MeSH term | MeSH ID | Detail |
---|---|---|
Adrenoleukodystrophy | D000326 | 29 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
Trans-selacholeic acid is a lipid of Fatty Acyls (FA) class. Trans-selacholeic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Metabolic syndrome. The involved functions are known as Inflammation, Insulin Resistance and Synthesis. The associated genes with Trans-selacholeic acid are TNF gene and CCL2 gene. The related lipids are nervonic acid, palmitoleic acid and Sphingolipids.
To understand associated biological information of Trans-selacholeic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Trans-selacholeic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Trans-selacholeic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Adrenoleukodystrophy | D000326 | 29 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Mizushina Y et al. | Mode analysis of binding of fatty acids to mammalian DNA polymerases. | 2000 | Biochim. Biophys. Acta | pmid:10903472 |
Mizushina Y et al. | Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. | 2000 | J. Mol. Biol. | pmid:11090281 |
Kasai N et al. | Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. | 2002 | J. Biochem. | pmid:12417034 |
Agazzi ME et al. | In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products. | 2003 | Anal Bioanal Chem | pmid:12732919 |
Bettger WJ et al. | Nervonic acid is transferred from the maternal diet to milk and tissues of suckling rat pups. | 2003 | J. Nutr. Biochem. | pmid:12742544 |
FULCO AJ and MEAD JF | The biosynthesis of lignoceric, cerebronic, and nervonic acids. | 1961 | J. Biol. Chem. | pmid:13702539 |
Weidner E and Findley A | Catalase in microsporidian spores before and during discharge. | 2003 | Biol. Bull. | pmid:14583549 |
Sala-Vila A et al. | The source of long-chain PUFA in formula supplements does not affect the fatty acid composition of plasma lipids in full-term infants. | 2004 | J. Nutr. | pmid:15051839 |
Chen JR et al. | Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan. | 2004 | J. Nutr. Biochem. | pmid:15302081 |
Kasai N et al. | Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. | 2005 | FEBS J. | pmid:16128805 |
Erkkilä AT et al. | Association between school performance, breast milk intake and fatty acid profile of serum lipids in ten-year-old cleft children. | 2005 | J Craniofac Surg | pmid:16192854 |
Oda E et al. | Relationships between serum unsaturated fatty acids and coronary risk factors: negative relations between nervonic acid and obesity-related risk factors. | 2005 | Int Heart J | pmid:16394593 |
Singh B et al. | Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn. | 2006 | Phytother Res | pmid:16841368 |
Murakami S et al. | Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16996474 |
Odabasi E et al. | Lipophilic components of different therapeutic mud species. | 2007 | J Altern Complement Med | pmid:18166123 |
Guo Y et al. | Increase in nervonic acid content in transformed yeast and transgenic plants by introduction of a Lunaria annua L. 3-ketoacyl-CoA synthase (KCS) gene. | 2009 | Plant Mol. Biol. | pmid:19082744 |
Yang J et al. | Study of the inhibitory effect of fatty acids on the interaction between DNA and polymerase beta. | 2009 | Biochemistry Mosc. | pmid:19747104 |
Taylor DC et al. | Molecular cloning and characterization of a KCS gene from Cardamine graeca and its heterologous expression in Brassica oilseeds to engineer high nervonic acid oils for potential medical and industrial use. | 2009 | Plant Biotechnol. J. | pmid:19843251 |
Vluggens A et al. | Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. | 2010 | Lab. Invest. | pmid:20195242 |
Saito M and Saito M | Incorporation of very-long-chain fatty acids into sphingolipids of cultured neural cells. | 1991 | J. Neurochem. | pmid:2072097 |
Impallomeni G et al. | Synthesis and characterization of poly(3-hydroxyalkanoates) from Brassica carinata oil with high content of erucic acid and from very long chain fatty acids. | 2011 | Int. J. Biol. Macromol. | pmid:21035502 |
Shearer GC et al. | Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality. | 2012 | J Ren Nutr | pmid:21775161 |
Dhobale MV et al. | Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21816593 |
Amminger GP et al. | Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seeking ultra-high-risk individuals. | 2012 | Mol. Psychiatry | pmid:22182937 |
Snigdha S et al. | Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. | 2012 | Neuroscience | pmid:22183056 |
Peters BD et al. | Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. | 2013 | Schizophr Bull | pmid:22927668 |
Ntoumani E et al. | Nervonic acid is much lower in donor milk than in milk from mothers delivering premature infants--of neglected importance? | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23870193 |
Yamazaki Y et al. | Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome. | 2014 | J Oleo Sci | pmid:24770479 |
Umemoto H et al. | Fermentative production of nervonic acid by Mortierella capitata RD000969. | 2014 | J Oleo Sci | pmid:24919474 |
pmid:25172358 | ||||
Pickens CA et al. | Plasma phospholipids, non-esterified plasma polyunsaturated fatty acids and oxylipids are associated with BMI. | 2015 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:25559239 |
Huai D et al. | Combinatorial Effects of Fatty Acid Elongase Enzymes on Nervonic Acid Production in Camelina sativa. | 2015 | PLoS ONE | pmid:26121034 |
Medema S et al. | Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. | 2016 | Schizophr Bull | pmid:26385764 |
pmid:26858144 | ||||
pmid:27765078 | ||||
Kushi Y et al. | Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. | 1983 | J. Biochem. | pmid:6671968 |
Lecerf J | Evidence of accumulation of ceramides containing [14C]nervonic acid in the rat lung following injection of [14C]erucic acid. | 1980 | Biochim. Biophys. Acta | pmid:7370286 |
Patel TB and Clark JB | Comparison of the development of the fatty acid content and composition of the brain of a precocial species (guinea pig) and a non-precocial species (rat). | 1980 | J. Neurochem. | pmid:7452251 |
Sargent JR et al. | Nervonic acid and demyelinating disease. | 1994 | Med. Hypotheses | pmid:8072429 |
Mizushina Y et al. | The inhibitory action of fatty acids on DNA polymerase beta. | 1997 | Biochim. Biophys. Acta | pmid:9367179 |
Dadras SS et al. | Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. | 1998 | Int. J. Oncol. | pmid:9454884 |
Cheng C et al. | Charge-remote fragmentations are energy-dependent processes. | 1998 | J. Am. Soc. Mass Spectrom. | pmid:9692256 |
Sandhir R et al. | Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. | 1998 | J. Lipid Res. | pmid:9799802 |