| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Occupational | D009783 | 12 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of (e,e,e,e)-squalene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (e,e,e,e)-squalene?
(e,e,e,e)-squalene is suspected in Hypercholesterolemia, Cataract and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,e,e,e)-squalene
PubChem Associated disorders and diseases
What pathways are associated with (e,e,e,e)-squalene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (e,e,e,e)-squalene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with (e,e,e,e)-squalene?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (e,e,e,e)-squalene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (e,e,e,e)-squalene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fox CB et al. | Immunomodulatory and physical effects of phospholipid composition in vaccine adjuvant emulsions. | 2012 | AAPS PharmSciTech | pmid:22415641 |
| Arias JL et al. | Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics. | 2011 | ACS Nano | pmid:21275408 |
| Maksimenko A et al. | Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacy. | 2014 | ACS Nano | pmid:24555414 |
| Sémiramoth N et al. | Self-assembled squalenoylated penicillin bioconjugates: an original approach for the treatment of intracellular infections. | 2012 | ACS Nano | pmid:22482704 |
| Jawaid AM et al. | Shape-controlled colloidal synthesis of rock-salt lead selenide nanocrystals. | 2011 | ACS Nano | pmid:21770427 |
| Schubert K and Schumann W | [On the biosynthesis of sterines]. | 1967 | Acta Biol. Med. Ger. | pmid:5593407 |
| Mullakhanbhai MF and Francis GW | Bacterial lipids. 1. Lipid constituents of a moderately halophilic bacterium. | 1972 | Acta Chem Scand | pmid:5049648 |
| Liu CI et al. | Structural insights into the catalytic mechanism of human squalene synthase. | 2014 | Acta Crystallogr. D Biol. Crystallogr. | pmid:24531458 |
| Cunliffe WJ et al. | An explanation fro chloracne -- an industrial hazard. | 1975 | Acta Derm. Venereol. | pmid:50695 |
| Cotterill JA et al. | Variation in skin surface lipid composition and sebum excretion rate with time. | 1973 | Acta Derm. Venereol. | pmid:4127454 |