(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Taylor RF and Ikawa M | Gas chromatography of carotenoids. | 1971 | Anal. Biochem. | pmid:5130948 |
ROTHBLAT GH et al. | A quantitative colorimetric assay for squalene. | 1962 | Anal. Biochem. | pmid:14494417 |
Tait RM | Development of a radiometric spot-wash assay for squalene synthase. | 1992 | Anal. Biochem. | pmid:1416027 |
Sun S et al. | The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. | 2005 | Anal. Biochem. | pmid:15582556 |
Mountfort KA et al. | Identification of oxidation products of squalene in solution and in latent fingerprints by ESI-MS and LC/APCI-MS. | 2007 | Anal. Chem. | pmid:17343365 |
Young TE and Maggs RJ | The use of a moving wire detector system for the study of liquid chromatographic columns. | 1967 May-Jun | Anal. Chim. Acta | pmid:6045413 |
Giacometti J | Determination of aliphatic alcohols, squalene, alpha-tocopherol and sterols in olive oils: direct method involving gas chromatography of the unsaponifiable fraction following silylation. | 2001 | Analyst | pmid:11340981 |
Morimoto Y et al. | Total synthesis and determination of the absolute configuration of (+)-omaezakianol. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19248063 |
Cornforth JW | Olefin alkylation in biosynthesis. | 1968 | Angew. Chem. Int. Ed. Engl. | pmid:4976264 |