(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| BURGESS TL and WILSON JD | Studies on hormonal regulation of squalene synthesis in preputial gland and skin of the rat. | 1963 | Proc. Soc. Exp. Biol. Med. | pmid:14016990 |
| CALTABIANO S and SPREMOLLA G | [Histological and humoral aspects of experimental atherosclerosis induced by squalene in rabbits treated with triparanol]. | 1963 | Arch Sci Med (Torino) | pmid:14017944 |
| CARAVACA J et al. | Inhibition of squalene and cholesterol biosynthesis by hepatocatalase (Caperase). | 1963 | Biochem. Biophys. Res. Commun. | pmid:14018515 |
| CORNFORTH JW et al. | Stereospecific insertion of hydrogen atom into squalene from reduced nicotinamide-adenine dinucleotides. | 1963 | Biochem. Biophys. Res. Commun. | pmid:14023096 |
| GAYLOR JL | Biosynthesis of skin sterols. III. Conversion of squalene to sterols by rat skin. | 1963 | J. Biol. Chem. | pmid:13946923 |
| GAYLOR JL | Biosynthesis of skin sterols. V. Effect of arsenite inhibition and the accumulation of labeled lanosta-7, 24-dien-3 beta-ol in rat skin. | 1963 | Arch. Biochem. Biophys. | pmid:13946925 |
| DILLER ER and HARVEY OA | INTERRELATIONSHIP OF STEROL AND FATTY ACID BIOSYNTHESIS IN RAT LIVER SLICES AS RELATED TO DIETARY LIPID. | 1964 | Biochemistry | pmid:14269326 |
| SAMUELSSON B and GOODMAN DS | STEREOCHEMISTRY AT THE CENTER OF SQUALENE DURING ITS BIOSYNTHESIS FROM FARNESYL PYROPHOSPHATE AND SUBSEQUENT CONVERSION TO CHOLESTEROL. | 1964 | J. Biol. Chem. | pmid:14114881 |
| ALEXANDER GJ and ALEXANDER RB | INHIBITION OF CHOLESTEROL SYNTHESIS IN VIVO BY A CONVULSANT, METRAZOL. | 1964 | Proc. Soc. Exp. Biol. Med. | pmid:14117448 |
| Krishna G et al. | An enzyme-bound intermediate in the conversion of farnesyl pyrophosphate to squalene. | 1964 | Biochem. Biophys. Res. Commun. | pmid:4284347 |