(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kribii R et al. | Cloning and characterization of the Arabidopsis thaliana SQS1 gene encoding squalene synthase--involvement of the C-terminal region of the enzyme in the channeling of squalene through the sterol pathway. | 1997 | Eur. J. Biochem. | pmid:9363754 |
Cataldo DM and Van Nest G | The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. | 1997 | Vaccine | pmid:9364672 |
Tomasi M et al. | Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. | 1997 | Eur. J. Immunol. | pmid:9368632 |
Salamon Z et al. | Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties. | 1997 | Biophys. J. | pmid:9370473 |
Toews AD et al. | Tellurium causes dose-dependent coordinate down-regulation of myelin gene expression. | 1997 | Brain Res. Mol. Brain Res. | pmid:9387870 |
Gloor M et al. | Biochemical and physiological parameters on the healthy skin surface of patients with common warts. | 1976 | Dermatologica | pmid:939341 |
Law S et al. | Skin surface lipids inhibit adherence of Candida albicans to stratum corneum. | 1997 | Dermatology (Basel) | pmid:9407165 |
Newmark HL | Squalene, olive oil, and cancer risk: a review and hypothesis. | 1997 | Cancer Epidemiol. Biomarkers Prev. | pmid:9419410 |
Ceruti M et al. | 29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. | 1998 | J. Med. Chem. | pmid:9484504 |
Rao CV et al. | Chemopreventive effect of squalene on colon cancer. | 1998 | Carcinogenesis | pmid:9498278 |