(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pannkuk EL et al. | Sebaceous lipid profiling of bat integumentary tissues: quantitative analysis of free Fatty acids, monoacylglycerides, squalene, and sterols. | 2013 | Chem. Biodivers. | pmid:24327437 |
Bruun Laursen A | [Catastrophic consequences of Pandemrix swine flu vaccine containing squalene]. | 2013 | Ugeskr. Laeg. | pmid:23833781 |
Vesikari T et al. | Homologous and heterologous antibody responses to a one-year booster dose of an MF59(®) adjuvanted A/H5N1 pre-pandemic influenza vaccine in pediatric subjects. | 2012 | Hum Vaccin Immunother | pmid:22777094 |
Spanova M et al. | Influence of squalene on lipid particle/droplet and membrane organization in the yeast Saccharomyces cerevisiae. | 2012 | Biochim. Biophys. Acta | pmid:22342273 |
Palma P et al. | Safety and immunogenicity of a monovalent MF59®-adjuvanted A/H1N1 vaccine in HIV-infected children and young adults. | 2012 | Biologicals | pmid:22261282 |
Heikkinen T et al. | Safety of MF59-adjuvanted A/H1N1 influenza vaccine in pregnancy: a comparative cohort study. | 2012 | Am. J. Obstet. Gynecol. | pmid:22939717 |
Cosco D et al. | Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases. | 2012 | Int J Nanomedicine | pmid:22679366 |
O'Hagan DT et al. | The mechanism of action of MF59 - an innately attractive adjuvant formulation. | 2012 | Vaccine | pmid:22682289 |
Lokvam J and Fine PV | An oxidized squalene derivative from Protium subserratum Engl. (Engl.) growing in Peru. | 2012 | Molecules | pmid:22706374 |
Ta MT et al. | Accumulation of squalene is associated with the clustering of lipid droplets. | 2012 | FEBS J. | pmid:23013491 |