Org. Lett. | pmid:23043506 |
| Ta MT et al. | Accumulation of squalene is associated with the clustering of lipid droplets. | 2012 | FEBS J. | pmid:23013491 |
| Nielsen AB et al. | Immune response after one or two doses of pandemic influenza A (H1N1) monovalent, AS03-adjuvanted vaccine in HIV infected adults. | 2012 | Vaccine | pmid:23036498 |