(e,e,e,e)-squalene

(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (e,e,e,e)-squalene?

(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene

MeSH term MeSH ID Detail
Atherosclerosis D050197 85 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Steatorrhea D045602 2 associated lipids
Hemorrhagic Septicemia, Viral D031941 1 associated lipids
Persian Gulf Syndrome D018923 1 associated lipids
Parasitemia D018512 5 associated lipids
Coronavirus Infections D018352 4 associated lipids
Keratitis, Herpetic D016849 5 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Weight Gain D015430 101 associated lipids
Xanthomatosis D014973 17 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Viremia D014766 4 associated lipids
Tinea Versicolor D014010 5 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Rosacea D012393 13 associated lipids
Psoriasis D011565 47 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (e,e,e,e)-squalene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (e,e,e,e)-squalene?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (e,e,e,e)-squalene?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (e,e,e,e)-squalene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (e,e,e,e)-squalene

Download all related citations
Per page 10 20 50 100 | Total 1766
Authors Title Published Journal PubMed Link
Naughton C et al. Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures. 2013 Nat. Struct. Mol. Biol. pmid:23416946
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Morimoto Y et al. Biomimetic epoxide-opening cascades of oxasqualenoids triggered by hydrolysis of the terminal epoxide. 2013 Org. Lett. pmid:23721415
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Lange S et al. Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors. 2013 Eur J Med Chem pmid:23583910
McElhaney JE et al. AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial. 2013 Lancet Infect Dis pmid:23518156
Ledgerwood JE AS03-adjuvanted influenza vaccine in elderly people. 2013 Lancet Infect Dis pmid:23518157
Hillaireau H et al. Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies. 2013 Biomaterials pmid:23562054
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Segura-Velázquez R et al. Influenza vaccine: development of a novel intranasal and subcutaneous recombinant adjuvant. 2013 Vaccine pmid:23746458
Lin YS et al. A real-time impedance-sensing chip for the detection of emulsion phase separation. 2013 Electrophoresis pmid:23765861
Mann JF et al. Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection. 2013 J Control Release pmid:23774102