Trans-selacholeic acid

Trans-selacholeic acid is a lipid of Fatty Acyls (FA) class. Trans-selacholeic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Metabolic syndrome. The involved functions are known as Inflammation, Insulin Resistance and Synthesis. The associated genes with Trans-selacholeic acid are TNF gene and CCL2 gene. The related lipids are nervonic acid, palmitoleic acid and Sphingolipids.

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Introduction

To understand associated biological information of Trans-selacholeic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Trans-selacholeic acid?

Trans-selacholeic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Trans-selacholeic acid

MeSH term MeSH ID Detail
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Trans-selacholeic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Trans-selacholeic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Trans-selacholeic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Trans-selacholeic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Trans-selacholeic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Trans-selacholeic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Trans-selacholeic acid

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Authors Title Published Journal PubMed Link
pmid:27765078
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Agazzi ME et al. In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products. 2003 Anal Bioanal Chem pmid:12732919
Murakami S et al. Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. 2006 Biochem. Biophys. Res. Commun. pmid:16996474
Yang J et al. Study of the inhibitory effect of fatty acids on the interaction between DNA and polymerase beta. 2009 Biochemistry Mosc. pmid:19747104
Lecerf J Evidence of accumulation of ceramides containing [14C]nervonic acid in the rat lung following injection of [14C]erucic acid. 1980 Biochim. Biophys. Acta pmid:7370286
Mizushina Y et al. The inhibitory action of fatty acids on DNA polymerase beta. 1997 Biochim. Biophys. Acta pmid:9367179
Mizushina Y et al. Mode analysis of binding of fatty acids to mammalian DNA polymerases. 2000 Biochim. Biophys. Acta pmid:10903472
Weidner E and Findley A Catalase in microsporidian spores before and during discharge. 2003 Biol. Bull. pmid:14583549
Kasai N et al. Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. 2005 FEBS J. pmid:16128805
Oda E et al. Relationships between serum unsaturated fatty acids and coronary risk factors: negative relations between nervonic acid and obesity-related risk factors. 2005 Int Heart J pmid:16394593
Impallomeni G et al. Synthesis and characterization of poly(3-hydroxyalkanoates) from Brassica carinata oil with high content of erucic acid and from very long chain fatty acids. 2011 Int. J. Biol. Macromol. pmid:21035502
Dadras SS et al. Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. 1998 Int. J. Oncol. pmid:9454884
Odabasi E et al. Lipophilic components of different therapeutic mud species. 2007 J Altern Complement Med pmid:18166123
Erkkilä AT et al. Association between school performance, breast milk intake and fatty acid profile of serum lipids in ten-year-old cleft children. 2005 J Craniofac Surg pmid:16192854
Umemoto H et al. Fermentative production of nervonic acid by Mortierella capitata RD000969. 2014 J Oleo Sci pmid:24919474
Yamazaki Y et al. Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome. 2014 J Oleo Sci pmid:24770479
Shearer GC et al. Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality. 2012 J Ren Nutr pmid:21775161