(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Volkov GL et al. | [In vitro biosynthesis of cholesterol and its precursors in the osseous tissue of rats]. | 1976 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:1005362 |
Gajkowska B et al. | The experimental squalene encephaloneuropathy in the rat. | 1999 | Exp. Toxicol. Pathol. | pmid:10048717 |
Takeuchi M et al. | Corynebacterium terpenotabidum sp. nov., a bacterium capable of degrading squalene. | 1999 | Int. J. Syst. Bacteriol. | pmid:10028267 |
Cooper MF et al. | Effects of testosterone and alpha-melanocyte-stimulating hormone on preputial-gland (sebaceous) activity. | 1976 | Biochem. Soc. Trans. | pmid:1001771 |
Bowden PE et al. | Effects of 5alpha-reduced androgens on preputial-gland size and lipogenic activity. | 1976 | Biochem. Soc. Trans. | pmid:1001770 |
Bell FP | Biosynthesis of various sterols, sterol esters, and squalene from [14C]mevalonate by normal swine intima and media in vitro: a comparative study. | 1976 | Exp. Mol. Pathol. | pmid:1001402 |