Trans-selacholeic acid

Trans-selacholeic acid is a lipid of Fatty Acyls (FA) class. Trans-selacholeic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Metabolic syndrome. The involved functions are known as Inflammation, Insulin Resistance and Synthesis. The associated genes with Trans-selacholeic acid are TNF gene and CCL2 gene. The related lipids are nervonic acid, palmitoleic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Trans-selacholeic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Trans-selacholeic acid?

Trans-selacholeic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Trans-selacholeic acid

MeSH term MeSH ID Detail
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Trans-selacholeic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Trans-selacholeic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Trans-selacholeic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Trans-selacholeic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Trans-selacholeic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Trans-selacholeic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Trans-selacholeic acid

Download all related citations
Per page 10 20 50 | Total 44
Authors Title Published Journal PubMed Link
Medema S et al. Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. 2016 Schizophr Bull pmid:26385764
Huai D et al. Combinatorial Effects of Fatty Acid Elongase Enzymes on Nervonic Acid Production in Camelina sativa. 2015 PLoS ONE pmid:26121034
Pickens CA et al. Plasma phospholipids, non-esterified plasma polyunsaturated fatty acids and oxylipids are associated with BMI. 2015 Prostaglandins Leukot. Essent. Fatty Acids pmid:25559239
Umemoto H et al. Fermentative production of nervonic acid by Mortierella capitata RD000969. 2014 J Oleo Sci pmid:24919474
Yamazaki Y et al. Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome. 2014 J Oleo Sci pmid:24770479
Peters BD et al. Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. 2013 Schizophr Bull pmid:22927668
Ntoumani E et al. Nervonic acid is much lower in donor milk than in milk from mothers delivering premature infants--of neglected importance? 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23870193
Snigdha S et al. Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. 2012 Neuroscience pmid:22183056
Amminger GP et al. Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seeking ultra-high-risk individuals. 2012 Mol. Psychiatry pmid:22182937
Shearer GC et al. Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality. 2012 J Ren Nutr pmid:21775161
Dhobale MV et al. Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries. 2011 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:21816593
Impallomeni G et al. Synthesis and characterization of poly(3-hydroxyalkanoates) from Brassica carinata oil with high content of erucic acid and from very long chain fatty acids. 2011 Int. J. Biol. Macromol. pmid:21035502
Vluggens A et al. Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. 2010 Lab. Invest. pmid:20195242
Taylor DC et al. Molecular cloning and characterization of a KCS gene from Cardamine graeca and its heterologous expression in Brassica oilseeds to engineer high nervonic acid oils for potential medical and industrial use. 2009 Plant Biotechnol. J. pmid:19843251
Yang J et al. Study of the inhibitory effect of fatty acids on the interaction between DNA and polymerase beta. 2009 Biochemistry Mosc. pmid:19747104
Guo Y et al. Increase in nervonic acid content in transformed yeast and transgenic plants by introduction of a Lunaria annua L. 3-ketoacyl-CoA synthase (KCS) gene. 2009 Plant Mol. Biol. pmid:19082744
Odabasi E et al. Lipophilic components of different therapeutic mud species. 2007 J Altern Complement Med pmid:18166123
Murakami S et al. Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. 2006 Biochem. Biophys. Res. Commun. pmid:16996474
Singh B et al. Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn. 2006 Phytother Res pmid:16841368
Oda E et al. Relationships between serum unsaturated fatty acids and coronary risk factors: negative relations between nervonic acid and obesity-related risk factors. 2005 Int Heart J pmid:16394593
Kasai N et al. Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. 2005 FEBS J. pmid:16128805
Erkkilä AT et al. Association between school performance, breast milk intake and fatty acid profile of serum lipids in ten-year-old cleft children. 2005 J Craniofac Surg pmid:16192854
Sala-Vila A et al. The source of long-chain PUFA in formula supplements does not affect the fatty acid composition of plasma lipids in full-term infants. 2004 J. Nutr. pmid:15051839
Chen JR et al. Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan. 2004 J. Nutr. Biochem. pmid:15302081
Weidner E and Findley A Catalase in microsporidian spores before and during discharge. 2003 Biol. Bull. pmid:14583549
Bettger WJ et al. Nervonic acid is transferred from the maternal diet to milk and tissues of suckling rat pups. 2003 J. Nutr. Biochem. pmid:12742544
Agazzi ME et al. In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products. 2003 Anal Bioanal Chem pmid:12732919
Kasai N et al. Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. 2002 J. Biochem. pmid:12417034
Mizushina Y et al. Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. 2000 J. Mol. Biol. pmid:11090281
Mizushina Y et al. Mode analysis of binding of fatty acids to mammalian DNA polymerases. 2000 Biochim. Biophys. Acta pmid:10903472
Sandhir R et al. Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. 1998 J. Lipid Res. pmid:9799802
Cheng C et al. Charge-remote fragmentations are energy-dependent processes. 1998 J. Am. Soc. Mass Spectrom. pmid:9692256
Dadras SS et al. Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. 1998 Int. J. Oncol. pmid:9454884
Mizushina Y et al. The inhibitory action of fatty acids on DNA polymerase beta. 1997 Biochim. Biophys. Acta pmid:9367179
Sargent JR et al. Nervonic acid and demyelinating disease. 1994 Med. Hypotheses pmid:8072429
Saito M and Saito M Incorporation of very-long-chain fatty acids into sphingolipids of cultured neural cells. 1991 J. Neurochem. pmid:2072097
Kushi Y et al. Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. 1983 J. Biochem. pmid:6671968
Patel TB and Clark JB Comparison of the development of the fatty acid content and composition of the brain of a precocial species (guinea pig) and a non-precocial species (rat). 1980 J. Neurochem. pmid:7452251
Lecerf J Evidence of accumulation of ceramides containing [14C]nervonic acid in the rat lung following injection of [14C]erucic acid. 1980 Biochim. Biophys. Acta pmid:7370286
FULCO AJ and MEAD JF The biosynthesis of lignoceric, cerebronic, and nervonic acids. 1961 J. Biol. Chem. pmid:13702539
pmid:
pmid:27765078
pmid:26858144
pmid:25172358