MeSH term | MeSH ID | Detail |
---|---|---|
Adrenoleukodystrophy | D000326 | 29 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
Trans-selacholeic acid is a lipid of Fatty Acyls (FA) class. Trans-selacholeic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Metabolic syndrome. The involved functions are known as Inflammation, Insulin Resistance and Synthesis. The associated genes with Trans-selacholeic acid are TNF gene and CCL2 gene. The related lipids are nervonic acid, palmitoleic acid and Sphingolipids.
To understand associated biological information of Trans-selacholeic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Trans-selacholeic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Trans-selacholeic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Adrenoleukodystrophy | D000326 | 29 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kasai N et al. | Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. | 2005 | FEBS J. | pmid:16128805 |
Oda E et al. | Relationships between serum unsaturated fatty acids and coronary risk factors: negative relations between nervonic acid and obesity-related risk factors. | 2005 | Int Heart J | pmid:16394593 |
Chen JR et al. | Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan. | 2004 | J. Nutr. Biochem. | pmid:15302081 |
Sala-Vila A et al. | The source of long-chain PUFA in formula supplements does not affect the fatty acid composition of plasma lipids in full-term infants. | 2004 | J. Nutr. | pmid:15051839 |
Bettger WJ et al. | Nervonic acid is transferred from the maternal diet to milk and tissues of suckling rat pups. | 2003 | J. Nutr. Biochem. | pmid:12742544 |
Agazzi ME et al. | In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products. | 2003 | Anal Bioanal Chem | pmid:12732919 |
Weidner E and Findley A | Catalase in microsporidian spores before and during discharge. | 2003 | Biol. Bull. | pmid:14583549 |
Kasai N et al. | Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. | 2002 | J. Biochem. | pmid:12417034 |
Mizushina Y et al. | Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. | 2000 | J. Mol. Biol. | pmid:11090281 |
Mizushina Y et al. | Mode analysis of binding of fatty acids to mammalian DNA polymerases. | 2000 | Biochim. Biophys. Acta | pmid:10903472 |
Dadras SS et al. | Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. | 1998 | Int. J. Oncol. | pmid:9454884 |
Sandhir R et al. | Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. | 1998 | J. Lipid Res. | pmid:9799802 |
Cheng C et al. | Charge-remote fragmentations are energy-dependent processes. | 1998 | J. Am. Soc. Mass Spectrom. | pmid:9692256 |
Mizushina Y et al. | The inhibitory action of fatty acids on DNA polymerase beta. | 1997 | Biochim. Biophys. Acta | pmid:9367179 |
Sargent JR et al. | Nervonic acid and demyelinating disease. | 1994 | Med. Hypotheses | pmid:8072429 |
Saito M and Saito M | Incorporation of very-long-chain fatty acids into sphingolipids of cultured neural cells. | 1991 | J. Neurochem. | pmid:2072097 |
Kushi Y et al. | Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. | 1983 | J. Biochem. | pmid:6671968 |
Lecerf J | Evidence of accumulation of ceramides containing [14C]nervonic acid in the rat lung following injection of [14C]erucic acid. | 1980 | Biochim. Biophys. Acta | pmid:7370286 |
Patel TB and Clark JB | Comparison of the development of the fatty acid content and composition of the brain of a precocial species (guinea pig) and a non-precocial species (rat). | 1980 | J. Neurochem. | pmid:7452251 |
FULCO AJ and MEAD JF | The biosynthesis of lignoceric, cerebronic, and nervonic acids. | 1961 | J. Biol. Chem. | pmid:13702539 |